Skip to main content
Top
Published in: Indian Journal of Surgery 3/2013

01-06-2013 | Review Article

Skeletal Muscle Metastases from Pancreatic Carcinoma–A Case Report and Review of Literature

Authors: M. Meer Chisthi, P. A. Manju

Published in: Indian Journal of Surgery | Issue 3/2013

Login to get access

Abstract

With an overall mortality approaching nearly 100 %, pancreatic cancer is still a challenging disease. A major proportion of pancreatic cancers are still diagnosed at the locally advanced or metastatic stage. Tumors originating from tail region present very late due to the absence of specific symptoms and signs. The usual sites of metastases are the liver, peritoneum and lungs, with occasional reports of metastases in other sites. There are very few documented cases of gastrointestinal cancers manifesting as metastases to muscle. This is a report on a case of pancreatic cancer presenting as metastases to skeletal muscle and multiple other viscera and review of literature for pancreatic cancer metastases.
Literature
1.
go back to reference Lowenfels AB, Maisonneuve P (2008) Epidemiology of pancreatic cancer. In: Hans G Beger, Seiki Matsuno, John L Cameron, editors. Diseases of the pancreas current surgical therapy. Springer, p 489 Lowenfels AB, Maisonneuve P (2008) Epidemiology of pancreatic cancer. In: Hans G Beger, Seiki Matsuno, John L Cameron, editors. Diseases of the pancreas current surgical therapy. Springer, p 489
2.
go back to reference Abdel Hafez HZ (2007) Cutaneous pancreatic metastasis: A case report and review of literature. Indian J Cancer 44:111–114CrossRef Abdel Hafez HZ (2007) Cutaneous pancreatic metastasis: A case report and review of literature. Indian J Cancer 44:111–114CrossRef
3.
go back to reference Gouma DJ, Vervenne WL, Bush ORC (2007) Pancreatic cancer and ampullary cancer. In: Poston GJ, Beauchamp DR, Ruers TJM, (eds). Textbook of surgical oncology. Informa, p 189 Gouma DJ, Vervenne WL, Bush ORC (2007) Pancreatic cancer and ampullary cancer. In: Poston GJ, Beauchamp DR, Ruers TJM, (eds). Textbook of surgical oncology. Informa, p 189
4.
go back to reference Ahlgren JD (1996) Epidemiology and risk factors in pancreatic cancer. Semin Oncol 23:241–250PubMed Ahlgren JD (1996) Epidemiology and risk factors in pancreatic cancer. Semin Oncol 23:241–250PubMed
6.
go back to reference Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME et al (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410:50–56PubMedCrossRef Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME et al (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410:50–56PubMedCrossRef
7.
go back to reference Tawil NJ, Gowri V, Djoneidi M, Nip J, Carbonetto S, Brodt P (1996) Integrin alpha3beta1 can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma. Int J Cancer 66:703–710PubMedCrossRef Tawil NJ, Gowri V, Djoneidi M, Nip J, Carbonetto S, Brodt P (1996) Integrin alpha3beta1 can promote adhesion and spreading of metastatic breast carcinoma cells on the lymph node stroma. Int J Cancer 66:703–710PubMedCrossRef
8.
go back to reference Keleg S, Büchler P, Ludwig R, Büchler MV, Friess H (2002) Invasion and metastasis in pancreatic cancer. Mol Cancer 2:14CrossRef Keleg S, Büchler P, Ludwig R, Büchler MV, Friess H (2002) Invasion and metastasis in pancreatic cancer. Mol Cancer 2:14CrossRef
9.
go back to reference McGee SR (2001) Palpation and percussion of the abdomen. Evidence-based physical diagnosis. Philadelphia: Saunders, p 601–604 McGee SR (2001) Palpation and percussion of the abdomen. Evidence-based physical diagnosis. Philadelphia: Saunders, p 601–604
10.
go back to reference Miyahara M, Hamanaka Y, Kawabata A et al (1996) Cutaneous metastasis from pancreatic cancer. Int J Pancreatol 20:127–130PubMed Miyahara M, Hamanaka Y, Kawabata A et al (1996) Cutaneous metastasis from pancreatic cancer. Int J Pancreatol 20:127–130PubMed
11.
go back to reference Yendluri V, Centeno B, Springett GM (2007) Pancreatic cancer presenting as a Sister Mary Joseph's nodule: case report and update of the literature. Pancreas 34(1):161–164PubMedCrossRef Yendluri V, Centeno B, Springett GM (2007) Pancreatic cancer presenting as a Sister Mary Joseph's nodule: case report and update of the literature. Pancreas 34(1):161–164PubMedCrossRef
12.
go back to reference Herring CL Jr, Harrelson JM, Scully SP (1998) Metastatic carcinoma to skeletal muscle: a report of 15 patients. Clin Orthop Relat Res 355:272–281PubMedCrossRef Herring CL Jr, Harrelson JM, Scully SP (1998) Metastatic carcinoma to skeletal muscle: a report of 15 patients. Clin Orthop Relat Res 355:272–281PubMedCrossRef
13.
go back to reference Tuoheti Y, Okada K, Osanai T, Nishida J, Ehara S, Hashimoto M, Itoi E (2004) Skeletal muscle metastases of carcinoma: a clinicopathological study of 12 cases. Jpn J Clin Oncol 34(4):210–214PubMedCrossRef Tuoheti Y, Okada K, Osanai T, Nishida J, Ehara S, Hashimoto M, Itoi E (2004) Skeletal muscle metastases of carcinoma: a clinicopathological study of 12 cases. Jpn J Clin Oncol 34(4):210–214PubMedCrossRef
14.
go back to reference Larson DA, Bottles K, Federle M, Fippin L, Luce J (1988) Skeletal muscle metastases from pancreatic cancer. Onkologie 11:282–285PubMedCrossRef Larson DA, Bottles K, Federle M, Fippin L, Luce J (1988) Skeletal muscle metastases from pancreatic cancer. Onkologie 11:282–285PubMedCrossRef
15.
go back to reference Malesci A, Montorsi M, Mariani A, Santambrogio R, Bonato C, Bissi O et al (1992) Clinical utility of the serum CA 19–9 test for diagnosing pancreatic carcinoma in symptomatic patients: a prospective study. Pancreas 7:497–502PubMedCrossRef Malesci A, Montorsi M, Mariani A, Santambrogio R, Bonato C, Bissi O et al (1992) Clinical utility of the serum CA 19–9 test for diagnosing pancreatic carcinoma in symptomatic patients: a prospective study. Pancreas 7:497–502PubMedCrossRef
16.
17.
go back to reference Wiersema MJ (2001) Accuracy of endoscopic ultrasound in diagnosing and staging pancreatic carcinoma. Pancreatology 1:625–635PubMedCrossRef Wiersema MJ (2001) Accuracy of endoscopic ultrasound in diagnosing and staging pancreatic carcinoma. Pancreatology 1:625–635PubMedCrossRef
18.
go back to reference Chang KJ, Nguyen P, Erickson RA, Durbin TE, Katz KD (1997) The clinical utility of endoscopic ultrasoundguided fine-needle aspiration in the diagnosis and staging of pancreatic carcinoma. Gastrointest Endosc 45:387–393PubMedCrossRef Chang KJ, Nguyen P, Erickson RA, Durbin TE, Katz KD (1997) The clinical utility of endoscopic ultrasoundguided fine-needle aspiration in the diagnosis and staging of pancreatic carcinoma. Gastrointest Endosc 45:387–393PubMedCrossRef
19.
go back to reference Sewnath ME, Karsten TM, Prins MH, Rauws EJ, Obertop H, Gouma DJ (2002) A meta-analysis on the efficacy of pre-operative biliary drainage for tumors causing obstructive jaundice. Ann Surg 236:17–27PubMedCentralPubMedCrossRef Sewnath ME, Karsten TM, Prins MH, Rauws EJ, Obertop H, Gouma DJ (2002) A meta-analysis on the efficacy of pre-operative biliary drainage for tumors causing obstructive jaundice. Ann Surg 236:17–27PubMedCentralPubMedCrossRef
20.
go back to reference Barreiro CJ, Lillemoe KD, Koniaris LG et al (2002) Diagnostic laparoscopy for periampullary and pancreatic cancer: what is the true benefit? J Gastrointest Surg 6:75–81PubMedCrossRef Barreiro CJ, Lillemoe KD, Koniaris LG et al (2002) Diagnostic laparoscopy for periampullary and pancreatic cancer: what is the true benefit? J Gastrointest Surg 6:75–81PubMedCrossRef
22.
go back to reference Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226:248–257PubMedCentralPubMedCrossRef Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA et al (1997) Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 226:248–257PubMedCentralPubMedCrossRef
23.
go back to reference Yamada H, Hirano S, Tanaka E, Shichinohe T, Kondo S (2006) Surgical treatment of liver metastases from pancreatic cancer. HPB (Oxford) 8(2):85–88CrossRef Yamada H, Hirano S, Tanaka E, Shichinohe T, Kondo S (2006) Surgical treatment of liver metastases from pancreatic cancer. HPB (Oxford) 8(2):85–88CrossRef
24.
go back to reference Neoptolemos JP, Stocken DD, Friess H, Bassi C, Dunn JA et al (2004) A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 350:1200–1210PubMedCrossRef Neoptolemos JP, Stocken DD, Friess H, Bassi C, Dunn JA et al (2004) A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med 350:1200–1210PubMedCrossRef
Metadata
Title
Skeletal Muscle Metastases from Pancreatic Carcinoma–A Case Report and Review of Literature
Authors
M. Meer Chisthi
P. A. Manju
Publication date
01-06-2013
Publisher
Springer India
Published in
Indian Journal of Surgery / Issue 3/2013
Print ISSN: 0972-2068
Electronic ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-012-0650-1

Other articles of this Issue 3/2013

Indian Journal of Surgery 3/2013 Go to the issue