Skip to main content
Top
Published in: Clinical Orthopaedics and Related Research® 3/2011

01-03-2011 | Symposium: Current Concepts in Cervical Spine Surgery

Operated and Adjacent Segment Motions for Fusion versus Cervical Arthroplasty: A Pilot Study

Authors: Tomoya Terai, MD, PhD, Ahmad Faizan, PhD, Koichi Sairyo, MD, PhD, Vijay K. Goel, PhD

Published in: Clinical Orthopaedics and Related Research® | Issue 3/2011

Login to get access

Abstract

Background

Anterior cervical discectomy and fusion (ACDF) represent the standard treatment for cervical spondylolytic radiculopathy and myelopathy. To achieve solid fusion, appropriate compressive loading of the graft and stability are essential. Fusion may lead to adjacent segment degeneration. Artificial discs have been introduced as motion-preserving devices to reduce the risk of fusion-related complications.

Questions/purposes

We therefore asked: (1) Does the use of a plate reduce motion at the operated level and bone graft compression compared to fusion with bone graft alone; and (2) is adjacent-segment motion higher after fusion with a plate?

Methods

Motions and compressive loads in the graft were quantified for intact, C4–C5 ACDF without and with a plate, and total disc arthroplasty in human cadaver spines.

Results

At the surgery level all motions decreased for ACDF with a plate. The motions were similar to intact motions after total disc arthroplasty. The motions across the adjacent segment increased after fusion in all loading modes except lateral bending and were closer to the intact for the total disc arthroplasty case. The plate maintained a compressive load on the graft with a maximum increase in extension.

Conclusions

Unlike fusion, the arthroplasty can restore motion to normal at the surgery and adjacent segments, compared to fusion cases. A cervical plate with a precompression of the graft provides enhanced stability and fusion due to improved compression.

Clinical Relevance

Our findings support the clinical observations that fusion may lead to the degeneration of the adjacent segments. Disc arthroplasty may be able to circumvent the adjacent segment degeneration.
Literature
1.
go back to reference Aebi M, Zuber K, Marchesi D. Treatment of cervical spine injuries with anterior plating indications, techniques, and results. Spine (Phila Pa 1976). 1991;16(3 suppl):S38–S45. Aebi M, Zuber K, Marchesi D. Treatment of cervical spine injuries with anterior plating indications, techniques, and results. Spine (Phila Pa 1976). 1991;16(3 suppl):S38–S45.
2.
3.
go back to reference Bohler J. Immediate and early treatment of traumatic paraplegias [in German]. Z Orthop Ihre Grenzgeb. 1967;103:512–529.PubMed Bohler J. Immediate and early treatment of traumatic paraplegias [in German]. Z Orthop Ihre Grenzgeb. 1967;103:512–529.PubMed
4.
go back to reference Branch CL Jr. Anterior cervical fusion: the case for fusion without plating. Clin Neurosurg. 1999;45:22–24.PubMed Branch CL Jr. Anterior cervical fusion: the case for fusion without plating. Clin Neurosurg. 1999;45:22–24.PubMed
5.
go back to reference Brodke DS, Gollogly S, Alexander Mohr R, Nguyen BK, Dailey AT, Bachus KN. Dynamic cervical plates: biomechanical evaluation of load sharing and stiffness. Spine (Phila Pa 1976). 2001;26:1324–1329. Brodke DS, Gollogly S, Alexander Mohr R, Nguyen BK, Dailey AT, Bachus KN. Dynamic cervical plates: biomechanical evaluation of load sharing and stiffness. Spine (Phila Pa 1976). 2001;26:1324–1329.
6.
go back to reference Brodke DS, Gollogly S, Bachus KN, Alexander Mohr R, Nguyen BK. Anterior thoracolumbar instrumentation: stiffness and load sharing characteristics of plate and rod systems. Spine (Phila Pa 1976). 2003;28:1794–1801. Brodke DS, Gollogly S, Bachus KN, Alexander Mohr R, Nguyen BK. Anterior thoracolumbar instrumentation: stiffness and load sharing characteristics of plate and rod systems. Spine (Phila Pa 1976). 2003;28:1794–1801.
7.
go back to reference Bryan VE Jr. Cervical motion segment replacement. Eur Spine J. 2002;11(Suppl 2):S92–S97.PubMed Bryan VE Jr. Cervical motion segment replacement. Eur Spine J. 2002;11(Suppl 2):S92–S97.PubMed
8.
go back to reference Caspar W, Barbier DD, Klara PM. Anterior cervical fusion and Caspar plate stabilization for cervical trauma. Neurosurgery. 1989;25:491–502.CrossRefPubMed Caspar W, Barbier DD, Klara PM. Anterior cervical fusion and Caspar plate stabilization for cervical trauma. Neurosurgery. 1989;25:491–502.CrossRefPubMed
9.
go back to reference Caspar W, Geisler FA, Pitzer T, Johnson TA. Anterior cervical plate stabilization in one- and two-level degenerative disease: overtreatment or benefit? J Spinal Disord. 1998;11:1–11.CrossRefPubMed Caspar W, Geisler FA, Pitzer T, Johnson TA. Anterior cervical plate stabilization in one- and two-level degenerative disease: overtreatment or benefit? J Spinal Disord. 1998;11:1–11.CrossRefPubMed
10.
go back to reference Chang UK, Kim DH, Lee MC, Willenberg R, Kim SH, Lim J. Changes in adjacent-level disc pressure and facet joint force after cervical arthroplasty compared with cervical discectomy and fusion. J Neurosurg Spine. 2007;7:33–39.CrossRefPubMed Chang UK, Kim DH, Lee MC, Willenberg R, Kim SH, Lim J. Changes in adjacent-level disc pressure and facet joint force after cervical arthroplasty compared with cervical discectomy and fusion. J Neurosurg Spine. 2007;7:33–39.CrossRefPubMed
11.
go back to reference Cloward R. Treatment of acute fractures and fracture dislocations of the cervical spine by vertebral body fusion: a report of 11 cases. J Neurosurg. 1961;18:205–209. Cloward R. Treatment of acute fractures and fracture dislocations of the cervical spine by vertebral body fusion: a report of 11 cases. J Neurosurg. 1961;18:205–209.
12.
go back to reference Crawford NR, Peles JD, Dickman CA. The spinal lax zone and neutral zone: measurement techniques and parameter comparisons. J Spinal Disord. 1998;11:416–429.CrossRefPubMed Crawford NR, Peles JD, Dickman CA. The spinal lax zone and neutral zone: measurement techniques and parameter comparisons. J Spinal Disord. 1998;11:416–429.CrossRefPubMed
13.
go back to reference DiAngelo DJ, Foley KT, Morrow BR, Schwab JS, Song J, German JW, Blair E. In vitro biomechanics of cervical disc arthroplasty with the ProDisc-C total disc implant. Neurosurg Focus. 2004:17:E7.PubMed DiAngelo DJ, Foley KT, Morrow BR, Schwab JS, Song J, German JW, Blair E. In vitro biomechanics of cervical disc arthroplasty with the ProDisc-C total disc implant. Neurosurg Focus. 2004:17:E7.PubMed
14.
go back to reference DiAngelo DJ, Roberston JT, Metcalf NH, McVay BJ, Davis RC. Biomechanical testing of an artificial cervical joint and an anterior cervical plate. J Spinal Disord Tech. 2003:16;314–323.PubMed DiAngelo DJ, Roberston JT, Metcalf NH, McVay BJ, Davis RC. Biomechanical testing of an artificial cervical joint and an anterior cervical plate. J Spinal Disord Tech. 2003:16;314–323.PubMed
15.
go back to reference Dmitriev AE, Cunningham BW, Hu N, Sell G, Vigna F, McAfee PC. Adjacent level intradiscal pressure and segmental kinematics following a cervical total disc arthroplasty: an in vitro human cadaveric model. Spine (Phila Pa 1976). 2005;30:1165–1172. Dmitriev AE, Cunningham BW, Hu N, Sell G, Vigna F, McAfee PC. Adjacent level intradiscal pressure and segmental kinematics following a cervical total disc arthroplasty: an in vitro human cadaveric model. Spine (Phila Pa 1976). 2005;30:1165–1172.
16.
go back to reference Duggal N, Rabin D, Chamberlain RH, Baek S, Crawford NR. Traumatic loading of the Bryan cervical disc prosthesis: an in vitro study. Neurosurgery. 2007;60:388–392; discussion 392–393. Duggal N, Rabin D, Chamberlain RH, Baek S, Crawford NR. Traumatic loading of the Bryan cervical disc prosthesis: an in vitro study. Neurosurgery. 2007;60:388–392; discussion 392–393.
17.
go back to reference Goel VK, Panjabi MM, Patwardhan AG, Dooris AP, Serhan H. Test protocols for spinal implants. J Bone Joint Surg Am. 2006:88;103–109.CrossRefPubMed Goel VK, Panjabi MM, Patwardhan AG, Dooris AP, Serhan H. Test protocols for spinal implants. J Bone Joint Surg Am. 2006:88;103–109.CrossRefPubMed
18.
go back to reference Goffin J, Casey A, Kehr P, Liebig K, Lind B, Logroscino C, Pointillart V, Van Calenbergh F, van Loon J. Preliminary clinical experience with the Bryan Cervical Disc Prosthesis. Neurosurgery. 2002;51:840–845; discussion 845–847. Goffin J, Casey A, Kehr P, Liebig K, Lind B, Logroscino C, Pointillart V, Van Calenbergh F, van Loon J. Preliminary clinical experience with the Bryan Cervical Disc Prosthesis. Neurosurgery. 2002;51:840–845; discussion 845–847.
19.
20.
go back to reference Harrop JS, Youssef JA, Maltenfort M, Vorwald P, Jabbour P, Bono CM, Goldfarb N, Vaccaro AR, Hilibrand AS. 2008 Lumbar adjacent segment degeneration and disease after arthrodesis and total disc arthroplasty. Spine (Phila Pa 1976). 33:1701–1707. Harrop JS, Youssef JA, Maltenfort M, Vorwald P, Jabbour P, Bono CM, Goldfarb N, Vaccaro AR, Hilibrand AS. 2008 Lumbar adjacent segment degeneration and disease after arthrodesis and total disc arthroplasty. Spine (Phila Pa 1976). 33:1701–1707.
21.
go back to reference Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH. Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg Am. 1999;81:519–528.PubMed Hilibrand AS, Carlson GD, Palumbo MA, Jones PK, Bohlman HH. Radiculopathy and myelopathy at segments adjacent to the site of a previous anterior cervical arthrodesis. J Bone Joint Surg Am. 1999;81:519–528.PubMed
22.
go back to reference Kaiser MG, Haid RW, Subach BR, Barnes B, Rodts GE. Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft. Neurosurgery. 2002;50:229–236.CrossRefPubMed Kaiser MG, Haid RW, Subach BR, Barnes B, Rodts GE. Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft. Neurosurgery. 2002;50:229–236.CrossRefPubMed
23.
go back to reference Kotani Y, Abumi K, Shikinami Y, Takada T, Kadoya K, Shimamoto N, Ito M, Kadosawa T, Fujinaga T, Kaneda K. Artificial intervertebral disc replacement using bioactive three-dimensional fabric: design, development, and preliminary animal study. Spine (Phila Pa 1976). 2002:27;929–935; discussion 935–936. Kotani Y, Abumi K, Shikinami Y, Takada T, Kadoya K, Shimamoto N, Ito M, Kadosawa T, Fujinaga T, Kaneda K. Artificial intervertebral disc replacement using bioactive three-dimensional fabric: design, development, and preliminary animal study. Spine (Phila Pa 1976). 2002:27;929–935; discussion 935–936.
24.
go back to reference McAfee PC, Cunningham B, Dmitriev A, Hu N, Woo Kim S, Cappuccino A, Pimenta L. Cervical disc replacement-porous coated motion prosthesis: a comparative biomechanical analysis showing the key role of the posterior longitudinal ligament. Spine (Phila Pa 1976). 2003;28:S176–S185. McAfee PC, Cunningham B, Dmitriev A, Hu N, Woo Kim S, Cappuccino A, Pimenta L. Cervical disc replacement-porous coated motion prosthesis: a comparative biomechanical analysis showing the key role of the posterior longitudinal ligament. Spine (Phila Pa 1976). 2003;28:S176–S185.
25.
go back to reference Miura T, Panjabi MM, Cripton PA. A method to simulate in vivo cervical spine kinematics using in vitro compressive preload. Spine (Phila Pa 1976). 2002;27:43–48. Miura T, Panjabi MM, Cripton PA. A method to simulate in vivo cervical spine kinematics using in vitro compressive preload. Spine (Phila Pa 1976). 2002;27:43–48.
26.
go back to reference Moreland DB, Asch HL, Clabeaux DE, Castiglia GJ, Czajka GA, Lewis PJ, Egnatchik JG, Cappuccino A, Huynh L. Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft. Spine J. 2004;4:184–191.CrossRefPubMed Moreland DB, Asch HL, Clabeaux DE, Castiglia GJ, Czajka GA, Lewis PJ, Egnatchik JG, Cappuccino A, Huynh L. Anterior cervical discectomy and fusion with implantable titanium cage: initial impressions, patient outcomes and comparison to fusion with allograft. Spine J. 2004;4:184–191.CrossRefPubMed
27.
go back to reference Nabhan A, Ahlhelm F, Shariat K, Pitzen T, Steimer O, Steudel WI, Pape D. The ProDisc-C prosthesis: clinical and radiological experience 1 year after surgery. Spine (Phila Pa 1976). 2007;32:1935–1941. Nabhan A, Ahlhelm F, Shariat K, Pitzen T, Steimer O, Steudel WI, Pape D. The ProDisc-C prosthesis: clinical and radiological experience 1 year after surgery. Spine (Phila Pa 1976). 2007;32:1935–1941.
28.
go back to reference Ordway NR, Fayyazi AH, Abjornson C, Calabrese J, Park S, Fredrickson B, Yonemura K, Yuan HA. Twelve month follow up of lumbar spine range of motion following intervertebral disc replacement using radiostereometric analysis. SAS J. 2008:2;9–15.CrossRef Ordway NR, Fayyazi AH, Abjornson C, Calabrese J, Park S, Fredrickson B, Yonemura K, Yuan HA. Twelve month follow up of lumbar spine range of motion following intervertebral disc replacement using radiostereometric analysis. SAS J. 2008:2;9–15.CrossRef
29.
go back to reference Panjabi MM, Krag M, Summers D, Videman T. Biomechanical time-tolerance of fresh cadaveric human spine specimens. J Orthop Res. 1985;3:292–300.CrossRefPubMed Panjabi MM, Krag M, Summers D, Videman T. Biomechanical time-tolerance of fresh cadaveric human spine specimens. J Orthop Res. 1985;3:292–300.CrossRefPubMed
30.
go back to reference Pickett GE, Rouleau JP, Duggal N. Kinematic analysis of the cervical spine following implantation of an artificial cervical disc. Spine (Phila Pa 1976). 2005;30:1949–1954. Pickett GE, Rouleau JP, Duggal N. Kinematic analysis of the cervical spine following implantation of an artificial cervical disc. Spine (Phila Pa 1976). 2005;30:1949–1954.
31.
go back to reference Puttlitz CM, Rousseau MA, Xu Z, Hu S, Tay BK, Lotz JC. Intervertebral disc replacement maintains cervical spine kinetics. Spine (Phila Pa 1976). 2004;29:2809–2814. Puttlitz CM, Rousseau MA, Xu Z, Hu S, Tay BK, Lotz JC. Intervertebral disc replacement maintains cervical spine kinetics. Spine (Phila Pa 1976). 2004;29:2809–2814.
32.
go back to reference Rabin D, Pickett GE, Bisnaire L, Duggal N. The kinematics of anterior cervical discetomy and fusion versus artificial disc: a pilot study. Neurosurgery. 2007:61,100–104; discussion 104–105. Rabin D, Pickett GE, Bisnaire L, Duggal N. The kinematics of anterior cervical discetomy and fusion versus artificial disc: a pilot study. Neurosurgery. 2007:61,100–104; discussion 104–105.
33.
go back to reference Robertson JT, Metcalf NH. Long-term outcome after implantation of the Prestige I disc in an end-stage indication: 4-year results from a pilot study. Neurosurg Focus. 2004;17:E10.CrossRefPubMed Robertson JT, Metcalf NH. Long-term outcome after implantation of the Prestige I disc in an end-stage indication: 4-year results from a pilot study. Neurosurg Focus. 2004;17:E10.CrossRefPubMed
34.
go back to reference Robinson R, Smith G. Anterolateral cervical disk removing and interbody fusion for cervical disk syndrome. Bull Johns Hopkins Hosp. 1955;96:223–224. Robinson R, Smith G. Anterolateral cervical disk removing and interbody fusion for cervical disk syndrome. Bull Johns Hopkins Hosp. 1955;96:223–224.
35.
go back to reference Samartzis D, Shen FH, Lyon C, Phillips M, Goldberg EJ, An HS. Does rigid instrumentation increase the fusion rate in one-level anterior cervical discectomy and fusion? Spine J. 2004;4:636–643.CrossRefPubMed Samartzis D, Shen FH, Lyon C, Phillips M, Goldberg EJ, An HS. Does rigid instrumentation increase the fusion rate in one-level anterior cervical discectomy and fusion? Spine J. 2004;4:636–643.CrossRefPubMed
36.
go back to reference Wang JC, McDonough PW, Endow KK, Kanim LE, Delamarter RB. The effect of cervical plating on single-level anterior cervical discectomy and fusion. J Spinal Disord. 1999;12:467–471.CrossRefPubMed Wang JC, McDonough PW, Endow KK, Kanim LE, Delamarter RB. The effect of cervical plating on single-level anterior cervical discectomy and fusion. J Spinal Disord. 1999;12:467–471.CrossRefPubMed
37.
go back to reference Yang S, Wu X, Hu Y, Li J, Liu G, Xu W, Yang C, Ye S. 2008 Early and intermediate follow-up results after treatment of degenerative disc disease with the Bryan cervical disc prosthesis: single- and multiple-level. Spine (Phila Pa 1976). 2008;33:E371–E377. Yang S, Wu X, Hu Y, Li J, Liu G, Xu W, Yang C, Ye S. 2008 Early and intermediate follow-up results after treatment of degenerative disc disease with the Bryan cervical disc prosthesis: single- and multiple-level. Spine (Phila Pa 1976). 2008;33:E371–E377.
Metadata
Title
Operated and Adjacent Segment Motions for Fusion versus Cervical Arthroplasty: A Pilot Study
Authors
Tomoya Terai, MD, PhD
Ahmad Faizan, PhD
Koichi Sairyo, MD, PhD
Vijay K. Goel, PhD
Publication date
01-03-2011
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 3/2011
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-010-1646-4

Other articles of this Issue 3/2011

Clinical Orthopaedics and Related Research® 3/2011 Go to the issue