Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 4/2015

01-04-2015 | Original Article

Does Type of Feeding in Infancy Influence Lipid Profile in Later Life?

Authors: Devender Chhonker, M. M. A. Faridi, Manish Narang, S. B. Sharma

Published in: Indian Journal of Pediatrics | Issue 4/2015

Login to get access

Abstract

Objective

To compare the lipid profile of exclusively breastfed and mixed-fed, term, appropriate for gestation age infants from 6 mo to 1 y of age.

Methods

This prospective comparative study included one hundred ninety nine consecutive term healthy infants; 105 on exclusive breastfeeding (EBF) and 94 receiving mixed feeding (MF). These children were recruited at 6 mo of age and followed till 1 y of age. Serum lipid levels of babies were determined at recruitment (6 mo), 9 mo and 1 y of age. Statistical analysis was carried out using SPSS software.

Results

The mean total cholesterol (TC) at 6 mo in exclusively breastfed group (156.38 ± 50.42 mg/dl) was significantly higher than mixed fed group (139.5 ± 37.59 mg/dl). At 9 mo, high density lipoprotein cholesterol (HDL-C) and triglycerides (TG) levels were significantly different in EBF group than MF group. The lipid profile of both group of babies was comparable at 1 y of age. The HDL-C: LDL-C ratio was significantly different between the two groups (higher in breastfed group) at 1 y.

Conclusions

The present study highlights differential lipid profile of exclusively breastfed infants and mixed fed infants.
Literature
1.
Kaur S, Kapil U. Dyslipidemia amongst obese children in national capital territory (NCT) of Delhi. Indian J Pediatr. 2011;78:55–7.CrossRefPubMed
2.
Ghayour-Mobarhan M, Sahebkar A, Vakili R, Safarian M, Nematy M, Lotfian E. Investigation of the effect of high dairy diet on body mass index and body fat in overweight and obese children. Indian J Pediatr. 2009;76:1145–50.CrossRefPubMed
3.
Marmot MG, Page CM, Atkins E, Douglas JW. Effect of breastfeeding onplasma cholesterol and weight in young adults. J Epidemiol Community Health. 1980;34:164–7.CrossRefPubMedCentralPubMed
4.
Singhal A, Cole TJ, Lucas A. Early nutrition in preterm infants and later bloodpressure: two cohorts after randomized trials. Lancet. 2001;357:413–9.CrossRefPubMed
5.
Ravelli AC, Van der Meulen JH, Osmond C, Barker DJ, Bleker OP. Infantfeeding and adult glucose tolerance, lipid profile, blood pressure and obesity. Arch Dis Child. 2000;82:248–52.CrossRefPubMedCentralPubMed
6.
Harit D, Faridi MMA, Aggarwal A, Sharma SB. Lipid profile of term infants onexclusive breast-feeding and mixed feeding. A comparative study. Eur J Clin Nutr. 2008;62:203–9.CrossRefPubMed
7.
Agostoni C, Riva E, Scaglioni S, Marangoni F, Radaelli G, Giovannini M. Dietary fats and cholesterol in Italian infants and children. Am J Clin Nutr. 2000;72:1384S–91.PubMed
8.
Sveger T, Lindberg T, Weibull B, Olsson UL. Nutrition, overnutrition andobesity in the first year of life in Malmo, Sweden. Acta Paediatr Scand. 1975;64:635–40.CrossRefPubMed
9.
Friedman G, Goldberg SJ. Concurrent and subsequent serum cholesterols ofbreastfed and formula-fed infants. Am J Clin Nutr. 1975;28:42–5.PubMed
10.
Van Biervliet JP, Rosseneu M, Caster H. Influence of dietary factors on theplasma lipoprotein composition and content in neonates. Eur J Pediatr. 1986;144:489–93.CrossRefPubMed
11.
Jooste PL, Rossouw LJ, Steenkamp HJ, Rossouw JE, Swanepoel AS, Charlto DO. Effect of breast feeding on the plasma cholesterol and growth ofinfants. J Pediatr Gastroenterol Nutr. 1991;13:139–42.CrossRefPubMed
12.
Akeson PM, Axelsson IE, Raiha NC. Plasma lipids and apolipoproteins inbreastfed and formula-fed Swedish infants. Acta Paediatr. 1999;88:1–6.CrossRefPubMed
13.
Spady DK, Dietschy JM. Dietary saturated triacylglycerols suppress hepaticlow density lipoprotein receptor activity in the hamster. Proc Natl Acad Sci. 1985;82:4526–30.CrossRefPubMedCentralPubMed
14.
Kallio MJ, Salmeapera L, Simes MA, Perheentupa J, Miettinen TA. Exclusivebreast feeding and weaning: effect on serum cholesterol and lipoproteinconcentrations in infants during the first year of life. Pediatrics. 1992;89:663–6.PubMed
Metadata
Title
Does Type of Feeding in Infancy Influence Lipid Profile in Later Life?
Authors
Devender Chhonker
M. M. A. Faridi
Manish Narang
S. B. Sharma
Publication date
01-04-2015
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 4/2015
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-014-1580-7

Other articles of this Issue 4/2015

Indian Journal of Pediatrics 4/2015 Go to the issue

Original Article

A Cervical Flexion-Extension MRI Study in Down Syndrome

Scientific Letter

Two Brothers with Multiple Cranial Nerve Palsies

Picture of the Month

An Unusual Case of Encephalitis with Starry Sky Pattern in MRI

Editorial Commentary

Audit of Pediatric Transfusion Practices: A Commentary

Original Article

Meningitis Related Ventriculitis - Experience from a Tertiary Care Centre in Northern India

Original Article

Efficacy of Nebulised Budesonide versus Oral Prednisolone in Acute Severe Asthma