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Published in: Annals of Nuclear Medicine 3/2016

Open Access 01-04-2016 | Review Article

Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database

Authors: Kenichi Nakajima, Naoya Matsumoto, Tokuo Kasai, Shinro Matsuo, Keisuke Kiso, Koichi Okuda

Published in: Annals of Nuclear Medicine | Issue 3/2016

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Abstract

As a 2-year project of the Japanese Society of Nuclear Medicine working group activity, normal myocardial imaging databases were accumulated and summarized. Stress-rest with gated and non-gated image sets were accumulated for myocardial perfusion imaging and could be used for perfusion defect scoring and normal left ventricular (LV) function analysis. For single-photon emission computed tomography (SPECT) with multi-focal collimator design, databases of supine and prone positions and computed tomography (CT)-based attenuation correction were created. The CT-based correction provided similar perfusion patterns between genders. In phase analysis of gated myocardial perfusion SPECT, a new approach for analyzing dyssynchrony, normal ranges of parameters for phase bandwidth, standard deviation and entropy were determined in four software programs. Although the results were not interchangeable, dependency on gender, ejection fraction and volumes were common characteristics of these parameters. Standardization of 123I-MIBG sympathetic imaging was performed regarding heart-to-mediastinum ratio (HMR) using a calibration phantom method. The HMRs from any collimator types could be converted to the value with medium-energy comparable collimators. Appropriate quantification based on common normal databases and standard technology could play a pivotal role for clinical practice and researches.
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Metadata
Title
Normal values and standardization of parameters in nuclear cardiology: Japanese Society of Nuclear Medicine working group database
Authors
Kenichi Nakajima
Naoya Matsumoto
Tokuo Kasai
Shinro Matsuo
Keisuke Kiso
Koichi Okuda
Publication date
01-04-2016
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 3/2016
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-016-1065-z

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