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01-04-2013 | Commentary

Status and Current Role of ‘Interferon Gamma Release Assays’ vs. ‘Tuberculin Skin Testing’ in Diagnosis of Tubercular Disease

Authors: Aparna Mukherjee, Rakesh Lodha, S. K. Kabra

Published in: Indian Journal of Pediatrics | Issue 4/2013

Excerpt

Childhood tuberculosis is a common cause of morbidity and mortality in developing countries. In 2011, there were an estimated 8.7 million incident cases of tuberculosis globally, out of which about half a million were children [1]. …

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Metcalfe JZ, Everett CK, Steingart KR, et al. Interferon-γ release assays for active pulmonary tuberculosis diagnosis in adults in low- and middle-income countries: systematic review and meta-analysis. J Infect Dis. 2011;204:S1120–29.PubMedCrossRef

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Dheda K, Van ZylSmit R, Badri M, Pai M. T-cell interferon-gamma release assays for the rapid immunodiagnosis of tuberculosis: clinical utility in high-burden vs. low-burden settings. Curr Opin Pulm Med. 2009;15:188–200.PubMedCrossRef

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World Health Organization. New WHO recommendations on use of commercial TB Interferon-Gamma Release Assays (IGRAs) in low- and middle-income countries [Internet]. WHO 2011. Available from: http://www.who.int/tb/features_archive/igra_policy24oct/en/index.html. Accessed on: 30.11.12

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Piñeiro R, Cilleruelo MJ, García-Hortelano M, García-Ascaso M, Medina-Claros A, Mellado MJ. Effect of nutritional status on tuberculin skin testing. Indian J Pediatr. 2012; doi:10.1007/s12098-012-0773-1.

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Chauhan S, Gahalaut P, Rathi AK. Tuberculin skin test, chest radiography and contact screening in children ≤5 Y: Relevance in revised National Tuberculosis Control Programme (RNTCP). Indian J Pediatr. 2012; doi:10.1007/s12098-012-0792-y.

Title: Status and Current Role of ‘Interferon Gamma Release Assays’ vs. ‘Tuberculin Skin Testing’ in Diagnosis of Tubercular Disease
Authors: Aparna Mukherjee
Rakesh Lodha
S. K. Kabra
Publication date: 01-04-2013
Publisher: Springer-Verlag
Published in: Indian Journal of Pediatrics / Issue 4/2013
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-013-0974-2

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Status and Current Role of ‘Interferon Gamma Release Assays’ vs. ‘Tuberculin Skin Testing’ in Diagnosis of Tubercular Disease

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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Evaluation of Predictors of Adverse Outcome in Febrile Neutropenic Episodes in Pediatric Oncology Patients

Prevalence of Congenital Heart Disease

Management of a Child with Vomiting

Tuberculin Skin Test, Chest Radiography and Contact Screening in Children ≤5 Y: Relevance in Revised National Tuberculosis Control Programme (RNTCP)

Effect of Nutritional Status on Tuberculin Skin Testing

Prevalence, Pattern and Outcome of Congenital Heart Disease in Bhabha Atomic Research Centre Hospital, Mumbai