Published in:
Open Access
01-12-2016 | Clinical Guides in Oncology
SEOM Clinical Guideline for gastrointestinal sarcomas (GIST) (2016)
Authors:
A. Poveda, V. Martinez, C. Serrano, I. Sevilla, M. J. Lecumberri, R. D. de Beveridge, A. Estival, D. Vicente, J. Rubió, J. Martin-Broto
Published in:
Clinical and Translational Oncology
|
Issue 12/2016
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Abstract
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the digestive tract, and this disease has served as a paradigmatic model for successful rational development of targeted therapies. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. The Spanish Society of Medical Oncology (SEOM) guidelines provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers.