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Published in: Indian Journal of Thoracic and Cardiovascular Surgery 3/2021

01-05-2021 | Myocardial Infarction | Simply Statistics

Survival analysis—part 3: intermediate events and the importance of competing risks

Authors: Salil Vasudeo Deo, Vaishali Deo, Varun Sundaram

Published in: Indian Journal of Thoracic and Cardiovascular Surgery | Issue 3/2021

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Abstract

Learning objectives:
1.
Understand what events can be labelled as intermediate events in survival analysis.
 
2.
Understand why the Kaplan and Meier method cannot be used in the presence of competing events.
 
3.
Regression analysis in the presence of competing events.
 
Literature
1.
go back to reference David W, Hosmer SL, May S. Applied survival analysis: regression modeling of time-to-event data. New York: John Wiley & Sons, Inc; 2008. David W, Hosmer SL, May S. Applied survival analysis: regression modeling of time-to-event data. New York: John Wiley & Sons, Inc; 2008.
2.
go back to reference Austin PC, Lee DS, Fine JP. Introduction to the analysis of survival data in the presence of competing risks. Circulation. 2016;133:601–9. Austin PC, Lee DS, Fine JP. Introduction to the analysis of survival data in the presence of competing risks. Circulation. 2016;133:601–9.
3.
go back to reference Verduijn M, Grootendorst DC, Dekker FW, Jager KJ, le Cessie S. The analysis of competing events like cause-specific mortality--beware of the Kaplan-Meier method. Nephrol Dial Transplant. 2011;26:56–61. Verduijn M, Grootendorst DC, Dekker FW, Jager KJ, le Cessie S. The analysis of competing events like cause-specific mortality--beware of the Kaplan-Meier method. Nephrol Dial Transplant. 2011;26:56–61.
4.
go back to reference Lau B, Cole SR, Gange SJ. Competing risk regression models for epidemiologic data. Am J Epidemiol. 2009;170:244–56. Lau B, Cole SR, Gange SJ. Competing risk regression models for epidemiologic data. Am J Epidemiol. 2009;170:244–56.
5.
go back to reference Austin PC, Fine JP. Accounting for competing risks in randomized controlled trials: a review and recommendations for improvement. Stat Med. 2017;36:1203–9. Austin PC, Fine JP. Accounting for competing risks in randomized controlled trials: a review and recommendations for improvement. Stat Med. 2017;36:1203–9.
Metadata
Title
Survival analysis—part 3: intermediate events and the importance of competing risks
Authors
Salil Vasudeo Deo
Vaishali Deo
Varun Sundaram
Publication date
01-05-2021
Publisher
Springer Singapore
Published in
Indian Journal of Thoracic and Cardiovascular Surgery / Issue 3/2021
Print ISSN: 0970-9134
Electronic ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-021-01151-y

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