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Published in: Annals of Behavioral Medicine 3/2010

01-12-2010 | Original Article

Association of Depression with Antihypertensive Medication Adherence in Older Adults: Cross-Sectional and Longitudinal Findings from CoSMO

Authors: Marie Krousel-Wood, M.D., M.S.P.H., Tareq Islam, M.P.H., Paul Muntner, Ph.D., Elizabeth Holt, Ph.D., M.P.H., Cara Joyce, M.S., Donald E. Morisky, Sc.D., M.S.P.H., Larry S. Webber, Ph.D., Edward D. Frohlich, M.D.

Published in: Annals of Behavioral Medicine | Issue 3/2010

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Abstract

Background

Little is known about the associations between depressive symptoms, social support and antihypertensive medication adherence in older adults.

Purpose

We evaluated the cross-sectional and longitudinal associations between depressive symptoms, social support and antihypertensive medication adherence in a large cohort of older adults.

Methods

A cohort of 2,180 older adults with hypertension was administered questionnaires, which included the Center for Epidemiologic Studies-Depression Scale, the Medical Outcomes Study Social Support Index, and the hypertension-specific Morisky Medication Adherence Scale at baseline and 1 year later.

Results

Overall, 14.1% of participants had low medication adherence, 13.0% had depressive symptoms, and 33.9% had low social support. After multivariable adjustment, the odds ratios that participants with depressive symptoms and low social support would have low medication adherence were 1.96 (95% confidence interval (CI) 1.43, 2.70) and 1.27 (95% CI 0.98, 1.65), respectively, at baseline and 1.87 (95% CI 1.32, 2.66) and 1.30 (95% CI 0.98, 1.72), respectively, at 1 year follow-up.

Conclusion

Depressive symptoms may be an important modifiable barrier to antihypertensive medication adherence in older adults
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Metadata
Title
Association of Depression with Antihypertensive Medication Adherence in Older Adults: Cross-Sectional and Longitudinal Findings from CoSMO
Authors
Marie Krousel-Wood, M.D., M.S.P.H.
Tareq Islam, M.P.H.
Paul Muntner, Ph.D.
Elizabeth Holt, Ph.D., M.P.H.
Cara Joyce, M.S.
Donald E. Morisky, Sc.D., M.S.P.H.
Larry S. Webber, Ph.D.
Edward D. Frohlich, M.D.
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
Annals of Behavioral Medicine / Issue 3/2010
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-010-9217-1

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