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Clinical Orthopaedics and Related Research®

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01-10-2016 | Bench to Bedside

Bench to Bedside: Platelet-rich Plasma—How Do We Adequately “Untranslate” Translational “Breakthroughs” in an After-market Setting?

Author: Benjamin K. Potter, MD

Published in: Clinical Orthopaedics and Related Research® | Issue 10/2016

Excerpt

While most of my Bench to Bedside columns focus on topics that are poised to jump from the laboratory to popular clinical practice (or soon will be), it seems important to “untranslate” something that may have infiltrated practice far ahead of adequate evidence—platelet-rich plasma (PRP). Defined simply as “a sample of autologous blood with concentrations of platelets above baseline value” [8], PRP is ostensibly rich in proteins such as platelet-derived growth factor, vascular endothelial growth factor, and human growth factor. Fibrinogen has also been detected at high concentrations in PRP. …

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Title: Bench to Bedside: Platelet-rich Plasma—How Do We Adequately “Untranslate” Translational “Breakthroughs” in an After-market Setting?
Author: Benjamin K. Potter, MD
Publication date: 01-10-2016
Publisher: Springer US
Published in: Clinical Orthopaedics and Related Research® / Issue 10/2016
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI: https://doi.org/10.1007/s11999-016-4992-z

At a glance: The STEP trials

Springer Medicine

Bench to Bedside: Platelet-rich Plasma—How Do We Adequately “Untranslate” Translational “Breakthroughs” in an After-market Setting?

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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