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01-10-2017 | Editorial Commentary

Hepcidin and Thalassemia

Author: Deepak Bansal

Published in: Indian Journal of Pediatrics | Issue 10/2017

Excerpt

This issue of the journal carries a study that has investigated the role of serum hepcidin as a diagnostic tool for measuring iron overload in patients with β-thalassemia major [1]. …

Kaddah AM, Abdel-Salam A, Farhan MS, Ragab R. Serum hepcidin as a diagnostic marker of severe iron overload in beta-thalassemia major. Indian J Pediatr. 2017; doi:10.1007/s12098-017-2375-4.

Pasricha SR, Frazer DM, Bowden DK, Anderson GJ. Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: a longitudinal study. Blood. 2013;122:124–33.CrossRefPubMed

Nemeth E. Hepcidin and β-thalassemia major. Blood. 2013;122:3–4.CrossRefPubMed

Haghpanah S, Esmaeilzadeh M, Honar N, et al. Relationship between serum hepcidin and ferritin levels in patients with thalassemia major and intermedia in southern Iran. Iran Red Crescent Med J. 2015;17:e28343.CrossRefPubMedPubMedCentral

Camaschella C, Schrier SL. Regulation of iron balance. In: Mentzer WC, Tirnauer JS, editors. Waltham: UpToDate. Available at: https://www.uptodate.com/contents/regulation-of-iron-balance. Accessed 19 July 2017.

Girelli D, Nemeth E, Swinkels DW. Hepcidin in the diagnosis of iron disorders. Blood. 2016;127:2809–13.CrossRefPubMedPubMedCentral

Nemeth E. Hepcidin in beta-thalassemia. Ann N Y Acad Sci. 2010;1202:31–5.CrossRefPubMedPubMedCentral

Mandal S, Sodhi KS, Bansal D, et al. MRI for quantification of liver and cardiac iron in thalassemia major patients: pilot study in Indian population. Indian J Pediatr. 2017;84:276–82.CrossRefPubMed

Title: Hepcidin and Thalassemia
Author: Deepak Bansal
Publication date: 01-10-2017
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 10/2017
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-017-2439-5

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