Skip to main content
Top
Published in: Indian Journal of Pediatrics 6/2016

01-06-2016 | Editorial Commentary

Arterial Compliance in Obesity- A Valuable Tool or Opening Up a Pandora’s Box?

Author: Anurag Bajpai

Published in: Indian Journal of Pediatrics | Issue 6/2016

Login to get access

Excerpt

Childhood obesity has emerged as a new age epidemic with significant short and long term implications. Given the association of childhood obesity with complications like insulin resistance, dyslipidemia and hypertension it is likely that obese children are at a substantial cardiovascular risk as adults. Timely identification of children at risk to cardiovascular complications is important for targeted preventive strategies. An ideal tool to assess long term cardiovascular risk in obese children should be easy to use, reproducible and able to predict long term adverse cardiovascular outcomes. Reduced arterial compliance measured by pulse wave form or peak wave velocity in central and peripheral circulation has been associated with obesity and cardiovascular risk in adults [1]. The validity for the same in children is not yet established. …
Literature
1.
go back to reference Acree LS, Montgomery PS, Gardner AW. The influence of obesity on arterial compliance in adult men and women. Vasc Med. 2007;12:183–8.CrossRefPubMed Acree LS, Montgomery PS, Gardner AW. The influence of obesity on arterial compliance in adult men and women. Vasc Med. 2007;12:183–8.CrossRefPubMed
3.
go back to reference Tounian P, Aggoun Y, Dubern B, et al. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet. 2001;358:1400–4.CrossRefPubMed Tounian P, Aggoun Y, Dubern B, et al. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet. 2001;358:1400–4.CrossRefPubMed
4.
go back to reference Sakuragi S, Abhayaratna K, Gravenmaker KJ, et al. Influence of adiposity and physical activity on arterial stiffness in healthy children: the lifestyle of our kids study. Hypertension. 2009;53:611–6.CrossRefPubMed Sakuragi S, Abhayaratna K, Gravenmaker KJ, et al. Influence of adiposity and physical activity on arterial stiffness in healthy children: the lifestyle of our kids study. Hypertension. 2009;53:611–6.CrossRefPubMed
5.
go back to reference Tryggestad JB, Thompson DM, Copeland KC, Short KR. Obese children have higher arterial elasticity without a difference in endothelial function: the role of body composition. Obesity. 2012;20:165–71.CrossRefPubMed Tryggestad JB, Thompson DM, Copeland KC, Short KR. Obese children have higher arterial elasticity without a difference in endothelial function: the role of body composition. Obesity. 2012;20:165–71.CrossRefPubMed
6.
go back to reference Donald AE, Charakida M, Falaschetti E, et al. Determinants of vascular phenotype in a large childhood population: the Avon longitudinal study of parents and children (ALSPAC). Eur Heart J. 2010;31:1502–10.CrossRefPubMedPubMedCentral Donald AE, Charakida M, Falaschetti E, et al. Determinants of vascular phenotype in a large childhood population: the Avon longitudinal study of parents and children (ALSPAC). Eur Heart J. 2010;31:1502–10.CrossRefPubMedPubMedCentral
7.
go back to reference Dangardt F, Osika W, Volkmann R, Gan LM, Friberg P. Obese children show increased intimal wall thickness and decreased pulse wave velocity. Clin Physiol Funct Imaging. 2008;28:287–93.CrossRefPubMed Dangardt F, Osika W, Volkmann R, Gan LM, Friberg P. Obese children show increased intimal wall thickness and decreased pulse wave velocity. Clin Physiol Funct Imaging. 2008;28:287–93.CrossRefPubMed
8.
go back to reference Chalmers LJ, Copeland KC, Hester C, Fields DA, Gardner AW. Paradoxical increase in arterial compliance in overweight pubertal children. Angiology. 2011;62:565–70.CrossRefPubMed Chalmers LJ, Copeland KC, Hester C, Fields DA, Gardner AW. Paradoxical increase in arterial compliance in overweight pubertal children. Angiology. 2011;62:565–70.CrossRefPubMed
9.
Metadata
Title
Arterial Compliance in Obesity- A Valuable Tool or Opening Up a Pandora’s Box?
Author
Anurag Bajpai
Publication date
01-06-2016
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 6/2016
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-016-2118-y

Other articles of this Issue 6/2016

Indian Journal of Pediatrics 6/2016 Go to the issue