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Published in: Indian Journal of Surgery 4/2015

01-08-2015 | REVIEW ARTICLE

Postoperative Mesh Infection—Still a Concern in Laparoscopic Era

Authors: Rajvilas Narkhede, N. M. Shah, P. R. Dalal, Chirantan Mangukia, Shreyas Dholaria

Published in: Indian Journal of Surgery | Issue 4/2015

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Abstract

Introduction of synthetic mesh was a landmark breakthrough in the management of hernia repair and has significantly reduced recurrence rates. But in addition to the benefits, some more problems have come in picture major being ‘mesh infection’. Prolene mesh has shown promise when used in abdominal and inguinal hernia repair, especially when used in planned surgeries. This material, derived from monofilament polypropelene, is found to be biologically inert in almost every person. Being a foreign material, a slightest breach in asepsis can lead to favourable environment for bacterial proliferation and form a ‘biofilm’. This phenomenon especially after laparoscopic surgeries gives rise to chronic discharging sinus at the port site, abscess formation around mesh and even sepsis. It appears that laparoscopic hernia repair is a promising method but having chances of mesh infection owing to difficult approach and lack of uniformity in sterilization of laparoscopic instruments. Slightest breach in sterility or protocols might lead to such a large ventral wall sinus, increasing morbidity and cost of treatment. Treatment of infected mesh is possible by local debridement, irrigation, mesh removal and systemic antibiotics culminating in increased morbidity over duration of disease, but still it would be worth emphasizing—‘Prevention is better than cure’.
Literature
1.
go back to reference Paton BL et al (2007) Management of infections of polytetrafluoroethylene-based mesh. Surg Infect (Larchmt) 8(3):337–341CrossRef Paton BL et al (2007) Management of infections of polytetrafluoroethylene-based mesh. Surg Infect (Larchmt) 8(3):337–341CrossRef
2.
go back to reference Turner EJ, Owen E, Reddy K (2009) Necrotising fasciitis following inguinal hernia repair. BMJ Case Rep Turner EJ, Owen E, Reddy K (2009) Necrotising fasciitis following inguinal hernia repair. BMJ Case Rep
3.
go back to reference Sanchez VM, Abi-Haidar YE, Itani KM (2011) Mesh infection in ventral incisional hernia repair: incidence, contributing factors, and treatment. Surg Infect (Larchmt) 12(3):205–210CrossRef Sanchez VM, Abi-Haidar YE, Itani KM (2011) Mesh infection in ventral incisional hernia repair: incidence, contributing factors, and treatment. Surg Infect (Larchmt) 12(3):205–210CrossRef
4.
go back to reference Mavros MN et al (2011) Risk factors for mesh-related infections after hernia repair surgery: a meta-analysis of cohort studies. World J Surg 35(11):2389–2398PubMedCrossRef Mavros MN et al (2011) Risk factors for mesh-related infections after hernia repair surgery: a meta-analysis of cohort studies. World J Surg 35(11):2389–2398PubMedCrossRef
5.
go back to reference Harrell A et al (2006) In vitro infectability of prosthetic mesh by methicillin-resistant Staphylococcus aureus. Hernia 10(2):120–124PubMedCrossRef Harrell A et al (2006) In vitro infectability of prosthetic mesh by methicillin-resistant Staphylococcus aureus. Hernia 10(2):120–124PubMedCrossRef
6.
go back to reference Halaweish I et al (2010) Novel in vitro model for assessing susceptibility of synthetic hernia repair meshes to staphylococcus aureus infection using green fluorescent protein-labeled bacteria and modern imaging techniques. Surg Infect (Larchmt) 11(5):449–454CrossRef Halaweish I et al (2010) Novel in vitro model for assessing susceptibility of synthetic hernia repair meshes to staphylococcus aureus infection using green fluorescent protein-labeled bacteria and modern imaging techniques. Surg Infect (Larchmt) 11(5):449–454CrossRef
7.
go back to reference Vivian M Sanchez, Abi.-Haidar YE, Kamal MF Itani Mesh infection in ventral incisional hernia repair: incidence, contributing factors, and treatment Vivian M Sanchez, Abi.-Haidar YE, Kamal MF Itani Mesh infection in ventral incisional hernia repair: incidence, contributing factors, and treatment
8.
go back to reference Leber GE et al (1998) Long-term complications associated with prosthetic repair of incisional hernias. Arch Surg 133(4):378–382PubMedCrossRef Leber GE et al (1998) Long-term complications associated with prosthetic repair of incisional hernias. Arch Surg 133(4):378–382PubMedCrossRef
9.
go back to reference Engelsman AF et al (2010) In vivo evaluation of bacterial infection involving morphologically different surgical meshes. Ann Surg 251(1):133–137PubMedCrossRef Engelsman AF et al (2010) In vivo evaluation of bacterial infection involving morphologically different surgical meshes. Ann Surg 251(1):133–137PubMedCrossRef
10.
go back to reference Robinson T et al (2005) Major mesh-related complications following hernia repair. Surg Endosc 19(12):1556–1560PubMedCrossRef Robinson T et al (2005) Major mesh-related complications following hernia repair. Surg Endosc 19(12):1556–1560PubMedCrossRef
11.
go back to reference Engelsman AF et al (2007) The phenomenon of infection with abdominal wall reconstruction. Biomaterials 28(14):2314–2327PubMedCrossRef Engelsman AF et al (2007) The phenomenon of infection with abdominal wall reconstruction. Biomaterials 28(14):2314–2327PubMedCrossRef
12.
go back to reference Wallace RJ Jr et al (1988) Human disease due to mycobacterium smegmatis. J Infect Dis 158(1):52–59PubMedCrossRef Wallace RJ Jr et al (1988) Human disease due to mycobacterium smegmatis. J Infect Dis 158(1):52–59PubMedCrossRef
13.
go back to reference LeBlanc KA et al (2003) Laparoscopic incisional and ventral hernioplasty: lessons learned from 200 patients. Hernia 7(3):118–124PubMedCrossRef LeBlanc KA et al (2003) Laparoscopic incisional and ventral hernioplasty: lessons learned from 200 patients. Hernia 7(3):118–124PubMedCrossRef
14.
go back to reference Rios A et al (2001) Antibiotic prophylaxis in incisional hernia repair using a prosthesis. Hernia 5(3):148–152PubMedCrossRef Rios A et al (2001) Antibiotic prophylaxis in incisional hernia repair using a prosthesis. Hernia 5(3):148–152PubMedCrossRef
15.
go back to reference Klinge U et al (2002) Do multifilament alloplastic meshes increase the infection rate? Analysis of the polymeric surface, the bacteria adherence, and the in vivo consequences in a rat model. J Biomed Mater Res 63(6):765–771PubMedCrossRef Klinge U et al (2002) Do multifilament alloplastic meshes increase the infection rate? Analysis of the polymeric surface, the bacteria adherence, and the in vivo consequences in a rat model. J Biomed Mater Res 63(6):765–771PubMedCrossRef
16.
go back to reference Taylor SG, O'Dwyer PJ (1999) Chronic groin sepsis following tension-free inguinal hernioplasty. Br J Surg 86(4):562–565PubMedCrossRef Taylor SG, O'Dwyer PJ (1999) Chronic groin sepsis following tension-free inguinal hernioplasty. Br J Surg 86(4):562–565PubMedCrossRef
17.
go back to reference An YH, Friedman RJ (1998) Concise review of mechanisms of bacterial adhesion to biomaterial surfaces. J Biomed Mater Res 43(3):338–348PubMedCrossRef An YH, Friedman RJ (1998) Concise review of mechanisms of bacterial adhesion to biomaterial surfaces. J Biomed Mater Res 43(3):338–348PubMedCrossRef
18.
go back to reference Falagas ME, Kasiakou SK (2005) Mesh-related infections after hernia repair surgery. Clin Microbiol Infect 11(1):3–8PubMedCrossRef Falagas ME, Kasiakou SK (2005) Mesh-related infections after hernia repair surgery. Clin Microbiol Infect 11(1):3–8PubMedCrossRef
19.
go back to reference Jass J, Surman S, Walker JT (2005) Microbial biofilms in medicine, in medical biofilms. Wiley 1–28 Jass J, Surman S, Walker JT (2005) Microbial biofilms in medicine, in medical biofilms. Wiley 1–28
21.
go back to reference Deepraj S, Bhandarkar ANK Sterilization and maintenance of instruments & equipment Deepraj S, Bhandarkar ANK Sterilization and maintenance of instruments & equipment
22.
go back to reference Griffith DE, Wallace RJ Jr. (2003) Microbiology of nontuberculous mycobacteria Griffith DE, Wallace RJ Jr. (2003) Microbiology of nontuberculous mycobacteria
24.
25.
go back to reference Broll R et al (2002) Influence of resterilized polypropylen meshes on growth of human fibroblasts—an experimental in vitro study. Zentralbl Chir 127(7):589–593PubMedCrossRef Broll R et al (2002) Influence of resterilized polypropylen meshes on growth of human fibroblasts—an experimental in vitro study. Zentralbl Chir 127(7):589–593PubMedCrossRef
26.
go back to reference Corson SL et al (1979) Sterilization of laparoscopes. Is soaking sufficient? J Reprod Med 23(2):49–56PubMed Corson SL et al (1979) Sterilization of laparoscopes. Is soaking sufficient? J Reprod Med 23(2):49–56PubMed
27.
go back to reference Matthias Friedrich SM, Wedel T, Fischer F, Roblick UJ, Habermann J, Bruch H-P, Farke S (2010) Effects of resterilization on the surface-structure of lightweight polypropylene hernia meshes—an in vitro study. Res J Med Sci 4(5):330–333 Matthias Friedrich SM, Wedel T, Fischer F, Roblick UJ, Habermann J, Bruch H-P, Farke S (2010) Effects of resterilization on the surface-structure of lightweight polypropylene hernia meshes—an in vitro study. Res J Med Sci 4(5):330–333
28.
go back to reference Serbetci K et al (2007) Effects of resterilization on mechanical properties of polypropylene meshes. Am J Surg 194(3):375–379PubMedCrossRef Serbetci K et al (2007) Effects of resterilization on mechanical properties of polypropylene meshes. Am J Surg 194(3):375–379PubMedCrossRef
29.
go back to reference Heath Dorion M, Brian Gruber MD Pathogenesis of surgical site infection (SSI) Heath Dorion M, Brian Gruber MD Pathogenesis of surgical site infection (SSI)
30.
go back to reference Avtan L et al (1997) Mesh infections after laparoscopic inguinal hernia repair. Surg Laparosc Endosc Percutaneous Tech 7(3):192–195CrossRef Avtan L et al (1997) Mesh infections after laparoscopic inguinal hernia repair. Surg Laparosc Endosc Percutaneous Tech 7(3):192–195CrossRef
31.
go back to reference Marinko Žuvela AA, Djordje Bajec, Dejan Radenković, Milorad Petrović, Danijel Galun, Ivan Palibrk, Aleksandra Đurić, Zoran Raznatovic, Bojan Banko, Jovica Milovanović, Aleksandar Milovanović, Đorđije Šaranović, Vera Artiko, Dragana Šobić and Vladimir Obradović Diagnosis of mesh infection after abdominal wall hernia surgery—role of radionuclide methods Marinko Žuvela AA, Djordje Bajec, Dejan Radenković, Milorad Petrović, Danijel Galun, Ivan Palibrk, Aleksandra Đurić, Zoran Raznatovic, Bojan Banko, Jovica Milovanović, Aleksandar Milovanović, Đorđije Šaranović, Vera Artiko, Dragana Šobić and Vladimir Obradović Diagnosis of mesh infection after abdominal wall hernia surgery—role of radionuclide methods
32.
go back to reference Swenson BR et al (2008) Antimicrobial-impregnated surgical incise drapes in the prevention of mesh infection after ventral hernia repair. Surg Infect (Larchmt) 9(1):23–32CrossRef Swenson BR et al (2008) Antimicrobial-impregnated surgical incise drapes in the prevention of mesh infection after ventral hernia repair. Surg Infect (Larchmt) 9(1):23–32CrossRef
33.
go back to reference Yerdel MA et al (2001) Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial. Ann Surg 233(1):26–33PubMedPubMedCentralCrossRef Yerdel MA et al (2001) Effect of single-dose prophylactic ampicillin and sulbactam on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial. Ann Surg 233(1):26–33PubMedPubMedCentralCrossRef
34.
go back to reference Musella M, Guido A, Musella S (2001) Collagen tampons as aminoglycoside carriers to reduce postoperative infection rate in prosthetic repair of groin hernias. Eur J Surg 167(2):130–132PubMedCrossRef Musella M, Guido A, Musella S (2001) Collagen tampons as aminoglycoside carriers to reduce postoperative infection rate in prosthetic repair of groin hernias. Eur J Surg 167(2):130–132PubMedCrossRef
35.
go back to reference Carbonell AM et al (2005) The susceptibility of prosthetic biomaterials to infection. Surg Endosc 19(3):430–435PubMedCrossRef Carbonell AM et al (2005) The susceptibility of prosthetic biomaterials to infection. Surg Endosc 19(3):430–435PubMedCrossRef
36.
go back to reference LeBlanc Karl A, Heniford B Todd, Voeller Guy R Innovations in ventral hernia repair materials and techniques to reduce MRSA and other infections LeBlanc Karl A, Heniford B Todd, Voeller Guy R Innovations in ventral hernia repair materials and techniques to reduce MRSA and other infections
37.
go back to reference Falagas1 ME, Kasiakou ASK and Alfa A Mesh-related infections after hernia repair surgery. HealthCare, Greece and 2Tufts University School of Medicine, Boston Falagas1 ME, Kasiakou ASK and Alfa A Mesh-related infections after hernia repair surgery. HealthCare, Greece and 2Tufts University School of Medicine, Boston
38.
go back to reference Ahmad S et al (2007) Conservative management of mesh site infection in ventral hernia repair. J Ayub Med Coll Abbottabad 19(4):75–77PubMed Ahmad S et al (2007) Conservative management of mesh site infection in ventral hernia repair. J Ayub Med Coll Abbottabad 19(4):75–77PubMed
39.
go back to reference Aguilar B et al (2010) Conservative management of mesh-site infection in hernia repair. J Laparoendosc Adv Surg Tech A 20(3):249–252PubMedCrossRef Aguilar B et al (2010) Conservative management of mesh-site infection in hernia repair. J Laparoendosc Adv Surg Tech A 20(3):249–252PubMedCrossRef
40.
go back to reference Baharestani MM, Gabriel A (2011) Use of negative pressure wound therapy in the management of infected abdominal wounds containing mesh: an analysis of outcomes. Int Wound J 8(2):118–125PubMedCrossRef Baharestani MM, Gabriel A (2011) Use of negative pressure wound therapy in the management of infected abdominal wounds containing mesh: an analysis of outcomes. Int Wound J 8(2):118–125PubMedCrossRef
41.
go back to reference Tamhankar AP, Ravi K, Everitt NJ (2009) Vacuum assisted closure® therapy in the treatment of mesh infection after hernia repair. Surg J R C Surg Edinburgh Ireland 7(5):316–318 Tamhankar AP, Ravi K, Everitt NJ (2009) Vacuum assisted closure® therapy in the treatment of mesh infection after hernia repair. Surg J R C Surg Edinburgh Ireland 7(5):316–318
Metadata
Title
Postoperative Mesh Infection—Still a Concern in Laparoscopic Era
Authors
Rajvilas Narkhede
N. M. Shah
P. R. Dalal
Chirantan Mangukia
Shreyas Dholaria
Publication date
01-08-2015
Publisher
Springer India
Published in
Indian Journal of Surgery / Issue 4/2015
Print ISSN: 0972-2068
Electronic ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-015-1304-x

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