Top

Indian Journal of Otolaryngology and Head & Neck Surgery

Published in:

12-09-2019 | Original Article

Demography and Pattern of Tobacco Usage in Carcinoma of Upper Aerodigestive Tract

Authors: Sachin Gandhi, K. C. Arun, Rashmi Rahul Bagul, Anuj Shah, Supreetha Shenoy

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 2/2022

Abstract

Upper aerodigestive tract (UADT) malignancies account for significant proportion of all malignancies. The aim of the study is to know the demography and patterns of tobacco consumption and the proportion of non-tobacco consumers in patients with UADT carcinoma. Patient diagnosed with primary UADT carcinoma visiting outpatient department in a tertiary centre from February 2009 to May 2011 were included in the study. 150 patients were documented with UADT carcinoma and analysed. Among these 133 were males and 17 were female. 40% of them had smoking, 25% had smokeless tobacco, 13% had both smoking and smokeless tobacco and 22% hadn’t had any form of tobacco. Carcinoma larynx is the most common site and glottis is the commonest subsite. Most individuals who developed UADT carcinoma have used tobacco in some form. The high proportion of UADT carcinoma in non-tobacco consumer is alarming.

Muir C, Weiland L (1995) Upper aerodigestive tract cancers. Cancer 75:147–153CrossRefPubMed

WHO (2004) Monographs on the evaluation of carcinogenic risks to humans. In: Tobacco smoke and involuntary smoking, vol. 82. International Agency for research on cancer, WHO, Lyon

WHO/Cancer. WHO. Available from: http://www.who.int/mediacentre/facesheets/fs297/en

Vineis P, Alavanja M, Buffler P, Fontham E, Franceschi S, Gao YT et al (2004) Tobacco and cancer: recent epidemiological evidencce. J Natl Cancer Inst 96:99–106CrossRefPubMed

Brunnemann KD, Hoffmann D (1992) Chemical composition of smokeless tobacco products. In: Smokeless tobacco of health. An international perspective. National cancer institute, Bethesda

West R, Marques CR, Marques Filho MF, Marques AB, Di Pietro G, Rios-santos F (2014) Association of the GSTT1 polymorphism in upper aerodigestive tract cancer with tobacco smoking. Genet Mol Res 13:528–537CrossRef

Hodge KM, Flynn MB, Drury T (1985) Squamous cell carcinoma of the upper aerodigestive tract in nonusers of tobacco. Cancer 55:1232–1235CrossRefPubMed

Chaturvedi AK, Engels EA, Anderson WF, Gillison ML (2008) Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. J Clin Oncol 26:612–619. https://doi.org/10.1200/JCO.2007.14.1713CrossRefPubMed

Pytynia KB, Dahlstrom KR, Sturgis EM (2014) Epidemiology of HPV-associated oropharyngeal cancer. Oral Oncol 50:380–386. https://doi.org/10.1016/j.oraloncology.2013.12.019CrossRefPubMedPubMedCentral

10.

Platek AJ, Cannioto RA, Etter JL, Kim J, Joseph JM et al (2017) The association of lifetime physical inactivity with head and neck cancer: a hospital-based case-control analysis. Eur Arch Otorhinolaryngol 274(10):3773–3780CrossRefPubMedPubMedCentral

11.

Shu CC, Mazda JE, Cristina B, Renato T et al (2012) Diet and the risk of head and neck cancer: a pooled analysis in the inhance consortium. Cancer Causes Control 23(1):69–88CrossRef

12.

Cadoni G, Bocia S, Peterelli L, Giannantoni PD, Arzani D et al (2012) A review of genetic epidemiology of head and neck cancer related to polymorphisms in metabolic genes, cell cycle control and alcohol metabolism. Acta Otorhinolaryngol Ital 32(1):1–11PubMedPubMedCentral

13.

Wynder EL, Covey LS (1976) Environment factors in cancer of the larynx. Cancer 38:1591–1601CrossRefPubMed

14.

Wiseman SM, Loree TR (2003) Squamous cell carcinoma of the head and neck in non-smokers and non-drinkers: an analysis of clinicopathologic characteristics and treatment outcomes. Ann Surg Oncol 10:551–557CrossRefPubMed

15.

Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML, Daniel RW, Viglione M, Symer DE et al (2000) Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 92:709–720. https://doi.org/10.1093/jnci/92.9.709CrossRefPubMed

16.

Junor E, Kerr G, Oniscu A, Campbell S, Kouzeli I, Gourley C et al (2012) Benefit of chemotherapy as part of treatment for HPV DNA-positive but P16-negative squamous cell carcinoma of the oropharynx. Br J Cancer 106:358–365. https://doi.org/10.1038/bjc.2011.542CrossRefPubMed

17.

Maryam A, Mohammad SK, Ghasem AS, Marzieh A, Hamed RK (2017) Pesticide exposure and head and neck cancers: a case-control study in an agricultural region. Iran J Otorhinolaryngol 29(94):275–285

18.

Koch WM, Lango M (1999) Head and neck cancer in non-smokers: a distinct clinical and molecular entity. Laryngoscope 109:1544–1550CrossRefPubMed

19.

Spitz MR, Fueger JJ, Goepfert H et al (1988) Squamous cell carcinoma of the upper aerodigestive tract cancer. Cancer 61:203–208CrossRefPubMed

20.

Wynder EL, Stellman SD (1979) Impact of long term filter cigarette usage on lung and larynx cancer risk: a case control study. J Natl Cancer Inst 62:471–477CrossRefPubMed

21.

Burch JD, Howe GR (1981) Tobacco, alcohol, asbestos and nickel in the etiology of cancer of the larynx: a case control study. J Natl Cancer Inst 67:1219–1224PubMed

Title: Demography and Pattern of Tobacco Usage in Carcinoma of Upper Aerodigestive Tract
Authors: Sachin Gandhi
K. C. Arun
Rashmi Rahul Bagul
Anuj Shah
Supreetha Shenoy
Publication date: 12-09-2019
Publisher: Springer India
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 2/2022
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-019-01733-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Demography and Pattern of Tobacco Usage in Carcinoma of Upper Aerodigestive Tract

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Special Issue 2/2022

Human Papillomavirus-Associated Oral Squamous Cell Carcinoma Among Adults Living in South-Central Asia: A Systematic Review

Subjective and Objective Outcome Assessment in Patients with Sinonasal Disease After Microdebrider Assisted Endoscopic Sinus Surgery

An Otorhinolaryngologists Perspective on Using Face Masks by Health Care Professionals Based on an Online Survey

Are Low Serum Vitamin D Levels a Risk Factor for Advent of COVID-19 Associated Rhinocerebral Mucormycosis: A Preliminary Case Control Study

The Relationship Between Temporal Bone Pneumatization Pattern and Sinus Mucosal Thickness Grading on Computed Tomography Scans of Paranasal Sinuses

Laryngeal Trauma Managed with Titanium Mesh Fixation: A Rare Case Report