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Clinical and Translational Oncology
Published in: Clinical and Translational Oncology 5/2016

01-05-2016 | Brief Research Article

Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma

Authors: M. P. Crowley, S. B. O’Neill, B. Kevane, D. C. O’Neill, J. A. Eustace, M. R. Cahill, B. Bird, M. M. Maher, K. O’Regan, D. O’Shea

Published in: Clinical and Translational Oncology | Issue 5/2016

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Abstract

Purpose

Survival rates among patients with lymphoma continue to improve. Strategies aimed at reducing potential treatment-related toxicity are increasingly prioritized. While radiological procedures play an important role, ionizing radiation exposure has been linked to an increased risk of malignancy, particularly among individuals whose cumulative radiation exposure exceeds a specific threshold (75 millisieverts).

Methods

Within this retrospective study, the cumulative radiation exposure dose was quantified for 486 consecutive patients with lymphoma.

Results

The median estimated total cumulative effective dose (CED) of ionizing radiation per subject was 69 mSv (42–118). However, younger patients (under 40 years) had a median CED of 89 mSv (55–124).

Conclusion

This study highlights the considerable radiation exposure occurring among patients with lymphoma as a result of diagnostic imaging. To limit the risk of secondary carcinogenesis, consideration should be given to monitoring cumulative radiation exposure in individual patients as well as considering imaging modalities, which do not impart an ionizing radiation dose.
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Metadata
Title
Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma
Authors
M. P. Crowley
S. B. O’Neill
B. Kevane
D. C. O’Neill
J. A. Eustace
M. R. Cahill
B. Bird
M. M. Maher
K. O’Regan
D. O’Shea
Publication date
01-05-2016
Publisher
Springer Milan
Published in
Clinical and Translational Oncology / Issue 5/2016
Print ISSN: 1699-048X
Electronic ISSN: 1699-3055
DOI
https://doi.org/10.1007/s12094-015-1394-8

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