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Annals of Behavioral Medicine
Published in: Annals of Behavioral Medicine 3/2015

01-06-2015 | Original Article

Composite Cardiovascular Risk Scores and Neuropsychological Functioning: A Meta-Analytic Review

Authors: Jonathan DeRight, Ph.D., Randall S. Jorgensen, Ph.D., Misaell J. Cabral, B.S.

Published in: Annals of Behavioral Medicine | Issue 3/2015

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Abstract

Background

The ability for patients to understand their risk for disease is important to early intervention and effective treatment. The link between individual cardiovascular risk factors and cognition has been well-established.

Purpose

This study investigated the relationship between cognition and a combination of these factors through a single composite risk score.

Methods

This study quantitatively summarized the strength of the association between composite cardiovascular risk scores and cognitive test performance using meta-analytic methods.

Results

One hundred and nine effect sizes were obtained from 19 studies employing 54,564 participants. Composite risk scores showed a significant association (r = −0.16) with cognitive test performance. Cognitive domain and age did not significantly modify this relationship.

Conclusions

Composite cardiovascular risk scores can be useful indicators of future cognition. The development of a dementia risk score using similar risk factors could aid in the assessment and lifestyle interventions of persons at risk for dementia.
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Metadata
Title
Composite Cardiovascular Risk Scores and Neuropsychological Functioning: A Meta-Analytic Review
Authors
Jonathan DeRight, Ph.D.
Randall S. Jorgensen, Ph.D.
Misaell J. Cabral, B.S.
Publication date
01-06-2015
Publisher
Springer US
Published in
Annals of Behavioral Medicine / Issue 3/2015
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-014-9681-0

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