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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 1/2019

01-01-2019 | Review Article

Bacterial Infections of the Central Nervous System

Authors: Renu Suthar, Naveen Sankhyan

Published in: Indian Journal of Pediatrics | Issue 1/2019

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Abstract

Bacterial infections of the central nervous system (CNS) continue to be an important cause of morbidity and mortality in children. The spectrum of bacterial infection of CNS includes; focal or multifocal infections like brain abscesses or subdural empyema; or more generalized or diffuse infections like pyogenic meningitis or ventriculitis. Focal and generalized infections may co-exist in an individual patient. Prompt and adequate antibiotic therapy and occasionally neurosurgical interventions are the cornerstone of effective management. The recent emergence of several multidrug-resistant bacteria poses a threat to the effective management of bacterial CNS infections. Several adjunctive anti-inflammatory and neuroprotective therapies are being tried, however; none has made a remarkable impact on the outcome. Consequently, bacterial CNS infections in children still remain a challenge to manage. In this review, authors discuss the current updates on the diagnostic and therapeutic aspects of bacterial infections of the CNS in children (post-neonatal age group).
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Metadata
Title
Bacterial Infections of the Central Nervous System
Authors
Renu Suthar
Naveen Sankhyan
Publication date
01-01-2019
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 1/2019
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-017-2477-z

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