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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 1/2021

01-01-2021 | Scientific Letter

Successful Treatment of Collodion Baby with Acitretin: A Report of Two Cases

Authors: Deepika Kainth, Dhirendra Prasad Yadav, Savera Gupta, Bhavya Swarnkar, Ankit Verma, Ramesh Agarwal, Gomathy Sethuraman

Published in: Indian Journal of Pediatrics | Issue 1/2021

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Excerpt

To the Editor: Collodion baby, a phenotypic diagnosis in a newborn, is covered with a parchment-like membrane all over the body. In some babies, the epidermal barrier is severely impaired leading to an increase in transepidermal water loss (TEWL), hypernatremic dehydration, poor feeding, failure to thrive and infections [1, 2]. In this report we describe two babies with collodion membrane, successfully treated with oral acitretin and other supportive measures. …
Literature
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Vahlquist A, Gånemo A, Virtanen M. Congenital ichthyosis: an overview of current and emerging therapies. Acta Derm Venereol. 2008;88:4–14.CrossRef
2.
Prado R, Ellis LZ, Gamble R, Funk T, Arbuckle HA, Bruckner AL. Collodion baby: an update with a focus on practical management. J Am Acad Dermatol. 2012;67:1362–74.CrossRef
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Nguyen MA, Gelman A, Norton SA. Practical events in the management of a collodion baby. JAMA Dermatol. 2015;151:1031–2.CrossRef
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Glick JB, Craiglow BG, Choate KA, et al. Improved management of harlequin ichthyosis with advances in neonatal intensive care. Pediatrics. 2017;139:e20161003.CrossRef
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Damodaran K, Bhutada A, Rastogi S. A unique preparation and delivery method for acitretin for neonatal harlequin ichthyosis. J Pediatr Pharmacol Ther. 2018;23:164–7.PubMedPubMedCentral
Metadata
Title
Successful Treatment of Collodion Baby with Acitretin: A Report of Two Cases
Authors
Deepika Kainth
Dhirendra Prasad Yadav
Savera Gupta
Bhavya Swarnkar
Ankit Verma
Ramesh Agarwal
Gomathy Sethuraman
Publication date
01-01-2021
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 1/2021
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-020-03474-x

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