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Head and Neck Pathology
Published in: Head and Neck Pathology 4/2022

14-07-2022 | Sine qua non Radiology-Pathology

Sine Qua Non: Oncocytoma

Authors: Robert D. Rivera, Brenda L. Nelson

Published in: Head and Neck Pathology | Issue 4/2022

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Abstract

Oncocytomas of the salivary gland are uncommon neoplasms that are characterized by polygonal cells with abundant granular eosinophilic cytoplasm and relatively uniform nuclei. They are benign in nature and have a low recurrence rate with complete surgical excision. Though uncommon, oncocytic and clear cell variants of malignant tumors may histologically mimic oncocytomas and identification of their distinguishing features is essential. A classic example of an oncocytoma is discussed.
Literature
1.
Richardson MS. 12 - Benign Neoplasms of the Salivary Glands. In Thompson LDR, Bishop JA, eds. Head and Neck Pathology (Third Edition). Philadelphia: Elsevier, 2019; 261–283.e2.
2.
Zhou C-X, Gao Y. Oncocytoma of the salivary glands: A clinicopathologic and immunohistochemical study. Oral Oncol. 2009;45:e232–8.CrossRef
3.
El-Naggar AK, Chan JKC, Grandis JR et al, editors. WHO Classification of Head and Neck Tumours. 4th ed. Vol. 9: International Agency for Research on Cancer; 2017.
4.
Sepúlveda I, Platín E, Spencer ML, et al. Oncocytoma of the Parotid Gland:A Case Report and Review of the Literature. Case Rep Oncol. 2014;7:109–16.CrossRef
5.
Popovski V, Benedetti A, Monevska DP, et al. Oncocytoma of the Deep Lobe of the Parotid Gland. Open Access Maced J Med Sci. 2016;4:290–2.CrossRef
6.
Korbi AE, Jellali S, Njima M, et al. Parotid Gland Oncocytoma: A Rare Case and Literature Review. J Med Cases. 2019;10:146–9.CrossRef
7.
Akhtar K, Qadri S, Ray PS, et al. Oncocytoma of the parotid gland: Dilemma for the cytopathologist. J Orofac Sci. 2016;8:5.
8.
Capone RB, Ha PK, Westra WH, et al. Oncocytic Neoplasms of the Parotid Gland: A 16-Year Institutional Review. Otolaryngol Neck Surg. 2002;126:657–62.CrossRef
9.
Nikolopoulos E, Ploumidou K, Gazalidou M, et al. A rare case of oncocytoma of the parotid gland with aggresssive features and malignant potential: a case report. J Otolaryngol-ENT Res 2018; Volume 10.
10.
Lee W-Y, Chang S-L. Fine needle aspiration cytology of oncocytic carcinoma of the submandibular gland with pre-existing oncocytoma: a case report. Cytopathology. 2010;21:339–41.CrossRef
11.
Lee T-H, Lin Y-S, Lee W-Y, et al. Malignant Transformation of a Benign Oncocytoma of the Submandibular Gland: A Case Report. Kaohsiung J Med Sci. 2010;26:327–32.CrossRef
12.
Laurian N, Zohar Y, Kende L. Malignant oncocytoma. J Laryngol Otol. 1977;91:805–8.CrossRef
13.
Thompson LD, Wenig BM, Ellis GL. Oncocytomas of the submandibular gland: A series of 22 cases and a review of the literature. Cancer. 1996;78:2281–7.CrossRef
14.
Hamada S, Fujiwara K, Hatakeyama H, et al. Oncocytoma of the Parotid Gland with Facial Nerve Paralysis. Case Rep Otolaryngol 2018.
15.
Tan TJ, Tan TY. CT Features of Parotid Gland Oncocytomas: A Study of 10 Cases and Literature Review. Am J Neuroradiol. 2010;31:1413–7.CrossRef
16.
Lubin D, Song S, Zafar HM, et al. The key radiologic and cytomorphologic features of oncocytic and oncocytoid lesions of the salivary gland. Diagn Cytopathol. 2019;47:617–36.CrossRef
17.
Sanjive JG, Reddy NS, Soundara Rajan V. Oncocytoma: a mystifying parotid mass. Int Surg J. 2019;6:1418.CrossRef
18.
Patel ND, Zante A van, Eisele DW, et al. Oncocytoma: The Vanishing Parotid Mass. Am J Neuroradiol. 2011;32:1703–6.CrossRef
19.
Imran S, Allen A, Shokouh-Amiri M, et al. Parotid oncocytoma: CT and pathologic correlation of a rare benign parotid tumor. Radiol Case Rep. 2019;15:31–4.CrossRef
20.
Shellenberger TD, Williams MD, Clayman GL, et al. Parotid Gland Oncocytosis: CT Findings with Histopathologic Correlation. Am J Neuroradiol. 2008;29:734–6.CrossRef
21.
Abdel Razek AAK, Mukherji SK. State-of-the-Art Imaging of Salivary Gland Tumors. Neuroimaging Clin N Am. 2018;28:303–17.CrossRef
22.
Özcan C, Talas D, Görür K, et al. Incidental deep lobe parotid gland oncocytic neoplasms in an operated larynx cancer patient. Oral Oncol Extra. 2006;42:235–40.CrossRef
23.
Kato H, Fujimoto K, Matsuo M, et al. Usefulness of diffusion-weighted MR imaging for differentiating between Warthin’s tumor and oncocytoma of the parotid gland. Jpn J Radiol. 2017;35:78–85.CrossRef
24.
Chen B, Hentzelman JI, Walker RJ, et al. Oncocytoma of the Submandibular Gland: Diagnosis and Treatment Based on Clinicopathology. Case Rep Otolaryngol 2016.
25.
Hoda SA, Patel A. Rosai and Ackerman’s Surgical Pathology. Am J Clin Pathol. 2018;149:548–8.CrossRef
26.
Hung L. Oncocytic Mucoepidermoid Carcinoma: A Case Report. 2019; 4:4.
Metadata
Title
Sine Qua Non: Oncocytoma
Authors
Robert D. Rivera
Brenda L. Nelson
Publication date
14-07-2022
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 4/2022
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-022-01462-5

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