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Neurocritical Care

Published in:

01-10-2012 | Original Article

The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics

Authors: Paul E. Marik, Alisha Young, Steve Sibole, Alex Levitov

Published in: Neurocritical Care | Issue 2/2012

Abstract

Background

Airway pressure release ventilation (APRV) is an alternative approach to the low-tidal volume “open-lung” ventilation strategy. APRV is associated with a higher mean airway pressure than conventional ventilation and has therefore not been evaluated in patients with acute neurological injuries.

Methods

Case report.

Results

We report a patient with severe progressive hypoxemia following a subarachnoid hemorrhage who was converted from pressure-controlled mechanical ventilation to APRV. This change in ventilatory mode was associated with a significant improvement in oxygenation and alveolar ventilation with an associated increase in cerebral blood flow and a negligible increase in intracranial pressure.

Conclusion

APRV may safely be applied to neurocritically ill patients, and that this mode of ventilation may increase cerebral blood flow without increasing intracranial pressure.

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Title: The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics
Authors: Paul E. Marik
Alisha Young
Steve Sibole
Alex Levitov
Publication date: 01-10-2012
Publisher: Humana Press Inc
Published in: Neurocritical Care / Issue 2/2012
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI: https://doi.org/10.1007/s12028-012-9739-4

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

The Effect of APRV Ventilation on ICP and Cerebral Hemodynamics

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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