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Immunologic Research
Published in: Immunologic Research 1-3/2012

01-09-2012 | Singapore Immunology Network

Macrophage polarization and plasticity in health and disease

Authors: Subhra K. Biswas, Manesh Chittezhath, Irina N. Shalova, Jyue-Yuan Lim

Published in: Immunologic Research | Issue 1-3/2012

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Abstract

The role of myelomonocytic cells like monocytes and macrophages as first line of host defense is well established. Recent understanding of these cells using systems biology, transgenesis and in disease models has brought them to a center stage in orchestrating crucial functions during homeostasis and pathogenesis. Thus, understanding the functional diversity of these cells in health and disease as well as the mechanisms that control these events would be crucial for designing strategies for regulating disease and reinstate homeostasis.
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Metadata
Title
Macrophage polarization and plasticity in health and disease
Authors
Subhra K. Biswas
Manesh Chittezhath
Irina N. Shalova
Jyue-Yuan Lim
Publication date
01-09-2012
Publisher
Springer-Verlag
Published in
Immunologic Research / Issue 1-3/2012
Print ISSN: 0257-277X
Electronic ISSN: 1559-0755
DOI
https://doi.org/10.1007/s12026-012-8291-9

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