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Current Reviews in Musculoskeletal Medicine

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01-12-2018 | Protein-Rich Plasma: From Bench to Treatment of Arthritis (S Choate and J Tokish, section editors)

Platelet-Rich Plasma and the Knee—Applications in Orthopedic Surgery

Authors: Alexander Wasserman, Graeme Matthewson, Peter MacDonald

Published in: Current Reviews in Musculoskeletal Medicine | Issue 4/2018

Abstract

Purpose of Review

To consolidate and synthesize the most recent evidence on the effects of platelet-rich plasma (PRP) in the knee with respect to osteoarthritis, meniscal injuries, ACL reconstruction, total knee arthroplasty (TKA), and high tibial osteotomy.

Recent Findings

PRP has been shown to be more beneficial in the context of knee osteoarthritis compared to both placebo and hyaluronic acid. Direct comparison with corticosteroid injections has been sparsely studied. It has also been shown to improve the clinical postoperative course in meniscal injuries and to a lesser extent TKA. Radiographic improvements without clinically significant benefits have been observed with ACL reconstructions treated with PRP.

Summary

PRP injections may be more beneficial than other current non-surgical management options for specific knee pathologies. Further research should broaden the knowledge of PRP effects on the knee, and identify the type of PRP, growth factor distribution, and route of administration associated with the most benefit.

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34.

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Title: Platelet-Rich Plasma and the Knee—Applications in Orthopedic Surgery
Authors: Alexander Wasserman
Graeme Matthewson
Peter MacDonald
Publication date: 01-12-2018
Publisher: Springer US
Published in: Current Reviews in Musculoskeletal Medicine / Issue 4/2018
Electronic ISSN: 1935-9748
DOI: https://doi.org/10.1007/s12178-018-9521-0

At a glance: The ONWARDS insulin icodec trials

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Platelet-Rich Plasma and the Knee—Applications in Orthopedic Surgery

Abstract

Purpose of Review

Recent Findings

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Abstract

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