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01-04-2024 | Opioids | Chronic Pain Medicine (O Viswanath, Section Editor)

Assessing Risk Factors and Comorbidities in the Treatment of Chronic Pain: A Narrative Review

Authors: Sage V. Hebert, Melanie A. Green, Sydney A. Mashaw, William D. Brouillette, Angela Nguyen, Kylie Dufrene, Anitha Shelvan, Shilpadevi Patil, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

Published in: Current Pain and Headache Reports

Abstract

Purpose of Review

Chronic pain affects a significant portion of the population globally, making it a leading cause of disability. Understanding the multifaceted nature of chronic pain, its various types, and the intricate relationship it shares with risk factors, comorbidities, and mental health issues like depression and anxiety is critical for comprehensive patient care. Factors such as socioeconomic status (SES), age, gender, and obesity collectively add layers of complexity to chronic pain experiences and pose management challenges.

Recent Findings

Low SES presents barriers to effective pain care, while gender differences and the prevalence of chronic pain in aging adults emphasize the need for tailored approaches. The association between chronic pain and physical comorbidities like cardiovascular disease, chronic obstructive pulmonary disease (COPD), and diabetes mellitus reveals shared risk factors and further highlights the importance of integrated treatment strategies. Chronic pain and mental health are intricately linked through biochemical mechanisms, profoundly affecting overall quality of life. This review explores pharmacologic treatment for chronic pain, particularly opioid analgesia, with attention to the risk of substance misuse and the ongoing opioid epidemic. We discuss the potential role of medical cannabis as an alternative treatment with a nuanced perspective on its impact on opioid use.

Summary

Addressing the totality and complexity of pain states is crucial to individualizing chronic pain management. With different types of pain having different underlying mechanisms, considerations should be made when approaching their treatment. Moreover, the synergistic relationship that pain states can have with other comorbidities further complicates chronic pain conditions.

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Title: Assessing Risk Factors and Comorbidities in the Treatment of Chronic Pain: A Narrative Review
Authors: Sage V. Hebert
Melanie A. Green
Sydney A. Mashaw
William D. Brouillette
Angela Nguyen
Kylie Dufrene
Anitha Shelvan
Shilpadevi Patil
Shahab Ahmadzadeh
Sahar Shekoohi
Alan D. Kaye
Publication date: 01-04-2024
Publisher: Springer US
Keywords: Opioids
Opioids
Obesity
Obesity
Anxiety
Affective Disorder
Affective Disorder
Published in: Current Pain and Headache Reports
Print ISSN: 1531-3433
Electronic ISSN: 1534-3081
DOI: https://doi.org/10.1007/s11916-024-01249-z

At a glance: The STEP trials

Springer Medicine

Assessing Risk Factors and Comorbidities in the Treatment of Chronic Pain: A Narrative Review

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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