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Published in: Annals of Behavioral Medicine 3/2012

01-06-2012 | BRIEF REPORT

History of Major Depressive Disorder Prospectively Predicts Worse Quality of Life in Women with Breast Cancer

Authors: Heather S. L. Jim, Ph.D., Brent J. Small, Ph.D., Susan Minton, D.O., Michael Andrykowski, Ph.D., Paul B. Jacobsen, Ph.D.

Published in: Annals of Behavioral Medicine | Issue 3/2012

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Abstract

Background

Data are scarce about whether past history of major depressive disorder in the absence of current depression places breast cancer patients at risk for worse quality of life.

Purpose

The current study prospectively examined quality of life during chemotherapy in breast cancer patients with a history of resolved major depressive disorder (n = 29) and no history of depression (n = 144).

Methods

Women with Stages 0–II breast cancer were assessed prior to and at the completion of chemotherapy. Major depressive disorder was assessed via structured interview and quality of life with the SF-36.

Results

Patients with past major depressive disorder displayed greater declines in physical functioning relative to patients with no history of depression (p ≤ 0.01).

Conclusions

Findings suggest that breast cancer patients with a history of resolved major depressive disorder are at increased risk for declines in physical functioning during chemotherapy relative to patients with no history of depression.
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Metadata
Title
History of Major Depressive Disorder Prospectively Predicts Worse Quality of Life in Women with Breast Cancer
Authors
Heather S. L. Jim, Ph.D.
Brent J. Small, Ph.D.
Susan Minton, D.O.
Michael Andrykowski, Ph.D.
Paul B. Jacobsen, Ph.D.
Publication date
01-06-2012
Publisher
Springer-Verlag
Published in
Annals of Behavioral Medicine / Issue 3/2012
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-011-9333-6

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