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Endocrine
Published in: Endocrine 1/2017

01-04-2017 | Original Article

Periodontitis is associated with diabetic retinopathy in non-obese adults

Authors: Su Jeong Song, Seong-su Lee, Kyungdo Han, Jun-Beom Park

Published in: Endocrine | Issue 1/2017

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Abstract

Purpose

Patients with diabetes retinopathy appear to show increased susceptibility to periodontal disease. This study was performed to assess the relationship between periodontitis and the prevalence of diabetic retinopathy in a large probability sample of the Korean population. A subgroup analysis was performed using body mass index <25 kg/m2 as the criterion to evaluate the effect of obesity on this relationship.

Methods

This study is based on data from the Korean National Health and Nutrition Examination Survey of the Korean population, conducted between 2008 and 2010. The presence of diabetic retinopathy in relation to demographic variables and anthropometric characteristics of the participants is presented as means with their standard errors. The presence of periodontitis and presence of retinopathy categorized by body mass index (<25 and ≥25 kg/m2) were evaluated. Multiple logistic regression analyses were used to assess the associations between periodontitis and diabetic retinopathy after adjustment with variables, including age, sex, smoking, drinking, exercise, hypertension, metabolic syndrome, HbA1c, and duration of diabetes mellitus.

Results

There was a statistically significant increase in the prevalence of periodontitis in individuals who had proliferative diabetic retinopathy. The odds ratios [95% confidence intervals] of prevalence of diabetic retinopathy were 1.193 [0.757–1.881] for the whole population after adjustments with confounding factors. Subgroup analysis after adjustments with confounding factors showed that the odds ratios [95% confidence intervals] of prevalence were 2.206 [1.114–4.366] and 0.588 [0.326–1.061] among participants with body mass index <25 kg/m2 and body mass index 37 ≥25 kg/m2, respectively.

Conclusions

The diabetic retinopathy was positively associated with the presence of periodontitis in non-obese diabetic Korean adults after adjustment with confounding variables. Our findings suggest that when a periodontist finds the presence of periodontitis in non-obese diabetic patients, timely evaluation of the patient’s ophthalmic evaluation should be 44 recommended.
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Metadata
Title
Periodontitis is associated with diabetic retinopathy in non-obese adults
Authors
Su Jeong Song
Seong-su Lee
Kyungdo Han
Jun-Beom Park
Publication date
01-04-2017
Publisher
Springer US
Published in
Endocrine / Issue 1/2017
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-016-1215-z

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