Skip to main content
Top
Published in: Forensic Science, Medicine and Pathology 4/2009

01-12-2009 | Review

Neuroimaging of abusive head trauma

Authors: Gary L. Hedlund, Lori D. Frasier

Published in: Forensic Science, Medicine and Pathology | Issue 4/2009

Login to get access

Abstract

The diagnostic process for evaluating suspected abusive head trauma in infants and children has evolved with technological advances in neuroimaging. Since Caffey first described a series of children with chronic subdural hematomas and multiple long bone fractures, radiologists have played an important role, along with pediatricians and pathologists, in evaluating abused children. Neuroimaging modalities include ultrasound, CT scans, and MRI technology. Each has distinct clinical applications, as well as practical uses in the clinical diagnostic process of AHT. Importantly, neuroimaging assists in the process of differential diagnosis of other conditions which may mimic AHT. Collaboration between neuroradiologists, clinicians, and pathologists remains critical to making the appropriate diagnosis. Careful history, physical examination, and investigation by legal authorities form the components that result in accurate assessment of any case. This paper reviews pertinent neuroimaging modalities currently utilized in the diagnosis of AHT, describing clinical indications and a collaborative approach to this process.
Literature
1.
go back to reference Frasier LD. Abusive head trauma in infants and young children: a unique contributor to developmental disabilities. Pediatr Clin North Am. 2008;55(6):1269–85. vii.CrossRefPubMed Frasier LD. Abusive head trauma in infants and young children: a unique contributor to developmental disabilities. Pediatr Clin North Am. 2008;55(6):1269–85. vii.CrossRefPubMed
2.
go back to reference Caffey J. Multiple fractures in the long bones of infants suffering from chronic subdural hematoma. Am J Roentgen. 1946;56(1):163–73. Caffey J. Multiple fractures in the long bones of infants suffering from chronic subdural hematoma. Am J Roentgen. 1946;56(1):163–73.
3.
go back to reference Caffey J. The whiplash shaken infant syndrome: manual shaking by the extremities with whiplash-induced intracranial and intraocular bleedings, linked with residual permanent brain damage and mental retardation. Pediatrics. 1974;54(4):396–403.PubMed Caffey J. The whiplash shaken infant syndrome: manual shaking by the extremities with whiplash-induced intracranial and intraocular bleedings, linked with residual permanent brain damage and mental retardation. Pediatrics. 1974;54(4):396–403.PubMed
4.
go back to reference Jenny C, Hymel KP, Ritzen A, Reinert SE, Hay TC. Analysis of missed cases of abusive head trauma. JAMA. 1999;281(7):621–6.CrossRefPubMed Jenny C, Hymel KP, Ritzen A, Reinert SE, Hay TC. Analysis of missed cases of abusive head trauma. JAMA. 1999;281(7):621–6.CrossRefPubMed
5.
go back to reference Vellody K, Freeto JP, Gage SL, Collins N, Gershan WM. Clues that aid in the diagnosis of nonaccidental trauma presenting as an apparent life-threatening event. Clin Pediatr (Phila). 2008;47(9):912–8.CrossRef Vellody K, Freeto JP, Gage SL, Collins N, Gershan WM. Clues that aid in the diagnosis of nonaccidental trauma presenting as an apparent life-threatening event. Clin Pediatr (Phila). 2008;47(9):912–8.CrossRef
6.
go back to reference Waseem M, Pinkert H. Apparent life-threatening event or child abuse? Pediatr Emerg Care. 2006;22(4):245–6.CrossRefPubMed Waseem M, Pinkert H. Apparent life-threatening event or child abuse? Pediatr Emerg Care. 2006;22(4):245–6.CrossRefPubMed
7.
go back to reference Altman RL, Brand DA, Forman S, et al. Abusive head injury as a cause of apparent life-threatening events in infancy. Arch Pediatr Adolesc Med. 2003;157(10):1011–5.CrossRefPubMed Altman RL, Brand DA, Forman S, et al. Abusive head injury as a cause of apparent life-threatening events in infancy. Arch Pediatr Adolesc Med. 2003;157(10):1011–5.CrossRefPubMed
8.
9.
go back to reference Foerster BR, Petrou M, Lin D, et al. Neuroimaging evaluation of non-accidental head trauma with correlation to clinical outcomes: a review of 57 cases. J Pediatr. 2009;154(4):573–7.CrossRefPubMed Foerster BR, Petrou M, Lin D, et al. Neuroimaging evaluation of non-accidental head trauma with correlation to clinical outcomes: a review of 57 cases. J Pediatr. 2009;154(4):573–7.CrossRefPubMed
10.
go back to reference Kemp AM, Rajaram S, Mann M, et al. What neuroimaging should be performed in children in whom inflicted brain injury (iBI) is suspected? A systematic review. Clin Radiol. 2009;64(5):473–83.CrossRefPubMed Kemp AM, Rajaram S, Mann M, et al. What neuroimaging should be performed in children in whom inflicted brain injury (iBI) is suspected? A systematic review. Clin Radiol. 2009;64(5):473–83.CrossRefPubMed
11.
go back to reference Tung GA, Kumar M, Richardson RC, Jenny C, Brown WD. Comparison of accidental and nonaccidental traumatic head injury in children on noncontrast computed tomography. Pediatrics. 2006;118(2):626–33.CrossRefPubMed Tung GA, Kumar M, Richardson RC, Jenny C, Brown WD. Comparison of accidental and nonaccidental traumatic head injury in children on noncontrast computed tomography. Pediatrics. 2006;118(2):626–33.CrossRefPubMed
12.
go back to reference Fujiwara T, Okuyama M, Miyasaka M. Characteristics that distinguish abusive from nonabusive head trauma among young children who underwent head computed tomography in Japan. Pediatrics. 2008;122(4):e841–7.CrossRefPubMed Fujiwara T, Okuyama M, Miyasaka M. Characteristics that distinguish abusive from nonabusive head trauma among young children who underwent head computed tomography in Japan. Pediatrics. 2008;122(4):e841–7.CrossRefPubMed
13.
go back to reference Ashwal S, Holshouser BA, Tong KA. Use of advanced neuroimaging techniques in the evaluation of pediatric traumatic brain injury. Dev Neurosci. 2006;28(4–5):309–26.CrossRefPubMed Ashwal S, Holshouser BA, Tong KA. Use of advanced neuroimaging techniques in the evaluation of pediatric traumatic brain injury. Dev Neurosci. 2006;28(4–5):309–26.CrossRefPubMed
14.
go back to reference Sehgal V, Delproposto Z, Haddar D, et al. Susceptibility-weighted imaging to visualize blood products and improve tumor contrast in the study of brain masses. J Magn Reson Imaging. 2006;24(1):41–51.CrossRefPubMed Sehgal V, Delproposto Z, Haddar D, et al. Susceptibility-weighted imaging to visualize blood products and improve tumor contrast in the study of brain masses. J Magn Reson Imaging. 2006;24(1):41–51.CrossRefPubMed
15.
go back to reference Tong KA, Ashwal S, Holshouser BA, et al. Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology. 2003;227(2):332–9.CrossRefPubMed Tong KA, Ashwal S, Holshouser BA, et al. Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology. 2003;227(2):332–9.CrossRefPubMed
16.
go back to reference Babikian T, Freier MC, Ashwal S, Riggs ML, Burley T, Holshouser BA. MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI. J Magn Reson Imaging. 2006;24(4):801–11.CrossRefPubMed Babikian T, Freier MC, Ashwal S, Riggs ML, Burley T, Holshouser BA. MR spectroscopy: predicting long-term neuropsychological outcome following pediatric TBI. J Magn Reson Imaging. 2006;24(4):801–11.CrossRefPubMed
17.
go back to reference Holshouser BA, Tong KA, Ashwal S, et al. Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury. J Magn Reson Imaging. 2006;24(1):33–40.CrossRefPubMed Holshouser BA, Tong KA, Ashwal S, et al. Prospective longitudinal proton magnetic resonance spectroscopic imaging in adult traumatic brain injury. J Magn Reson Imaging. 2006;24(1):33–40.CrossRefPubMed
18.
go back to reference Bonnier C, Marique P, Van Hout A, Potelle D. Neurodevelopmental outcome after severe traumatic brain injury in very young children: role for subcortical lesions. J Child Neurol. 2007;22(5):519–29.CrossRefPubMed Bonnier C, Marique P, Van Hout A, Potelle D. Neurodevelopmental outcome after severe traumatic brain injury in very young children: role for subcortical lesions. J Child Neurol. 2007;22(5):519–29.CrossRefPubMed
19.
go back to reference Koumellis P, McConachie NS, Jaspan T. Spinal subdural haematomas in children with non-accidental head injury. Arch Dis Child. 2009;94(3):216–9.CrossRefPubMed Koumellis P, McConachie NS, Jaspan T. Spinal subdural haematomas in children with non-accidental head injury. Arch Dis Child. 2009;94(3):216–9.CrossRefPubMed
20.
go back to reference Sato Y, Yuh WT, Smith WL, Alexander RC, Kao SC, Ellerbroek CJ. Head injury in child abuse: evaluation with MR imaging. Radiology. 1989;173(3):653–7.PubMed Sato Y, Yuh WT, Smith WL, Alexander RC, Kao SC, Ellerbroek CJ. Head injury in child abuse: evaluation with MR imaging. Radiology. 1989;173(3):653–7.PubMed
21.
go back to reference Levin AV, Magnusson MR, Rafto SE, Zimmerman RA. Shaken baby syndrome diagnosed by magnetic resonance imaging. Pediatr Emerg Care. 1989;5(3):181–6.CrossRefPubMed Levin AV, Magnusson MR, Rafto SE, Zimmerman RA. Shaken baby syndrome diagnosed by magnetic resonance imaging. Pediatr Emerg Care. 1989;5(3):181–6.CrossRefPubMed
22.
go back to reference Sert A. Cranial ultrasound as a non-invasive diagnostic technique in the diagnosis of subdural haemorrhage. Arch Dis Child. 2007;92(5):468.PubMed Sert A. Cranial ultrasound as a non-invasive diagnostic technique in the diagnosis of subdural haemorrhage. Arch Dis Child. 2007;92(5):468.PubMed
23.
go back to reference Zenger MN, Kabatas S, Zenger S, Cakmakci H. The value of power Doppler ultrasonography in the differential diagnosis of intracranial extraaxial fluid collections. Diagn Interv Radiol. 2007;13(2):61–3.PubMed Zenger MN, Kabatas S, Zenger S, Cakmakci H. The value of power Doppler ultrasonography in the differential diagnosis of intracranial extraaxial fluid collections. Diagn Interv Radiol. 2007;13(2):61–3.PubMed
24.
go back to reference Looney CB, Smith JK, Merck LH, et al. Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors. Radiology. 2007;242(2):535–41.CrossRefPubMed Looney CB, Smith JK, Merck LH, et al. Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors. Radiology. 2007;242(2):535–41.CrossRefPubMed
25.
go back to reference Whitby EH, Griffiths PD, Rutter S, et al. Frequency and natural history of subdural haemorrhages in babies and relation to obstetric factors. Lancet. 2004;363(9412):846–51.CrossRefPubMed Whitby EH, Griffiths PD, Rutter S, et al. Frequency and natural history of subdural haemorrhages in babies and relation to obstetric factors. Lancet. 2004;363(9412):846–51.CrossRefPubMed
26.
go back to reference Towner D, Castro MA, Eby-Wilkens E, Gilbert WM. Effect of mode of delivery in nulliparous women on neonatal intracranial injury. N Engl J Med. 1999;341(23):1709–14.CrossRefPubMed Towner D, Castro MA, Eby-Wilkens E, Gilbert WM. Effect of mode of delivery in nulliparous women on neonatal intracranial injury. N Engl J Med. 1999;341(23):1709–14.CrossRefPubMed
27.
go back to reference Rooks VJ, Eaton JP, Ruess L, Petermann GW, Keck-Wherley J, Pedersen RC. Prevalence and evolution of intracranial hemorrhage in asymptomatic term infants. AJNR Am J Neuroradiol. 2008;29(6):1082–9.CrossRefPubMed Rooks VJ, Eaton JP, Ruess L, Petermann GW, Keck-Wherley J, Pedersen RC. Prevalence and evolution of intracranial hemorrhage in asymptomatic term infants. AJNR Am J Neuroradiol. 2008;29(6):1082–9.CrossRefPubMed
28.
go back to reference Hellbusch LC. Benign extracerebral fluid collections in infancy: clinical presentation and long-term follow-up. J Neurosurg. 2007;107(2 suppl):119–25.PubMed Hellbusch LC. Benign extracerebral fluid collections in infancy: clinical presentation and long-term follow-up. J Neurosurg. 2007;107(2 suppl):119–25.PubMed
29.
go back to reference Aoki N. Extracerebral fluid collections in infancy: role of magnetic resonance imaging in differentiation between subdural effusion and subarachnoid space enlargement. J Neurosurg. 1994;81(1):20–3.CrossRefPubMed Aoki N. Extracerebral fluid collections in infancy: role of magnetic resonance imaging in differentiation between subdural effusion and subarachnoid space enlargement. J Neurosurg. 1994;81(1):20–3.CrossRefPubMed
30.
go back to reference Pittman T. Significance of a subdural hematoma in a child with external hydrocephalus. Pediatr Neurosurg. 2003;39(2):57–9.CrossRefPubMed Pittman T. Significance of a subdural hematoma in a child with external hydrocephalus. Pediatr Neurosurg. 2003;39(2):57–9.CrossRefPubMed
31.
go back to reference Raul JS, Roth S, Ludes B, Willinger R. Influence of the benign enlargement of the subarachnoid space on the bridging veins strain during a shaking event: a finite element study. Int J Legal Med. 2008;122(4):337–40.CrossRefPubMed Raul JS, Roth S, Ludes B, Willinger R. Influence of the benign enlargement of the subarachnoid space on the bridging veins strain during a shaking event: a finite element study. Int J Legal Med. 2008;122(4):337–40.CrossRefPubMed
32.
go back to reference McNeely PD, Atkinson JD, Saigal G, O’Gorman AM, Farmer JP. Subdural hematomas in infants with benign enlargement of the subarachnoid spaces are not pathognomonic for child abuse. AJNR Am J Neuroradiol. 2006;27(8):1725–8.PubMed McNeely PD, Atkinson JD, Saigal G, O’Gorman AM, Farmer JP. Subdural hematomas in infants with benign enlargement of the subarachnoid spaces are not pathognomonic for child abuse. AJNR Am J Neuroradiol. 2006;27(8):1725–8.PubMed
33.
go back to reference Hubbard D, Tobias JD. Intracerebral hemorrhage due to hemorrhagic disease of the newborn and failure to administer vitamin K at birth. South Med J. 2006;99(11):1216–20.PubMed Hubbard D, Tobias JD. Intracerebral hemorrhage due to hemorrhagic disease of the newborn and failure to administer vitamin K at birth. South Med J. 2006;99(11):1216–20.PubMed
34.
go back to reference Per H, Kumandas S, Ozdemir MA, Gumus H, Karakukcu M. Intracranial hemorrhage due to late hemorrhagic disease in two siblings. J Emerg Med. 2006;31(1):49–52.CrossRefPubMed Per H, Kumandas S, Ozdemir MA, Gumus H, Karakukcu M. Intracranial hemorrhage due to late hemorrhagic disease in two siblings. J Emerg Med. 2006;31(1):49–52.CrossRefPubMed
35.
go back to reference Feldman KW, Bethel R, Shugerman RP, Grossman DC, Grady MS, Ellenbogen RG. The cause of infant and toddler subdural hemorrhage: a prospective study. Pediatrics. 2001;108(3):636–46.CrossRefPubMed Feldman KW, Bethel R, Shugerman RP, Grossman DC, Grady MS, Ellenbogen RG. The cause of infant and toddler subdural hemorrhage: a prospective study. Pediatrics. 2001;108(3):636–46.CrossRefPubMed
36.
go back to reference Trenchs V, Curcoy AI, Navarro R, Pou J. Subdural haematomas and physical abuse in the first two years of life. Pediatr Neurosurg. 2007;43(5):352–7.CrossRefPubMed Trenchs V, Curcoy AI, Navarro R, Pou J. Subdural haematomas and physical abuse in the first two years of life. Pediatr Neurosurg. 2007;43(5):352–7.CrossRefPubMed
37.
go back to reference Twomey EL, Naughten ER, Donoghue VB, Ryan S. Neuroimaging findings in glutaric aciduria type 1. Pediatr Radiol. 2003;33(12):823–30.CrossRefPubMed Twomey EL, Naughten ER, Donoghue VB, Ryan S. Neuroimaging findings in glutaric aciduria type 1. Pediatr Radiol. 2003;33(12):823–30.CrossRefPubMed
38.
go back to reference Frasier LD, Rauth-Farley K, Alexander R, Parrish R, editors. Abusive head trauma in infants and children: a medical, legal, and forensic reference. 1st ed. St. Louis: GW Medical Publishing Inc; 2006. Frasier LD, Rauth-Farley K, Alexander R, Parrish R, editors. Abusive head trauma in infants and children: a medical, legal, and forensic reference. 1st ed. St. Louis: GW Medical Publishing Inc; 2006.
Metadata
Title
Neuroimaging of abusive head trauma
Authors
Gary L. Hedlund
Lori D. Frasier
Publication date
01-12-2009
Publisher
Humana Press Inc
Published in
Forensic Science, Medicine and Pathology / Issue 4/2009
Print ISSN: 1547-769X
Electronic ISSN: 1556-2891
DOI
https://doi.org/10.1007/s12024-009-9132-6

Other articles of this Issue 4/2009

Forensic Science, Medicine and Pathology 4/2009 Go to the issue