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01-12-2022 | Amphotericin B | Case Report

Unusual Presentation of Blastomycosis as Anterior Neck Swelling

Authors: Akshara S. Prasad, Vipin V. Nair, R. Nagamahendran, Jafar Husain

Published in: Indian Journal of Surgery | Issue 5/2023

Abstract

Blastomycosis is a chronic systemic pyogranulomatous infection caused by the fungus Blastomyces dermatitidis, endemic to North America (Mazi et al. in Infect Dis Clin North Am 35(2):515–530, 2021). This is a dimorphic fungus, which exists as a non-pathogenic mycelial form in nature and converts to pathogenic yeast at body temperature. Although it primarily affects lungs, extrapulmonary involvement is reported in 20–30% cases and is very rare (Ballestas et al. in J Voice 36(6):881.e1-881.e3, 2022). We report an unusual case of blastomycosis involving the mediastinum, presented to us as an anterior neck swelling in an immunocompetent young male.

Mazi PB, Rauseo AM, Spec A (2021) Blastomycosis. Infect Dis Clin North Am 35(2):515–530. https://doi.org/10.1016/j.idc.2021.03.013CrossRefPubMed

Ballestas SA, Magliocca KR, Balter L, Hatcher JL (2022) Laryngeal blastomycosis, an unexpected diagnosis: a case report. J Voice 36(6):881.e1–881.e3. https://doi.org/10.1016/j.jvoice.2020.09.015

Grennan D, Alvi S, Jhaveri MD, Lin MY, Wiet RM (2020) Complicated blastomycosis of the skull base presenting as otitis media. JAMA Otolaryngol Head Neck Surg 146(1):81–82. https://doi.org/10.1001/jamaoto.2019.3241CrossRefPubMed

Mutalik VS, Bissonnette C, Kalmar JR, McNamara KK (2021) Unique oral presentations of deep fungal infections: a report of four cases. Head Neck Pathol. 15(2):682–690. https://doi.org/10.1007/s12105-020-01217-0CrossRefPubMed

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Title: Unusual Presentation of Blastomycosis as Anterior Neck Swelling
Authors: Akshara S. Prasad
Vipin V. Nair
R. Nagamahendran
Jafar Husain
Publication date: 01-12-2022
Publisher: Springer India
Keywords: Amphotericin B
Itraconazole
Published in: Indian Journal of Surgery / Issue 5/2023
Print ISSN: 0972-2068
Electronic ISSN: 0973-9793
DOI: https://doi.org/10.1007/s12262-022-03617-8

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Unusual Presentation of Blastomycosis as Anterior Neck Swelling

Abstract

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Abstract

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