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Clinical Orthopaedics and Related Research®
Published in: Clinical Orthopaedics and Related Research® 1/2015

01-01-2015 | CORR Insights

CORR Insights®: The Alpha-defensin Test for Periprosthetic Joint Infection Outperforms the Leukocyte Esterase Test Strip

Author: Eoin Sheehan, MD, MCh, FRCS(Orth)

Published in: Clinical Orthopaedics and Related Research® | Issue 1/2015

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Excerpt

The diagnosis and treatment of prosthetic joint infection (PJI) is common enough to be disconcerting, seldom easy to make, and always hard on our patients. While we have myriad of implants and spacers to treat it, we lack good diagnostic tools to detect and confirm the presence of PJI. Arthroplasty surgeons should familiarize themselves with the modification of the Musculoskeletal Infection Society’s definition as formulated by the international consensus meeting on PJI in 2013 [1, 4]. …
Literature
1.
Cats-Baril W, Gehrke T, Huff K, Kendoff D, Maltenfort M, Parvizi J. International consensus on periprosthetic joint infection: Description of the consensus process. Clin Orthop Relat Res. 2013;471:4065–4075.PubMedCentralPubMedCrossRef
2.
Gristina AG. Biomaterial-centered infection: microbial adhesion versus tissue integration. Science. 1987;237:1588–1595.PubMedCrossRef
3.
Parvizi J, Jacovides C, Antoci V, Ghanem E. Diagnosis of periprosthetic joint infection: the utility of a simple yet unappreciated enzyme. J Bone Joint Surg Am. 2011;93:2242–2248.PubMed
4.
Parvizi J, Zmistowski B, Berbari EF, Bauer TW, Springer BD, Della Valle CJ, Garvin KL, Mont MA, Wongworawat MD, Zalavras CG. New definition for periprosthetic joint infection: From the workgroup of the Musculoskeletal Infection Society. Clin Orthop Relat Res. 2011;469:2992–2994.PubMedCentralPubMedCrossRef
Metadata
Title
CORR Insights®: The Alpha-defensin Test for Periprosthetic Joint Infection Outperforms the Leukocyte Esterase Test Strip
Author
Eoin Sheehan, MD, MCh, FRCS(Orth)
Publication date
01-01-2015
Publisher
Springer US
Published in
Clinical Orthopaedics and Related Research® / Issue 1/2015
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-014-3794-4

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