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Published in: Indian Journal of Pediatrics 4/2011

01-04-2011 | Clinical Brief

Spectrum of Kawasaki Disease

Authors: Megha Consul, Smita Mishra, Arvind Taneja

Published in: Indian Journal of Pediatrics | Issue 4/2011

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Abstract

The authors report 22 patients of Kawasaki disease, diagnosed and treated over a period of 3 years at a tertiary care centre in New Delhi. Ten cases fullfiled the criteria of a “classical” case while 12 cases were “incomplete” cases. Echocardiography was performed in all cases and coronary artery involvement was found in 8 (36%) cases. All cases received high dose Intravenous Immunoglobulins (IVIG) as standard therapy. In two cases, a repeat dose of IVIG was required for defervescence to occur. All cases recovered after therapy. Those with coronary artery involvement were planned for a 2 years follow up from the time of diagnosis.
Literature
1.
go back to reference Kawasaki T, Kosaki F. Febrile oculo-oro-cutaneo-acro-desquamatous ndrome with or without acute non-suppurative cervical lymphadenitis in infancy and childhood: clinical observations of 50 cases. Arerugi. 1967;16:178–222.PubMed Kawasaki T, Kosaki F. Febrile oculo-oro-cutaneo-acro-desquamatous ndrome with or without acute non-suppurative cervical lymphadenitis in infancy and childhood: clinical observations of 50 cases. Arerugi. 1967;16:178–222.PubMed
2.
go back to reference Kawasaki T, Kosaki F, Okawa S, et al. A new infantile acute febrile mucocutaneous lymph syndrome (MLNS) prevailing in Japan. Pediatrics. 1974;54:271–6.PubMed Kawasaki T, Kosaki F, Okawa S, et al. A new infantile acute febrile mucocutaneous lymph syndrome (MLNS) prevailing in Japan. Pediatrics. 1974;54:271–6.PubMed
3.
go back to reference Taneja A, Saxena U. Mucocutaneous lymph node syndrome. Indian Pediatr. 1977;14:927–31.PubMed Taneja A, Saxena U. Mucocutaneous lymph node syndrome. Indian Pediatr. 1977;14:927–31.PubMed
4.
go back to reference Cimaz R, Sundel R. Atypical and incomplete Kawasaki disease, best practice & research clinical rheumatology. Pediatr Rheumatol. 2009;23:689–97. Cimaz R, Sundel R. Atypical and incomplete Kawasaki disease, best practice & research clinical rheumatology. Pediatr Rheumatol. 2009;23:689–97.
5.
go back to reference Rowley AH, Duffy CE, Shulman ST. Prevention of giant aneurysms in Kawasaki Disease by intravenous gammaglobulin therapy. J Pediatr. 1988;113:290–4.PubMedCrossRef Rowley AH, Duffy CE, Shulman ST. Prevention of giant aneurysms in Kawasaki Disease by intravenous gammaglobulin therapy. J Pediatr. 1988;113:290–4.PubMedCrossRef
6.
go back to reference Khubchandani R. Kawasaki disease–call for a national registry for India. Indian Pediatr. 2010;47:200.PubMed Khubchandani R. Kawasaki disease–call for a national registry for India. Indian Pediatr. 2010;47:200.PubMed
7.
go back to reference Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation. 2004;110:2747–71.PubMedCrossRef Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Circulation. 2004;110:2747–71.PubMedCrossRef
8.
go back to reference de Zorzi A, Colan SD, Gauvreau K, Baker AL, Sundel RP, Newburger JW. Coronary artery dimensions may be misclassified as normal in Kawasaki Disease. J Pediatr. 1998;133:254–8.PubMedCrossRef de Zorzi A, Colan SD, Gauvreau K, Baker AL, Sundel RP, Newburger JW. Coronary artery dimensions may be misclassified as normal in Kawasaki Disease. J Pediatr. 1998;133:254–8.PubMedCrossRef
9.
go back to reference Kurotobi S, Nagai T, Kawakami N, Sano T. Coronary diameter in normal infants, children and patients with Kawasaki Disease. Pediatr Int. 2002;44:1–4.PubMedCrossRef Kurotobi S, Nagai T, Kawakami N, Sano T. Coronary diameter in normal infants, children and patients with Kawasaki Disease. Pediatr Int. 2002;44:1–4.PubMedCrossRef
10.
go back to reference Durongpisitkul K, Gururaj VJ, Park JM, Martin CF. The prevention of coronary artery aneurysm in Kawasaki Disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics. 1995;96:1057–61.PubMed Durongpisitkul K, Gururaj VJ, Park JM, Martin CF. The prevention of coronary artery aneurysm in Kawasaki Disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment. Pediatrics. 1995;96:1057–61.PubMed
Metadata
Title
Spectrum of Kawasaki Disease
Authors
Megha Consul
Smita Mishra
Arvind Taneja
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
Indian Journal of Pediatrics / Issue 4/2011
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-010-0356-y

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