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Indian Journal of Pediatrics
Published in: Indian Journal of Pediatrics 1/2012

01-01-2012 | Pediatric Radiology

Tuberous Sclerosis Complex: Imaging Findings

Authors: Pankaj Gupta, Amar Mukund, Chandrashekhara S.H., Arun Kumar Gupta

Published in: Indian Journal of Pediatrics | Issue 1/2012

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Excerpt

Tuberous Sclerosis Complex (TSC) is an autosomal dominant disorder with a reported incidence of around 8–9 per 100,000 [1]. It causes significant morbidity and early mortality. Although TSC is classically described as a triad of epilepsy, mental retardation and adenoma sebaceum, epilepsy occurs in 60% and learning disability in 40% of the patients. Thus, imaging plays an important role in diagnosing the disease in patients in whom there is a clinical suspicion and can sometimes raise the suspicion of the disease based on the typical imaging findings. …
Literature
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Wee SA, Fangman B. Tuberous sclerosis. Dermatol Online J. 2007;13:22.PubMed
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Korol UB, Schoor R, Nanda V, Almas K, Phelan JA. Gingival enlargement as a manifestation of tuberous sclerosis: case report and periodontal management. J Periodontol. 2008;79:759–63.PubMedCrossRef
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Van Tassel P, Cure JK, Holden KR. Cystlike white matter lesions in tuberous sclerosis. AJNR Am J Neuroradiol. 1997;18:1367–73.PubMed
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Umeoka S, Koyama T, Miki Y, Akai M, Tsutsui K, Togashi K. Pictorial review of tuberous sclerosis in various organs. Radiographics. 2008;28:e32.PubMedCrossRef
Metadata
Title
Tuberous Sclerosis Complex: Imaging Findings
Authors
Pankaj Gupta
Amar Mukund
Chandrashekhara S.H.
Arun Kumar Gupta
Publication date
01-01-2012
Publisher
Springer-Verlag
Published in
Indian Journal of Pediatrics / Issue 1/2012
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-011-0453-6

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