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Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 10/2011

01-12-2011 | Invited review article

The molecular imaging approach to image infections and inflammation by nuclear medicine techniques

Authors: Alberto Signore, Andor W. J. M. Glaudemans

Published in: Annals of Nuclear Medicine | Issue 10/2011

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Abstract

Inflammatory and infectious diseases are a heterogeneous class of diseases that may be divided into infections, acute inflammation and chronic inflammation. Radiological imaging techniques have, with the exception of functional MRI, high sensitivity but lack in specificity. Nuclear medicine techniques, by contrast, allow the in vivo detection in humans of different physiologic and pathologic phenomena and offer noninvasive tools to detect early pathophysiological changes before anatomical changes occur. In this review, we highlight the role of nuclear medicine in inflammation/infection with emphasis on molecular imaging for in vivo histological characterization of affected tissues for diagnostic purposes and follow-up of therapies. We also describe the clinical indications of all available radiopharmaceuticals in the light of the newly available guidelines.
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Metadata
Title
The molecular imaging approach to image infections and inflammation by nuclear medicine techniques
Authors
Alberto Signore
Andor W. J. M. Glaudemans
Publication date
01-12-2011
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 10/2011
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-011-0521-z

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