Skip to main content
Top
Published in: Clinical Orthopaedics and Related Research® 5/2011

01-05-2011 | Symposium: Myelomeningocele

Hip and Spine Surgery is of Questionable Value in Spina Bifida: An Evidence-based Review

Author: James G. Wright, MD, MPH, FRCSC

Published in: Clinical Orthopaedics and Related Research® | Issue 5/2011

Login to get access

Abstract

Background

Although many children with spina bifida and associated scoliosis or dislocated hips undergo spine or hip surgery, the benefits are uncertain.

Questions/purposes

The purpose was to perform an evidence-based review on the benefits and risks of surgery for dislocated hips and scoliosis in spina bifida.

Methods

I performed a Medline® and Embase® search from 1950 to 2009 for Level I to Level III studies investigating the benefits and risks of surgery for scoliosis and hip dislocation in patients with spina bifida. When available, I extracted types of surgery, complication rates, functional outcomes of seating, walking, and overall physical function. All treatment recommendations received a Grade of Recommendation: Grade A (consistent Level I studies); Grade B (consistent Level II and III studies); Grade C (consistent level IV and V studies); or Grade I (insufficient or contradictory studies).

Results

Combined anterior and posterior surgery had lower rates of nonunion for scoliosis. Although there may be some benefit in seating, overall physical function measured in a different and nonstandardized fashion was not much changed and major complication rates, including nonunion and infections for scoliosis surgery, exceed 50% in several studies. For dislocated hips, the impact on walking ability appears related to contracture (not dislocation). Surgery for hip dislocation did not improve walking ability. The literature provides no guidance on the best treatment for unilateral dislocation.

Conclusions

The benefits of scoliosis surgery are uncertain (Grade I). Spine surgery, if performed, should be anterior and posterior (Grade B). An all-pedicle approach for scoliosis surgery may be effective (Level I). Hip reduction surgery did not improve walking (Grade B) but may be appropriate in low-level unilateral dislocation (Level I).
Appendix
Available only for authorised users
Literature
1.
go back to reference Ascani E, Bartolozzi P, Logroscino CA, Marchetti PG, Ponte A, Savini R, Travaglini F, Binazzi R, Silvertre MDI. Natural history of untreated idiopathic scoliosis after skeletal maturity. Symposium on epidemiology, Natural History and Non-operative Treatment of Idiopathic Scoliosis. Spine. 1986;11:784–789.PubMedCrossRef Ascani E, Bartolozzi P, Logroscino CA, Marchetti PG, Ponte A, Savini R, Travaglini F, Binazzi R, Silvertre MDI. Natural history of untreated idiopathic scoliosis after skeletal maturity. Symposium on epidemiology, Natural History and Non-operative Treatment of Idiopathic Scoliosis. Spine. 1986;11:784–789.PubMedCrossRef
2.
go back to reference Asher M, Olson J. Factors affecting the ambulatory status of patients with spina bifida cystica. J Bone Joint Surg Am. 1983;65:350–356.PubMed Asher M, Olson J. Factors affecting the ambulatory status of patients with spina bifida cystica. J Bone Joint Surg Am. 1983;65:350–356.PubMed
3.
go back to reference Alman BA, Bhandari M, Wright JG. Function of dislocated hips in children with lower level spina bifida. J Bone Joint Surg Br. 1996;78:294–298.PubMed Alman BA, Bhandari M, Wright JG. Function of dislocated hips in children with lower level spina bifida. J Bone Joint Surg Br. 1996;78:294–298.PubMed
4.
go back to reference Banit DM, Iwinski HJ Jr, Talwalkar V, Johnson M. Posterior spinal fusion in paralytic scoliosis and myelomeningocele. J Pediatr Orthop. 2001;21:117–125.PubMedCrossRef Banit DM, Iwinski HJ Jr, Talwalkar V, Johnson M. Posterior spinal fusion in paralytic scoliosis and myelomeningocele. J Pediatr Orthop. 2001;21:117–125.PubMedCrossRef
5.
go back to reference Banta JV, Park SM. Improvement in pulmonary function in patients having combined anterior and posterior spine fusion for myelomeningocele scoliosis. Spine (Phila Pa 1976). 1983;8:765–770. Banta JV, Park SM. Improvement in pulmonary function in patients having combined anterior and posterior spine fusion for myelomeningocele scoliosis. Spine (Phila Pa 1976). 1983;8:765–770.
6.
go back to reference Bartonek Å, Saraste H, Samuelsson L, Skoog M. Ambulation in patients with myelomeningocele: a 12-year follow-up. J Pediatr Orthop. 1999;19:202–206.PubMed Bartonek Å, Saraste H, Samuelsson L, Skoog M. Ambulation in patients with myelomeningocele: a 12-year follow-up. J Pediatr Orthop. 1999;19:202–206.PubMed
7.
go back to reference Bazih J, Gross RH. Hip surgery in the lumbar level myelomeningocele patient. J Pediatr Orthop. 1981;1:405–411.PubMedCrossRef Bazih J, Gross RH. Hip surgery in the lumbar level myelomeningocele patient. J Pediatr Orthop. 1981;1:405–411.PubMedCrossRef
8.
go back to reference Broughton NS, Menelaus MB, Cole WG, Shurtleff DB. The natural history of hip deformity in myelomeningocele. J Bone Joint Surg Br. 1993;75:760–763.PubMed Broughton NS, Menelaus MB, Cole WG, Shurtleff DB. The natural history of hip deformity in myelomeningocele. J Bone Joint Surg Br. 1993;75:760–763.PubMed
9.
go back to reference Carstens C, Paul K, Niethard FU, Pfeil J. Effect of scoliosis surgery on pulmonary function in patients with myelomeningocele. J Pediatr Orthop. 1991;11:459–464.PubMedCrossRef Carstens C, Paul K, Niethard FU, Pfeil J. Effect of scoliosis surgery on pulmonary function in patients with myelomeningocele. J Pediatr Orthop. 1991;11:459–464.PubMedCrossRef
10.
go back to reference Charney EB, Melchionni JB, Smith DR. Community ambulation by children with myelomeningocele and high-level paralysis. J Pediatr Orthop. 1991;11:579–582.PubMed Charney EB, Melchionni JB, Smith DR. Community ambulation by children with myelomeningocele and high-level paralysis. J Pediatr Orthop. 1991;11:579–582.PubMed
11.
go back to reference Crandall RC, Birkebak RC, Winter RB. The role of hip location and dislocation in the functional status of the myelodysplastic patient. A review of 100 patients. Orthopedics. 1989;12:675–684.PubMed Crandall RC, Birkebak RC, Winter RB. The role of hip location and dislocation in the functional status of the myelodysplastic patient. A review of 100 patients. Orthopedics. 1989;12:675–684.PubMed
12.
go back to reference Danzer E, Gerdes M, Bebbington MW, Sutton LN, Melchionni J, Adzick NS, Wilson RD, Johnson MP. Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagn Ther. 2009;25:47–53.PubMedCrossRef Danzer E, Gerdes M, Bebbington MW, Sutton LN, Melchionni J, Adzick NS, Wilson RD, Johnson MP. Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagn Ther. 2009;25:47–53.PubMedCrossRef
13.
go back to reference Dias L, Swaroop V. What is the optimal treatment for hip and spine in myelomeningocele? In: Wright, J, ed. Evidence-based Orthopaedics: The Best Answers to Clinical Questions. Philadelphia, PA: Elsevier; 2009:273–277. Dias L, Swaroop V. What is the optimal treatment for hip and spine in myelomeningocele? In: Wright, J, ed. Evidence-based Orthopaedics: The Best Answers to Clinical Questions. Philadelphia, PA: Elsevier; 2009:273–277.
14.
go back to reference Feiwell E, Sakai D, Blatt T. The effect of hip reduction on function in patients with myelomeningocele. Potential gains and hazards of surgical treatment. J Bone Joint Surg Am. 1978;60:169–173.PubMed Feiwell E, Sakai D, Blatt T. The effect of hip reduction on function in patients with myelomeningocele. Potential gains and hazards of surgical treatment. J Bone Joint Surg Am. 1978;60:169–173.PubMed
15.
go back to reference Fraser RK, Hoffman EB, Sparks LT, Buccimazza SS. The unstable hip and mid-lumbar myelomeningocele. J Bone Joint Surg Br. 1992;74:143–146.PubMed Fraser RK, Hoffman EB, Sparks LT, Buccimazza SS. The unstable hip and mid-lumbar myelomeningocele. J Bone Joint Surg Br. 1992;74:143–146.PubMed
16.
go back to reference Johnson C. Evidence-based practice in 5 simple steps. J Manipulative Physiol Ther. 2008;31:169–170.PubMedCrossRef Johnson C. Evidence-based practice in 5 simple steps. J Manipulative Physiol Ther. 2008;31:169–170.PubMedCrossRef
17.
go back to reference Kahanovitz N, Duncan JW. The role of scoliosis and pelvic obliquity on functional disability in myelomeningocele. Spine. 1981;6:494–497.PubMedCrossRef Kahanovitz N, Duncan JW. The role of scoliosis and pelvic obliquity on functional disability in myelomeningocele. Spine. 1981;6:494–497.PubMedCrossRef
18.
go back to reference Mazur J, Menelaus MB, Dickens DR, Doig WG. Efficacy of surgical management for scoliosis in myelomeningocele: correction of deformity and alteration of functional status. J Pediatr Orthop. 1986;6:568–575.PubMedCrossRef Mazur J, Menelaus MB, Dickens DR, Doig WG. Efficacy of surgical management for scoliosis in myelomeningocele: correction of deformity and alteration of functional status. J Pediatr Orthop. 1986;6:568–575.PubMedCrossRef
19.
go back to reference McDougall J, Miller LT. Measuring chronic health condition and disability as distinct concepts in national surveys of school-aged children in Canada: a comprehensive review with recommendations based on the ICD-10 and ICF. Disabil Rehabil. 2003;25:922–939.PubMedCrossRef McDougall J, Miller LT. Measuring chronic health condition and disability as distinct concepts in national surveys of school-aged children in Canada: a comprehensive review with recommendations based on the ICD-10 and ICF. Disabil Rehabil. 2003;25:922–939.PubMedCrossRef
20.
go back to reference Osebold WR, Mayfield JK, Winter RB, Moe JH. Surgical treatment of paralytic scoliosis associated with myelomeningocele. J Bone Joint Surg Am. 1982;64:841–856.PubMed Osebold WR, Mayfield JK, Winter RB, Moe JH. Surgical treatment of paralytic scoliosis associated with myelomeningocele. J Bone Joint Surg Am. 1982;64:841–856.PubMed
21.
go back to reference Parisini P, Greggi T, Di Silvestre M, Giardina F, Bakaloudis G. Surgical treatment of scoliosis in myelomeningocele. Stud Health Technol Inform. 2002;91:442–447.PubMed Parisini P, Greggi T, Di Silvestre M, Giardina F, Bakaloudis G. Surgical treatment of scoliosis in myelomeningocele. Stud Health Technol Inform. 2002;91:442–447.PubMed
22.
go back to reference Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn’t. BMJ. 1996;312:71–72.PubMed Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn’t. BMJ. 1996;312:71–72.PubMed
23.
go back to reference Samuelsson L, Skoog M. Ambulation in patients with myelomeningocele: a multivariate statistical analysis. J Pediatr Orthop. 1988;8:569–575.PubMedCrossRef Samuelsson L, Skoog M. Ambulation in patients with myelomeningocele: a multivariate statistical analysis. J Pediatr Orthop. 1988;8:569–575.PubMedCrossRef
24.
go back to reference Schoenmakers MA, Gulmans VA, Gooskens RH, Pruijs JE, Helders PJ. Spinal fusion in children with spina bifida: influence on ambulation level and functional abilities. Eur Spine J. 2005;14:415–422.PubMedCrossRef Schoenmakers MA, Gulmans VA, Gooskens RH, Pruijs JE, Helders PJ. Spinal fusion in children with spina bifida: influence on ambulation level and functional abilities. Eur Spine J. 2005;14:415–422.PubMedCrossRef
25.
go back to reference Sherk HH, Ames MD. Functional results of iliopsoas transfer in myelomeningocele hip dislocations. Clin Orthop Relat Res. 1978;137:181–186.PubMed Sherk HH, Ames MD. Functional results of iliopsoas transfer in myelomeningocele hip dislocations. Clin Orthop Relat Res. 1978;137:181–186.PubMed
26.
go back to reference Shurtleff DB. Myelodysplasias and Exstrophies: Significance, Prevention, and Treatment. Orlando, FL: Grune & Stratton, Inc; 1986. Shurtleff DB. Myelodysplasias and Exstrophies: Significance, Prevention, and Treatment. Orlando, FL: Grune & Stratton, Inc; 1986.
27.
go back to reference Stella G, Ascani E, Cervellati S, Bettini N, Scarsi M, Vicini M, Magillo P, Carbone M. Surgical treatment of scoliosis associated with myelomeningocele. Eur J Pediatr Surg. 1998;8(Supp I):22–25.PubMedCrossRef Stella G, Ascani E, Cervellati S, Bettini N, Scarsi M, Vicini M, Magillo P, Carbone M. Surgical treatment of scoliosis associated with myelomeningocele. Eur J Pediatr Surg. 1998;8(Supp I):22–25.PubMedCrossRef
28.
go back to reference Wai EK, Young NL, Feldman BM, Badley EM, Wright JG. The relationship between function, self-perception, and spinal deformity: implications for treatment of scoliosis in children with spina bifida. J Pediatr Orthop. 2005;25:64–69.PubMed Wai EK, Young NL, Feldman BM, Badley EM, Wright JG. The relationship between function, self-perception, and spinal deformity: implications for treatment of scoliosis in children with spina bifida. J Pediatr Orthop. 2005;25:64–69.PubMed
29.
go back to reference Ward WT, Wenger DR, Roach JW. Surgical correction of myelomeningocele scoliosis: a critical appraisal of various spinal instrumentation systems. J Pediatr Orthop. 1989;9:262–268.PubMed Ward WT, Wenger DR, Roach JW. Surgical correction of myelomeningocele scoliosis: a critical appraisal of various spinal instrumentation systems. J Pediatr Orthop. 1989;9:262–268.PubMed
30.
go back to reference Williams EN, Broughton NS, Menelaus MB. Age-related walking in children with spina bifida. Dev Med Child Neurol. 1999;41:446–449.PubMedCrossRef Williams EN, Broughton NS, Menelaus MB. Age-related walking in children with spina bifida. Dev Med Child Neurol. 1999;41:446–449.PubMedCrossRef
31.
go back to reference Wright JG. Revised grades of recommendation for summaries or reviews of orthopaedic surgical studies. J Bone Joint Surg Am. 2006;88:1161–1162. PubMed Wright JG. Revised grades of recommendation for summaries or reviews of orthopaedic surgical studies. J Bone Joint Surg Am. 2006;88:1161–1162. PubMed
32.
go back to reference Wright JG. A practical guide to assigning levels of evidence. J Bone Joint Surg Am. 2007;89:1128–1130.PubMedCrossRef Wright JG. A practical guide to assigning levels of evidence. J Bone Joint Surg Am. 2007;89:1128–1130.PubMedCrossRef
Metadata
Title
Hip and Spine Surgery is of Questionable Value in Spina Bifida: An Evidence-based Review
Author
James G. Wright, MD, MPH, FRCSC
Publication date
01-05-2011
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 5/2011
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-010-1595-y

Other articles of this Issue 5/2011

Clinical Orthopaedics and Related Research® 5/2011 Go to the issue