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Indian Journal of Otolaryngology and Head & Neck Surgery

Published in:

01-01-2013 | Original Article

Impact of Clinical and Histo-Pathological Prognostic Factors on T1-2N0-1 Oral Tongue Carcinoma

Authors: Pichit Sittitrai, Chonticha Srivanitchapoom, Pongsak Mahanupab, Thienchai Pattarasakulchai, Rak Tananuvat, Warat Unejanum

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Issue 1/2013

Abstract

To determine predictive factors which affect local and regional recurrence of T1-2N0-1M0 oral tongue carcinoma (OTC). Records of 42 patients with T1-2N0-1 M0 OTC were reviewed. The clinical characteristics, histo-pathological data, disease recurrence and survival rate were analyzed. Descriptive statistics and Kaplan–Meier survival analysis were used. The median follow up was 38 months. The 2-year overall survival and disease-free survival rates were 85.7 and 55.6 % respectively. At the 2 year analysis, there were surgical margin <5 mm (p value = 0.01), tumor thickness >7 mm (p value = 0.03), perivascular and perilymphatic invasion (p value = 0.01) affected on local recurrence and perivascular and perilymphatic invasion were also predictors for regional recurrence (p value = 0.04). The surgical margin status, tumor thickness, perivascular and perilymphatic invasion represented significant predictive factors for local recurrent OTC. Postoperative adjuvant therapy should be considered in these groups.

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Title: Impact of Clinical and Histo-Pathological Prognostic Factors on T1-2N0-1 Oral Tongue Carcinoma
Authors: Pichit Sittitrai
Chonticha Srivanitchapoom
Pongsak Mahanupab
Thienchai Pattarasakulchai
Rak Tananuvat
Warat Unejanum
Publication date: 01-01-2013
Publisher: Springer-Verlag
Published in: Indian Journal of Otolaryngology and Head & Neck Surgery / Issue 1/2013
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI: https://doi.org/10.1007/s12070-012-0605-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of Clinical and Histo-Pathological Prognostic Factors on T1-2N0-1 Oral Tongue Carcinoma

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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