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Annals of Behavioral Medicine
Published in: Annals of Behavioral Medicine 1/2009

01-02-2009 | Original Article

Translating Physical Activity Interventions for Breast Cancer Survivors into Practice: An Evaluation of Randomized Controlled Trials

Authors: Siobhan M. White, B.S., Edward McAuley, Ph.D., Paul A. Estabrooks, Ph.D., Kerry S. Courneya, Ph.D.

Published in: Annals of Behavioral Medicine | Issue 1/2009

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Abstract

Background

Although physical activity (PA) interventions have been effective for improving health outcomes in breast cancer survivors, little is known relative to their potential for translation into practice.

Purpose

This review was designed to provide a quantitative estimate of the reporting of both internal and external validity in recent studies of PA in breast cancer survivors (BCS).

Methods

The Reach, Efficacy/Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework was utilized to assess the reporting of internal and external validity in 25 randomized controlled trials (RCTs) of PA and BCS published between 1998 and 2008. Each trial was evaluated relative to the degree it met criteria for each of the above dimensions.

Results

The majority of studies in this review reported dimensions reflecting internal validity. The overall level of detail relative to external validity of PA interventions was rarely reported, limiting the generalizability of study findings.

Conclusions

As with many RCTs of health behavior change, detail relative to contextual elements of published PA interventions in BCS is limited. It is recommended that future physical activity interventions in BCS be designed to facilitate scalable and sustainable interventions for improving health outcomes in this population.
Literature
1.
Ries LAG, Melbert D, Krapcho M, et al., eds. SEER Cancer Statistics Review, 1975–2004. Bethesda, MD: National Cancer Institute; 2006.
2.
Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005; 55: 74–108.PubMedCrossRef
3.
Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR. Quality of life in long term, disease-free survivors of breast cancer: A follow-up study. J Natl Cancer Inst. 2002; 94: 39–49.PubMed
4.
Hewitt M, Rowland JH, Yancik R. Cancer survivors in the United States: Age, health, and disability. J Gerontol A Biol Sci Med Sci. 2003; 58: 82–91.PubMed
5.
Holmes MD, Chen WY, Feskanich D, Kroenke CH, Colditz GA. Physical activity and survival after breast cancer diagnosis. JAMA. 2005; 293: 2479–2486.PubMedCrossRef
6.
Kirshbaum MN. A review of the benefits of whole body exercise during and after treatment for breast cancer. J Clin Nurs. 2007; 16: 104–121.PubMedCrossRef
7.
McNeely ML, Campbell KL, Rowe BH, Klassen TP, Mackey JR, Courneya KS. Effects of exercise on breast cancer patients and survivors: A systematic review and meta-analysis. Can Med Assoc J. 2006; 175: 34–41.CrossRef
8.
Redd WH, Montgomery GH, DuHamel KN. Behavioral intervention for cancer treatment side effects. J Natl Cancer Inst. 2001; 93: 810–823.PubMedCrossRef
9.
Holick CN, Newcomb PA, Trentham-Dietz A, et al. Physical activity and survival after diagnosis of invasive breast cancer. Cancer Epidemiol Biomarkers Prev. 2008; 17: 379–386.PubMedCrossRef
10.
Glasgow RE, Klesges LM, Dzewaltowski DA, Bull SS, Estabrooks P. The future of behavior change research: What is needed to improve translation of research into health promotion practice. Ann Behav Med. 2004; 27: 3–12.PubMedCrossRef
11.
Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: The RE-AIM framework. Am J Public Health. 1999; 89: 1322–1327.PubMedCrossRef
12.
Estabrooks PA, Gyurcsik NC. Evaluating the impact of behavioral interventions that target physical activity: Issues of generalizability and public health. Psychol Sport Exerc. 2003; 4: 41–55.CrossRef
13.
Glasgow RE. Chapter 23: Evaluation of theory-based interventions: The RE-AIM model. In: Glanz K, Rimer BK, Lewis FM, eds. Health Behavior and Health Education. San Francisco: Wiley; 2002.
14.
Glasgow RE, Nelson CC, Strycker LA, King DK. Using RE-AIM metrics to evaluate diabetes self-management support interventions. Am J Prev Med. 2006; 30: 67–73.PubMedCrossRef
15.
Glasgow RE, McKay HG, Piette JD, Reynolds KD. The RE-AIM framework for evaluating interventions: What can it tell us about approaches to chronic illness management. Patient Educ Couns. 2001; 44: 119–127.PubMedCrossRef
16.
Glasgow RE, Klesges LM, Dzewaltowski DA, Estabrooks PA, Vogt TM. Evaluating the impact of health promotion programs: Using the RE-AIM framework to form summary measures for decision making involving complex issues. Health Educ Res. 2006; 21: 688–694.PubMedCrossRef
17.
Courneya KS, Segal RJ, Mackey JR, et al. Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A multicenter randomized controlled trial. J Clin Oncol. 2007; 25: 4396–4404.PubMedCrossRef
18.
Daley AJ, Crank H, Saxton JM, Mutrie N, Coleman R, Roalfe A. Randomized trial of exercise therapy in women treated for breast cancer. J Clin Oncol. 2007; 25: 1713–1721.PubMedCrossRef
19.
Ware J, Sherbourne C. The MOS 36-item short-form health survey (SF-36): I. Conceptual framework and item selection. Med Care. 1992; 30: 473–483.PubMedCrossRef
20.
Basen-Enquist K, Carmack Taylor CL, Rosenblum C, et al. Randomized pilot test of a lifestyle physical activity intervention for breast cancer survivors. Patient Educ Couns. 2006; 64: 225–234.CrossRef
21.
McKenzie DC, Kalda AL. Effect of upper extremity exercise on secondary lymphedema in breast cancer patients: A pilot study. J Clin Oncol. 2003; 21: 463–466.PubMedCrossRef
22.
Sandel SL, Judge JO, Landry N, Faria L, Ouellette R, Majczak M. Dance and movement program improves quality-of-life measures in breast cancer survivors. Cancer Nurs. 2005; 28: 301–309.PubMedCrossRef
23.
Mock V, Frangakis C, Davidson NE, et al. Exercise manages fatigue during breast cancer treatment: A randomized controlled trial. Psychooncology. 2005; 14: 464–477.PubMedCrossRef
24.
Mock V, Pickett M, Ropka ME, et al. Fatigue and quality of life outcomes of exercise during cancer treatment. Cancer Pract. 2001; 9: 119–127.PubMedCrossRef
25.
Dzewaltowski DA, Estabrooks PA, Glasgow RE. The future of physical activity behavior change research: What is needed to improve translation of research into health promotion practice. Exerc Sport Sci Rev. 2004; 32: 57–63.PubMedCrossRef
26.
Patrick K, Scutchfield FD, Woolf SH. External validity reporting in prevention research. Am J Prev Med. 2008; 34: 260–262.PubMedCrossRef
27.
28.
Estabrooks P, Dzewaltowski DA, Glasgow RE, Klesges LM. Reporting of validity from school health promotion studies published in 12 leading journals, 1996–2000. J Sch Health. 2003; 73: 21–28.PubMedCrossRef
29.
Klesges LM, Dzewaltowski DA, Glasgow RE. Review of external validity reporting in childhood obesity prevention research. Am J Prev Med. 2008; 34: 216–223.PubMedCrossRef
30.
Dzewaltowski DA, Estabrooks PA, Klesges LM, Bull S, Glasgow RE. Behavior change intervention research in community settings: How generalizable are the results. Health Promot Int. 2004; 19: 235–245.PubMedCrossRef
31.
Victora CG, Habicht JP, Bryce J. Evidence-based public health: Moving beyond randomized trials. Am J Public Health. 2004; 94: 400–405.PubMedCrossRef
32.
Klesges LM, Estabrooks PA, Dzewaltowski DA, Bull SS, Glasgow RE. Beginning with the application in mind: Designing and planning health behavior change interventions to enhance dissemination. Ann Behav Med. 2005; 29: 66–75.PubMedCrossRef
33.
Vallance JKH, Courneya KS, Plotnikoff RC, Yasui Y, Mackey JR. Effects of print materials and step pedometers on physical activity and quality of life in breast cancer survivors: A randomized controlled trial. J Clin Oncol. 2007; 25: 2352–2359.PubMedCrossRef
34.
Marcus BH, Dubbert PM, Forsyth LH, et al. Physical activity behavior change: Issues in adoption and maintenance. Health Psychol. 2000; 19: 32–41.PubMedCrossRef
35.
Courneya KS, Friedenreich CM, Reid RD, et al. Predictors of follow-up exercise behavior 6 months after a randomized trial of exercise training during breast cancer chemotherapy. Breast Cancer Res Treat. 2009; 114: 179–187.PubMedCrossRef
36.
Altman DG, Schulz KF, Moher D, et al. The revised CONSORT statement for reporting randomized trials: Explanation and elaboration. Ann Intern Med. 2001; 134: 663–694.PubMed
37.
Moher D, Schulz KF, Altman DG. The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomized trials. J Am Podiatr Med Assoc. 2001; 91: 437–442.PubMed
38.
The Diabetes Prevention Program Research Group. The Diabetes Prevention Program (DPP): Description of lifestyle intervention. Diabetes Care. 2002; 25: 2165–2171.CrossRef
39.
The Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002; 346: 393–403.CrossRef
40.
The Diabetes Prevention Program Research Group. Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the Diabetes Prevention Program. Diabetes Care. 2005; 28: 888–894.CrossRef
41.
The Diabetes Prevention Program Research Group. Within-trial cost-effectiveness of lifestyle intervention or metformin for the primary prevention of type 2 diabetes. Diabetes Care. 2003; 26: 2518–2523.CrossRef
42.
Battaglini C, Bottaro M, Dennehy C, et al. The effects of an individualized exercise intervention on body composition in breast cancer patients undergoing treatment. Sao Paulo Med J. 2007; 125: 22–28.PubMedCrossRef
43.
Campbell A, Mutrie N, White F, McGuire F, Kearney N. A pilot study of a supervised group exercise program as a rehabilitation treatment for women with breast cancer receiving adjuvant treatment. Eur J Oncol Nurs. 2005; 9: 56–63.PubMedCrossRef
44.
Courneya KS, Mackey JR, Bell GJ, Jones LW, Field CJ, Fairey AS. Randomized controlled trial of exercise training in postmenopausal breast cancer survivors: Cardiopulmonary and quality of life outcomes. J Clin Oncol. 2003; 21: 1600–1668.CrossRef
45.
Culos-Reed SN, Carlson LE, Daroux LM, Hately-Aldous S. A pilot study of yoga for breast cancer survivors: Physical and psychological benefits. Psychooncology. 2006; 15: 891–897.PubMedCrossRef
46.
Drouin JS, Armstrong H, Krause S, Orr J. Effects of aerobic exercise training on peak aerobic capacity, fatigue, and psychological factors during radiation for breast cancer. Rehabilitation Oncology. 2005; 23: 11–17.
47.
Galantino ML, Capito L, Kane RJ, Ottey N, Switzer S, Packel L. The effects of tai chi and walking on fatigue and body mass index in women living with breast cancer: A pilot study. Rehabilitation Oncology. 2003; 21: 17–22.
48.
Headley JA, Ownby KK, John LD. The effect of seated exercise on fatigue and quality of life in women with advanced breast cancer. Oncol Nurs Forum. 2004; 31: 977–983.PubMedCrossRef
49.
Herrero F, San Juan AF, Fleck SJ, et al. Combined aerobic and resistance training in breast cancer survivors: A randomized, controlled pilot trial. Int J Sports Med. 2006; 27: 573–580.PubMedCrossRef
50.
Kim CJ, Kang DH, Smith BA, Landers KA. Cardiopulmonary responses and adherence to exercise in women newly diagnosed with breast cancer undergoing adjuvant therapy. Cancer Nurs. 2006; 29: 156–165.PubMedCrossRef
51.
Ligibel JA, Campbell N, Partridge A, et al. Impact of a mixed strength and endurance exercise intervention on insulin levels in breast cancer survivors. J Clin Oncol. 2008; 26: 907–912.PubMedCrossRef
52.
Milne HM, Wallman KE, Gordon S, Courneya KS. Effects of a combined aerobic and resistance exercise program in breast cancer survivors: A randomized controlled trial. Breast Cancer Res Treat. 2008; 108: 279–288.PubMedCrossRef
53.
Mustian KM, Katula JA, Gill DL, Roscoe JA, Lang D, Murphy K. Tai Chi Chuan, health-related quality of life and self-esteem: A randomized trial with breast cancer survivors. Support Care Cancer. 2004; 12: 871–876.PubMedCrossRef
54.
Mutrie N, Campbell AM, Whyte F, et al. Benefits of supervised group exercise programme for women being treated for early stage breast cancer: Pragmatic randomised controlled trial. BMJ. 2007; 334: 517–523.PubMedCrossRef
55.
Pinto BM, Clark MM, Maruyama NC, Feder SI. Psychological and fitness changes associated with exercise participation among women with breast cancer. Psychooncology. 2003; 12: 118–126.PubMedCrossRef
56.
Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH. Home-based physical activity intervention for breast cancer patients. J Clin Oncol. 2005; 20: 3577–3587.CrossRef
57.
Schmitz KH, Ahmed RL, Hannan PJ, Yee D. Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins. Cancer Epidemiol Biomarkers Prev. 2005; 14: 1672–1680.PubMedCrossRef
58.
Segal R, Evans W, Johnson D, et al. Structured exercise improves physical functioning in women with stages I and II breast cancer: Results of a randomized controlled trial. J Clin Oncol. 2001; 19: 657–665.PubMed
59.
Segar ML, Katch VL, Roth RS, et al. The effect of aerobic exercise on self-esteem and depressive and anxiety symptoms among breast cancer survivors. Oncol Nurs Forum. 1998; 25: 107–113.PubMed
Metadata
Title
Translating Physical Activity Interventions for Breast Cancer Survivors into Practice: An Evaluation of Randomized Controlled Trials
Authors
Siobhan M. White, B.S.
Edward McAuley, Ph.D.
Paul A. Estabrooks, Ph.D.
Kerry S. Courneya, Ph.D.
Publication date
01-02-2009
Publisher
Springer-Verlag
Published in
Annals of Behavioral Medicine / Issue 1/2009
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-009-9084-9

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