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Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 3/2017

01-09-2017 | Clinical Report

Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma: Case Series

Authors: Chian Ling Tang, Ramesh Kumar, Charng Jeng Toh, Shahizon Azura, Geok Chin Tan, Balwant Singh Gendeh

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 3/2017

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Abstract

Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.
Literature
1.
go back to reference Bailet JW, Mark RJ, Abemayor E et al (1992) Nasopharyngeal carcinoma: treatment results with primary radiation therapy. Laryngoscope 102(9):965–972CrossRefPubMed Bailet JW, Mark RJ, Abemayor E et al (1992) Nasopharyngeal carcinoma: treatment results with primary radiation therapy. Laryngoscope 102(9):965–972CrossRefPubMed
2.
go back to reference Chrcanovic BR, Reher P, Sousa AA, Harris M (2010) Osteoradionecrosis of the jaws—a current overview-part 1: physiopathology and risk and predisposing factors. Oral Maxillofac Surg 14(1):3–16CrossRefPubMed Chrcanovic BR, Reher P, Sousa AA, Harris M (2010) Osteoradionecrosis of the jaws—a current overview-part 1: physiopathology and risk and predisposing factors. Oral Maxillofac Surg 14(1):3–16CrossRefPubMed
3.
go back to reference Ozyar E, Selek U, Laskar S et al (2006) Treatment results of 165 pediatric patients with non-metastatic nasopharyngeal carcinoma: a rare cancer network study. Radiother Oncol 81(1):39–46CrossRefPubMed Ozyar E, Selek U, Laskar S et al (2006) Treatment results of 165 pediatric patients with non-metastatic nasopharyngeal carcinoma: a rare cancer network study. Radiother Oncol 81(1):39–46CrossRefPubMed
4.
go back to reference Baki MM, Gendeh BS (2006) Acquired posterior choanal atresia: post-radiotherapy. Med J Malays 61(1):94–96 Baki MM, Gendeh BS (2006) Acquired posterior choanal atresia: post-radiotherapy. Med J Malays 61(1):94–96
5.
go back to reference Lee AW, Foo W, Chappell R et al (1998) Effect of time, dose, and fractionation on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 40(1):35–42CrossRefPubMed Lee AW, Foo W, Chappell R et al (1998) Effect of time, dose, and fractionation on temporal lobe necrosis following radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 40(1):35–42CrossRefPubMed
6.
go back to reference Lee AW, Ng SH, Ho JHC et al (1988) Clinical diagnosis of late temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma. Cancer 61(8):1535–1542CrossRefPubMed Lee AW, Ng SH, Ho JHC et al (1988) Clinical diagnosis of late temporal lobe necrosis following radiation therapy for nasopharyngeal carcinoma. Cancer 61(8):1535–1542CrossRefPubMed
7.
go back to reference Leuthardt EC, Wippold FJ 2nd, Oswood MC, Rich KM (2002) Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses. Surg Neurol 58(6):395–402 (discussion 402) CrossRefPubMed Leuthardt EC, Wippold FJ 2nd, Oswood MC, Rich KM (2002) Diffusion-weighted MR imaging in the preoperative assessment of brain abscesses. Surg Neurol 58(6):395–402 (discussion 402) CrossRefPubMed
8.
go back to reference Muccio CF, Esposito G, Bartolini A, Cerase A (2008) Cerebral abscesses and necrotic cerebral tumours: differential diagnosis by perfusion weighted magnetic resonance imaging. Radiol Med 113(5):747–757CrossRefPubMed Muccio CF, Esposito G, Bartolini A, Cerase A (2008) Cerebral abscesses and necrotic cerebral tumours: differential diagnosis by perfusion weighted magnetic resonance imaging. Radiol Med 113(5):747–757CrossRefPubMed
9.
go back to reference Asao C, Korogi Y, Kitajima M et al (2005) Diffusion-weighted imaging of radiation induced brain injury for differentiation from tumor recurrence. AJNR Am J Neuroradiol 26(6):1455–1460PubMed Asao C, Korogi Y, Kitajima M et al (2005) Diffusion-weighted imaging of radiation induced brain injury for differentiation from tumor recurrence. AJNR Am J Neuroradiol 26(6):1455–1460PubMed
10.
go back to reference Hary GB, Mainous EG (1976) The treatment of radiation necrosis with hyperbaric oxygen (OHP). Cancer 37:2580–2585CrossRef Hary GB, Mainous EG (1976) The treatment of radiation necrosis with hyperbaric oxygen (OHP). Cancer 37:2580–2585CrossRef
11.
go back to reference Cheung MC, Chan AS, Law SC, Chan JH, Tse VK (2000) Cognitive function of patients with nasopharyngeal carcinoma with and without temporal lobe radionecrosis. Arch Neurol 57:1347–1352PubMed Cheung MC, Chan AS, Law SC, Chan JH, Tse VK (2000) Cognitive function of patients with nasopharyngeal carcinoma with and without temporal lobe radionecrosis. Arch Neurol 57:1347–1352PubMed
Metadata
Title
Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma: Case Series
Authors
Chian Ling Tang
Ramesh Kumar
Charng Jeng Toh
Shahizon Azura
Geok Chin Tan
Balwant Singh Gendeh
Publication date
01-09-2017
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 3/2017
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-015-0909-5

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