Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Clinical Orthopaedics and Related Research®
Published in: Clinical Orthopaedics and Related Research® 12/2009

01-12-2009 | Case Report

Case Report: Primary Squamous Cell Carcinoma of a Tarsal Bone

Authors: Czar Louie L. Gaston, MD, Ariel M. Vergel de Dios, MD, Tammy L. Dela Rosa, MD, Edward H. M. Wang, MD, MSc

Published in: Clinical Orthopaedics and Related Research® | Issue 12/2009

Login to get access

Abstract

We describe a rare case of primary squamous cell carcinoma of the cuneiform bone of the foot in a 57-year-old man. In the appendicular skeleton, epithelial carcinomas of bone are usually metastatic deposits, primary squamous cell carcinomas of bone being found more frequently in the skull. A review of the English literature revealed only two other reported cases of primary squamous cell carcinoma outside the skull—one in the ilium and one in the tibia. In our patient, extensive metastatic workup and monitoring during more than 2 years showed no primary focus, supporting the rare presentation of a primary squamous cell carcinoma of bone in the appendicular skeleton.
Literature
1.
Abbas A, Bromage JD, Stocks PJ, Al-Sarireh B. Case of the Conference: Primary squamous cell carcinoma in a long bone. J Bone Joint Surg Br. 2005;87(suppl 1):6.
2.
Bridgeman A, Wiesenfeld D, Buchanan M, Slavin J, Costello B. A primary intraosseous carcinoma of the anterior maxilla: report of a new case. Int J Oral Maxillofac Surg. 1996;25:279–281.CrossRefPubMed
3.
Gangopadhyay S, Saha S. Primary squamous cell carcinoma of bone. J Indian Med Assoc. 1997;95:521–523. PubMed
4.
Ide F, Shimoyama T, Horie N, Kaneko T. Primary intraosseous carcinoma of the mandible with probable origin from reduced enamel epithelium. J Oral Pathol Med. 1999;28:420–422.PubMed
5.
Lu C, Chang K, Liu C. Primary intraosseous carcinoma of the mandible: a case report. Chin J Oral Maxillofac Surg. 2004;15:38–47.
6.
Maheshwari AV, Chiappetta G, Kugler CD, Pitcher JD Jr, Temple HT. Metastatic skeletal disease of the foot: case reports and literature review. Foot Ankle Int. 2008;29:699–710.CrossRefPubMed
7.
Moffat DA, Wagstaff SA. Squamous cell carcinoma of the temporal bone. Curr Opin Otolaryngol Head Neck Surg. 2003;11:107–111.CrossRefPubMed
8.
Moon NF. Adamantinoma of the appendicular skeleton: a statistical review of reported cases and inclusion of 10 new cases. Clin Orthop Relat Res. 1965;43:189–213.CrossRefPubMed
9.
Mori H, Yamamoto S, Hiramatsu K, Miura T, Moon NF. Adamantinoma of the tibia: ultrastructural and immunohistochemic study with reference to histogenesis. Clin Orthop Relat Res. 1984;190:299–309.PubMed
10.
Murillo-Cortes J, Etayo-Perez A, Sebastian-Lopez C, Martino-Gorbea R, Rodriquez-Cortel JM. Primary intraosseous carcinoma arising in a mandibular cyst. Med Oral. 2002;7:370–374.PubMed
11.
Punnya A, Kumar G, Rekha K, Vandana R. Primary intraosseous odontogenic carcinoma with osteoid/dentinoid formation. J Oral Pathol Med. 2004;33:121–124.CrossRefPubMed
12.
Rosai J. Adamantinoma of the tibia: electron microscopic evidence of its epithelial origin. Am J Clin Pathol. 1969;51:786–792.PubMed
13.
Ryrie BJ. Adamantinoma of the tibia: aetiology and pathogenesis. BMJ. 1932;2:1000–1003.CrossRef
14.
Zindrick MR, Young MP, Daley RJ, Light TR. Metastatic tumors of the foot: case report and literature review. Clin Orthop Relat Res. 1982;170:219–225.PubMed
15.
Zwetyenga N, Pinsolle J, Rivel J, Majoufre-Lefebvre C, Faucher A, Pinsolle V. Primary intraosseous carcinoma of the jaws. Arch Otolaryngol Head Neck Surg. 2001;127:794–797.PubMed
Metadata
Title
Case Report: Primary Squamous Cell Carcinoma of a Tarsal Bone
Authors
Czar Louie L. Gaston, MD
Ariel M. Vergel de Dios, MD
Tammy L. Dela Rosa, MD
Edward H. M. Wang, MD, MSc
Publication date
01-12-2009
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 12/2009
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-009-0926-3

Other articles of this Issue 12/2009

Clinical Orthopaedics and Related Research® 12/2009 Go to the issue

Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors

Starch-poly-є-caprolactone Microparticles Reduce the Needed Amount of BMP-2

Basic Research

Clinical Anatomy of the Quadriceps Femoris and Extensor Apparatus of the Knee

Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors

Synthetic Alginate is a Carrier of OP-1 for Bone Induction

Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors

Nonviral Delivery of Basic Fibroblast Growth Factor Gene to Bone Marrow Stromal Cells

Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors

Levels of Expression for BMP-7 and Several BMP Antagonists May Play an Integral Role in a Fracture Nonunion: A Pilot Study

Symposium: Tribute to Dr. Marshall Urist: Musculoskeletal Growth Factors

Mesenchymal Stem Cell and Nucleus Pulposus Cell Coculture Modulates Cell Profile