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Head and Neck Pathology
Published in: Head and Neck Pathology 4/2008

01-12-2008 | Case report

Primary Unilateral Multifocal Pleomorphic Adenoma of the Parotid Gland: Molecular Assessment and Literature Review

Authors: John R. Miliauskas, Jennifer L. Hunt

Published in: Head and Neck Pathology | Issue 4/2008

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Abstract

Multiple separate tumors developing in a single salivary gland is rare in previously untreated patients. Tumors that can be multicentric include Warthin tumor, oncocytoma, basal cell adenoma and acinic cell carcinoma. The incidence of multiple primary unilateral pleomorphic adenomas is extremely rare in patients with no prior history of trauma or surgery. We report two cases of primary multicentric pleomorphic adenoma and review the literature. We also subjected one of our cases to a molecular clonality test. The molecular results suggested that the separate nodules were clonally related, arguing against an independent origin.
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Metadata
Title
Primary Unilateral Multifocal Pleomorphic Adenoma of the Parotid Gland: Molecular Assessment and Literature Review
Authors
John R. Miliauskas
Jennifer L. Hunt
Publication date
01-12-2008
Publisher
Humana Press Inc
Published in
Head and Neck Pathology / Issue 4/2008
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-008-0081-2

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