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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2013

01-03-2013 | Sine qua non Clinicopathologic Correlat

Nonkeratinizing Undifferentiated Nasopharyngeal Carcinoma

Authors: Brandon R. Peterson, Brenda L. Nelson

Published in: Head and Neck Pathology | Issue 1/2013

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Excerpt

A 74-year-old Asian female presented to her primary care physician with a 3-month history of cough, rhinorrhea, and post-nasal drip. Physical examination revealed the presence of bilateral firm, fixed, non-tender anterior cervical masses. The patient was treated for rhinosinusitis while radiographic studies were obtained. …
Literature
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Pathmanathan R, Prasad U, Chandrika G, et al. Undifferentiated, nonkeratinizing, and squamous cell carcinoma of the nasopharynx. Variants of Epstein–Barr virus-induced neoplasia. Am J Pathol. 1995;146:1355–67.PubMed
2.
Poirier S, Ohshima H, de The G, Hubert A, Bourgade MC, Bartsch H. Volatile nitrosamine levels in common foods from Tunisia, South China and Greenland, high-risk areas for nasopharyngeal carcinoma (NPC). Int J Cancer. 1987;39:293–6.PubMedCrossRef
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Nicholls JM, Agathanggelou A, Fung K, et al. The association of squamous cell carcinomas of the nasopharynx with Epstein–Barr virus shows geographical variation reminiscient of Burkitt’s lymphoma. J Pathol. 1997;183:164–8.PubMedCrossRef
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Slootweg PJ, Richardson M. Squamous cell carcinoma of the upper aerodigestive system. In: Gnepp DR, editor. Diagnostic surgical pathology of the head and neck. 2nd ed. Philadelphia: Elsevier; 2009. p. 54–7.
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Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. Lyon: IARC Press; 2005.
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Shanmugaratnam K, Chan SH, de The G, et al. Histopathology of nasopharyngeal carcinoma. Correlations with epidemiology, survival rates, and other biological characteristics. Cancer. 1979;44:1029–44.PubMedCrossRef
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Fandi A, Cvitkovic E. Biology and treatment of nasopharyngeal cancer. Curr Opin Oncol. 1995;7:255–63.PubMedCrossRef
Metadata
Title
Nonkeratinizing Undifferentiated Nasopharyngeal Carcinoma
Authors
Brandon R. Peterson
Brenda L. Nelson
Publication date
01-03-2013
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2013
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-012-0401-4

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