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Indian Journal of Otolaryngology and Head & Neck Surgery

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01-10-2019 | Foreign Body Aspiration | Original Article

A Comparative Study on Aspiration Cytology and Histopathology in Diagnosis of Thyroid Nodule and Its Correlation

Authors: Pijush Kumar Roy, Shyama Bandyopadhyay, Arya Brata Dubey, Arunabha Sengupta

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 1/2019

Abstract

Introduction

Fine Needle Aspiration Cytology (FNAC) is an initial diagnostic test that has been found to be simple and cost effective but it is associated with pitfalls due to difference in correlations between FNAC and Histopathological Examination (HPE).

Methods

A study was undertaken with a total of 112 patientspresenting with thyroid nodule who underwent thyroid surgeries. Preoperative FNAC and postoperative HPE were evaluated to calculate sensitivity, specificity, positive and negative predictive value and accuracy.

Results

In our study we found sensitivity to be 81.48%, specificity 95.29%, positive predictive value 84.61%, Negative predictive value 94.18% and accuracy to be 91.16%.

Conclusion

Thus we can conclude that FNAC is a simple, safe and cost-effective diagnostic modality in the investigation of Thyroid nodule with high specificity and accuracy.

American Thyroid Association (2015) American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer (Recommendation 7)

National Comprehensive Cancer Network (www.nccn.org)

Gritzmann N, Koischwitz D, Rettenbacher T (2000) Sonography of the thyroid and parathyroid glands. Radio Clin North Am 38(5):1131–1145CrossRef

Chow LS, Gharib H, Goellener JR, Van Heerden JA (2001) Non-diagnostic thyroid fine needle aspiration cytology: management dilemmas. Thyroid 11:1147–1157CrossRef

Mohan H (2005) Textbook of pathology, 5th edn. Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, pp 934–939CrossRef

Burch HB, Burman KD, Reed HI, Buckner L, Raber T, Ownbey JL (1996) Fine needle aspiration of thyroid nodules. Determinants of insufficiency rate and malignancy yield at thyroidectomy. Acta Cytol 40:1176–1183CrossRef

Gharib H, Goellner JR (1993) Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med 118:282–289CrossRef

Franklyn JA, Sheppard MC (1987) Aspiration cytology of thyroid. BMJ 295:510–511CrossRef

Gupta M, Gupta S, Gupta VB (2010) Correlation of fine needle aspiration cytology with histopathology in the diagnosis of solitary thyroid nodule. J Thyroid Res Article ID 379051, 5 pages. https://doi.org/10.4061/2010/379051 CrossRef

10.

Islam MS, Siddiquee BH, Akhtar N, Salam KS, Aktaruzzaman M (2010) Comparative study of FNAC and histopathology in the diagnosis of thyroid swelling. Bangladesh J Otorhinolaryngol 16(1):35–43CrossRef

11.

Sreeramulu PN, Venkatachalapathy TS, Prathima S, Kishore K (2012) A prospective study of clinical, sonological and pathological evaluation of thyroid nodule. J Biosci Technol 3(1):474–478

12.

Kamal M, Dilip GA, Hemant RK (2002) Comparative study of fine needle aspiration and fine needle capillary sampling of thyroid lesions. ActaCytol 46(1):30–34

13.

Afroze N, Kayani N, Hasan SH (2002) Role of fine needle aspiration cytology in the diagnosis of palpable thyroid lesions. Indian J PatholMicrobiol 45(3):241–246

14.

Safirullah, Mumtaz N, Akbar K (2004) The role of fine needle aspiration cytology in the diagnosis of thyroid swellings. JPMI 18(2):196–201

15.

Rizvi SA, Husain M, Khan S, Mohsin M (2005) A comparative study of fine needle aspiration cytology versus non-aspiration technique in thyroid lesions. Surgeon 3(4):273–276CrossRef

16.

Sengupta A, Pal R, Kar S, Zaman FA, Sengupta S, Pal S (2011) Fine needle aspiration cytology as the primary diagnostic tool in thyroid enlargement. J Nat Sci Biol Med 2(1):113–118CrossRef

17.

Agarwal S (1995) Diagnostic accuracy and role of fine needle aspiration cytology in management of thyroid nodules. J SurgOncol. 58(3):168–172

18.

Dorairajan N, Jayashree N (1996) Solitary nodule of thethyroid and the role of fine needle aspiration cytology indiagnosis. J Indian Med Assoc 94(2):50–52PubMed

19.

Kessler A, Gavriel H, Zahav S et al (2005) Accuracy andconsistency of fine-needle aspiration biopsy in the diagnosis and management of solitary thyroid nodules. Israel Med Assoc J 7(6):371–373

20.

Ravetto C, Colombo L, Dottorini ME (2000) Usefulness offine-needlein the diagnosis of thyroid carcinoma: a retrospectivestudy in 37,895 patients. Cancer 90(6):357–363CrossRef

Title: A Comparative Study on Aspiration Cytology and Histopathology in Diagnosis of Thyroid Nodule and Its Correlation
Authors: Pijush Kumar Roy
Shyama Bandyopadhyay
Arya Brata Dubey
Arunabha Sengupta
Publication date: 01-10-2019
Publisher: Springer India
Keywords: Foreign Body Aspiration
Foreign Body Aspiration
Aspiration
Goiter
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 1/2019
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-019-01681-3

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A Comparative Study on Aspiration Cytology and Histopathology in Diagnosis of Thyroid Nodule and Its Correlation

Abstract

Introduction

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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