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Published in: Indian Journal of Pediatrics 4/2013

01-04-2013 | Original Article

Prevalence, Pattern and Outcome of Congenital Heart Disease in Bhabha Atomic Research Centre Hospital, Mumbai

Authors: Sangeeta Priyadarshi Sawant, Alpa Sanjeev Amin, Minakshi Bhat

Published in: Indian Journal of Pediatrics | Issue 4/2013

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Abstract

Objective

To assess the prevalence, pattern and outcome of congenital heart disease (CHD) among the babies born in Bhabha Atomic Research Centre (BARC) Hospital, Mumbai and to compare the pattern of CHD with the study done in the same hospital in year 1999.

Methods

A prospective, longitudinal study was conducted from January 2006 through December 2011. Babies presenting with murmur were closely followed up till the diagnosis and further to assess the outcome. 2-D Echocardiography was used as a diagnostic tool.

Results

The overall prevalence of CHD was 13.28 per 1,000 live births. Ventricular septal defect (VSD) was the commonest CHD (42.86 %) followed by Atrial septal defect (ASD) (25.71 %) giving the prevalence of 5.69 and 3.41 per 1,000 live births respectively. Tetrology of Fallot’s (TOF) was the main cyanotic CHD (8.57 %) with the prevalence of 1.13 per 1,000 live births. VSD and TOF were prevalent in males. ASD was prevalent in females. Associated structural anomalies were detected in 22.86 % cases; Down’s syndrome being the commonest.Spontaneous closure rate of 71.4 % in muscular VSD and 50 % in perimembranous VSD was observed. All small sized VSD’s closed spontaneously and all large sized VSD’s required surgical intervention. Spontaneous closure was observed in 44.44 % of ASD cases. Overall, device closure was required in 17.14 % and 25.71 % underwent open heart surgery.

Conclusions

The pattern of CHD has remained almost the same compared to the previous study. The outcome was excellent due to early diagnosis, regular follow up and timely intervention.
Literature
1.
go back to reference Kapoor R, Gupta S. Prevalence of congenital heart disease, Kanpur, India. Indian Pediatr. 2008;45:309–11.PubMed Kapoor R, Gupta S. Prevalence of congenital heart disease, Kanpur, India. Indian Pediatr. 2008;45:309–11.PubMed
2.
go back to reference Mishra M, Mittal M, Verma AM, et al. Prevalence and pattern of congenital heart disease in school children of Eastern Uttar Pradesh. Indian Heart J. 2009;61:58–60. Mishra M, Mittal M, Verma AM, et al. Prevalence and pattern of congenital heart disease in school children of Eastern Uttar Pradesh. Indian Heart J. 2009;61:58–60.
3.
go back to reference Bidwai PS, Mahajan CM, Walia BN, Berry JN. Congenital heart diseases in childhood – A clinical study. Indian Pediatr. 1971;10:691–4. Bidwai PS, Mahajan CM, Walia BN, Berry JN. Congenital heart diseases in childhood – A clinical study. Indian Pediatr. 1971;10:691–4.
4.
go back to reference Manchanda SS, Sachdev KK. Morbidity and mortality in children in Northern India (Punjab). Indian J Pediatr. 1962;29:333–50.PubMedCrossRef Manchanda SS, Sachdev KK. Morbidity and mortality in children in Northern India (Punjab). Indian J Pediatr. 1962;29:333–50.PubMedCrossRef
5.
go back to reference Gupta S, Puri RK, Indira OC, Datta SP. Morbidity in children under 14 in South India. Indian Pediatr. 1968;5:485–97.PubMed Gupta S, Puri RK, Indira OC, Datta SP. Morbidity in children under 14 in South India. Indian Pediatr. 1968;5:485–97.PubMed
6.
7.
go back to reference Ferencz C, Rubin JD, Mc Carter RJ, et al. Congenital heart disease: prevalence at live birth. The Baltimore- Washington infant study. Am J Epidemiol. 1985;121:31–6.PubMed Ferencz C, Rubin JD, Mc Carter RJ, et al. Congenital heart disease: prevalence at live birth. The Baltimore- Washington infant study. Am J Epidemiol. 1985;121:31–6.PubMed
8.
go back to reference Bollistey S, Daftary A, Ewald D, et al. Congenital heart defets in central Australia. Med J. 2004;180:614–7. Bollistey S, Daftary A, Ewald D, et al. Congenital heart defets in central Australia. Med J. 2004;180:614–7.
9.
go back to reference Kasturi L, Amin A, Mashankar VA. Congenital heart disease: clinical spectrum. Indian Pediatr. 1999;36:953.PubMed Kasturi L, Amin A, Mashankar VA. Congenital heart disease: clinical spectrum. Indian Pediatr. 1999;36:953.PubMed
10.
go back to reference Smitha R, Karat SC, Narayanappa D, Krishnamurthy B, Prasanth SN, Ramchandra NB. Prevalence of congenital heart disease in Mysore. Indian J Hum Genet. 2006;12:11–6.CrossRef Smitha R, Karat SC, Narayanappa D, Krishnamurthy B, Prasanth SN, Ramchandra NB. Prevalence of congenital heart disease in Mysore. Indian J Hum Genet. 2006;12:11–6.CrossRef
12.
go back to reference Chadha SL, Singh N, Shukla DK. Epidemiological study of congenital heart disease. Indian J Pediatr. 2001;68:507–10.PubMedCrossRef Chadha SL, Singh N, Shukla DK. Epidemiological study of congenital heart disease. Indian J Pediatr. 2001;68:507–10.PubMedCrossRef
13.
go back to reference Sharmin LS, Haque MA, Bari MI, Ali MA. Pattern and clinical profile of congenital heart disease in a teaching hospital. TAJ. 2008;21:58–62. Sharmin LS, Haque MA, Bari MI, Ali MA. Pattern and clinical profile of congenital heart disease in a teaching hospital. TAJ. 2008;21:58–62.
14.
go back to reference Vashishta VM, Kalra A, Kalra K, Jain VK. Prevalence of congenital heart disease. Indian Pediatr. 1993;30:1337–40. Vashishta VM, Kalra A, Kalra K, Jain VK. Prevalence of congenital heart disease. Indian Pediatr. 1993;30:1337–40.
15.
16.
go back to reference Bernstein D. Atrial septal defect. In: Kliegman RM, Stanton BMD, St. Geme J, Schor N, Behrman RE, eds. Nelson textbook of pediatrics. 19th ed. Philadelphia: Elsevier; 2011.pp.1551. Bernstein D. Atrial septal defect. In: Kliegman RM, Stanton BMD, St. Geme J, Schor N, Behrman RE, eds. Nelson textbook of pediatrics. 19th ed. Philadelphia: Elsevier; 2011.pp.1551.
17.
go back to reference Jacobs EGJ, Leung MP, Kartberg J. Distribution of symptomatic congenital heart disease in Hong Kong. Pediatr Cardiol. 2005;21:148–57.CrossRef Jacobs EGJ, Leung MP, Kartberg J. Distribution of symptomatic congenital heart disease in Hong Kong. Pediatr Cardiol. 2005;21:148–57.CrossRef
18.
go back to reference Calcagini G, Digillio MC, Sarkozy A, Dallapiccola B, Marino B. Familial recurrence of congenital heart disease:an overview and review of literatues. Eur J Pediatr. 2007;166:111–6.CrossRef Calcagini G, Digillio MC, Sarkozy A, Dallapiccola B, Marino B. Familial recurrence of congenital heart disease:an overview and review of literatues. Eur J Pediatr. 2007;166:111–6.CrossRef
19.
go back to reference Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye .Recurrence of congenital heart defects in families. 2009; 120:295–301. Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye .Recurrence of congenital heart defects in families. 2009; 120:295–301.
21.
go back to reference Kabra S. Antenatal diagnosis of fetal heart disease. Ultrasound Obstet Gynecol. 2009;34:128.CrossRef Kabra S. Antenatal diagnosis of fetal heart disease. Ultrasound Obstet Gynecol. 2009;34:128.CrossRef
22.
go back to reference Salem SA, Osama A, El-Feky. Epidemiological study of congenital heart diseases among children attending outpatient clinics of Benha University Hospital. Egypt J Com Med. 2011;28:69–87. Salem SA, Osama A, El-Feky. Epidemiological study of congenital heart diseases among children attending outpatient clinics of Benha University Hospital. Egypt J Com Med. 2011;28:69–87.
23.
go back to reference Khalil A, Agarwal R, Thirupuram S, Arora R. Incidence of congenital heart disease among hospital live births in India. Indian Pediatr. 1994;31:519–27.PubMed Khalil A, Agarwal R, Thirupuram S, Arora R. Incidence of congenital heart disease among hospital live births in India. Indian Pediatr. 1994;31:519–27.PubMed
24.
go back to reference Gowda Sr, Gawde HM, Hyderi A, Savitha MR, Krishnamurthy B, et al. Chromosomal anomalies and congenital heart disease in Mysore, South India. Int J Hum Genet. 2010;10:131–9. Gowda Sr, Gawde HM, Hyderi A, Savitha MR, Krishnamurthy B, et al. Chromosomal anomalies and congenital heart disease in Mysore, South India. Int J Hum Genet. 2010;10:131–9.
25.
go back to reference Nikyar B, Sedehi M, Mirfazeli A, Qorbani M, Golalipour MJ. Prevalence and pattern of congenital heart disease among neonates in Gorgan, Northern Iran(2007–2008). Iran J Pediatr. 2011;21:307–12.PubMed Nikyar B, Sedehi M, Mirfazeli A, Qorbani M, Golalipour MJ. Prevalence and pattern of congenital heart disease among neonates in Gorgan, Northern Iran(2007–2008). Iran J Pediatr. 2011;21:307–12.PubMed
26.
go back to reference Sadoh WE. Natural history of ventricular septal defects in Nigerian children. SAJCH. 2010;4:16–9. Sadoh WE. Natural history of ventricular septal defects in Nigerian children. SAJCH. 2010;4:16–9.
27.
go back to reference Ruangritnamchai C, Khowsathit P, Pongpanich B. Spontaneous closure of small ventricular septal defect first 6 mo of life. J Med Assoc Thail. 1993;76:63–71. Ruangritnamchai C, Khowsathit P, Pongpanich B. Spontaneous closure of small ventricular septal defect first 6 mo of life. J Med Assoc Thail. 1993;76:63–71.
28.
go back to reference Radzik D, Davignon A, van Doesburg N, Fournier A, Marchand T, Ducharme G. Predictive factors for spontaneous closure of atrial septal defects diagnosed in the first 3 mo of life. J Am Coll Cardiol. 1993;22:851–3.PubMedCrossRef Radzik D, Davignon A, van Doesburg N, Fournier A, Marchand T, Ducharme G. Predictive factors for spontaneous closure of atrial septal defects diagnosed in the first 3 mo of life. J Am Coll Cardiol. 1993;22:851–3.PubMedCrossRef
29.
go back to reference Brassard M, Fouron JC, van Doesburg NH, Mercier LA, De Guise P. Outcome of children with atrial septal defect considered too small for surgical closure. Am J Cardiol. 1999;83:1552–5.PubMedCrossRef Brassard M, Fouron JC, van Doesburg NH, Mercier LA, De Guise P. Outcome of children with atrial septal defect considered too small for surgical closure. Am J Cardiol. 1999;83:1552–5.PubMedCrossRef
30.
go back to reference Helgason H, Jonsdottir G. Spontaneous closure of atrial septal defects. Pediatr Cardiol. 1999;20:195–9.PubMedCrossRef Helgason H, Jonsdottir G. Spontaneous closure of atrial septal defects. Pediatr Cardiol. 1999;20:195–9.PubMedCrossRef
31.
go back to reference McMahon CJ, Feltes TF, Fraley JK, et al. Natural history of growth of secundum atrial septal defects and implications for transcatheter closure. Heart. 2002;87:256–9.PubMedCrossRef McMahon CJ, Feltes TF, Fraley JK, et al. Natural history of growth of secundum atrial septal defects and implications for transcatheter closure. Heart. 2002;87:256–9.PubMedCrossRef
Metadata
Title
Prevalence, Pattern and Outcome of Congenital Heart Disease in Bhabha Atomic Research Centre Hospital, Mumbai
Authors
Sangeeta Priyadarshi Sawant
Alpa Sanjeev Amin
Minakshi Bhat
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
Indian Journal of Pediatrics / Issue 4/2013
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-012-0910-x

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