Published in:
01-12-2009 | Original Paper
Salivary Gland Tumor: A Review of 599 Cases in a Brazilian Population
Authors:
Flávia Aparecida de Oliveira, Eliza Carla Barroso Duarte, Cláudia Teixeira Taveira, Aline Abreu Máximo, Érica Carvalho de Aquino, Rita de Cássia Alencar, Eneida Franco Vencio
Published in:
Head and Neck Pathology
|
Issue 4/2009
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Abstract
Salivary gland tumors consist of a group of heterogeneous lesions with complex clinicopathological characteristics and distinct biological behaviors. Worldwide series show a contrast in the relative incidence of salivary gland tumors, with some discrepancies in clinicopathological data. The main aim of this study was to describe demographic characteristics of 599 cases in a population from Central Brazil over a 10-year period and compare these with other epidemiological studies. Benign tumors represented 78.3% of the cases. Women were the most affected (61%) and the male:female ratio was 1:1.6. Parotid gland tumors were the most frequent (68.5% of cases) and patient age ranged from 1 to 88 years-old (median of 45 years old). The most frequent tumors were pleomorphic adenomas (68.4%) and benign tumors were significantly more frequent in the parotid (75.9%), while malignant tumors were more frequent in the minor salivary glands (40%) (P < 0.05). In conclusion, women and the parotid gland were the most affected and pleomorphic adenoma was the most frequent lesion, followed by adenoid cystic carcinoma and Warthin’s tumor.