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01-05-2017 | Progress in Hematology

Guest editorial: Connecting multiple aspects of hematologic malignancies toward creation of new therapeutics

Author: Fumihiko Ishikawa

Published in: International Journal of Hematology | Issue 5/2017

Excerpt

The field of malignant stem cell research was pioneered by acute myeloid leukemia (AML) research. Every hematologist must recall an original article in Nature, 1994, in which Dr. Dick and his colleagues found preferential engraftment in immune-compromised mice by CD34⁺CD38⁻ AML cells [1]. This exciting report on phenotypic and functional heterogeneity within human AML led the way to investigations into potential heterogeneity in solid tumors as well as diverse hematologic malignancies. …

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Title: Guest editorial: Connecting multiple aspects of hematologic malignancies toward creation of new therapeutics
Author: Fumihiko Ishikawa
Publication date: 01-05-2017
Publisher: Springer Japan
Published in: International Journal of Hematology / Issue 5/2017
Print ISSN: 0925-5710
Electronic ISSN: 1865-3774
DOI: https://doi.org/10.1007/s12185-017-2200-x

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