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01-05-2015 | Editorial Commentary

Probiotics in Pediatrics

Authors: Meenakshi Bothra, Shinjini Bhatnagar

Published in: Indian Journal of Pediatrics | Issue 5/2015

Excerpt

Probiotics refer to the live microorganisms which, when ingested in an adequate amount, provide health benefit to the host. Most of the probiotics are bacteria, while Saccharomyces boulardii is a yeast [1]. The postulated mechanisms by which probiotics exert their beneficial effects include improvement in host barrier function, competitive inhibition of pathogenic bacteria, strengthening of tight junctions between enterocytes, promoting maturation of the intestinal brush border membrane and stimulation of production of secretory IgA. …

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Sur D, Manna B, Niyogi SK, Ramamurthy T, Palit A, Nomoto K, et al. Role of probiotic in preventing acute diarrhoea in children: a community-based, randomized, double-blind placebo-controlled field trial in an urban slum. Epidemiol Infect. 2011;139:919–26.CrossRefPubMed

Hegar B, Waspada MI, Gunardi H, Vandenplas Y. A double blind randomized trial showing probiotics to be ineffective in acute diarrhea in Indonesian children. Indian J Pediatr. 2014. doi:10.1007/s12098-014-1408-5.PubMed

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Title: Probiotics in Pediatrics
Authors: Meenakshi Bothra
Shinjini Bhatnagar
Publication date: 01-05-2015
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 5/2015
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-015-1719-1

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Probiotics in Pediatrics

Excerpt

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