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Published in: Current Pain and Headache Reports 5/2018

01-05-2018 | Childhood and Adolescent Headache (S Evers, Section Editor)

The Evidence for the Role of Nutraceuticals in the Management of Pediatric Migraine: a Review

Author: Serena L. Orr

Published in: Current Pain and Headache Reports | Issue 5/2018

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Abstract

Purpose of Review

Nutraceuticals are a form of complementary and alternative medicine that is commonly used by children and adolescents with migraine. In this review, observational studies, randomized controlled trials, systematic reviews, and meta-analyses on the efficacy and safety of single compound nutraceuticals for the management of migraine in children and adolescents were identified through a literature search of MEDLINE, Embase, and EBM Reviews—Cochrane Central Register of Controlled Trials.

Recent Findings

Twenty-one studies were reviewed, of which 11 were observational studies, 7 were randomized controlled trials, and 3 were systematic reviews. Six different nutraceuticals were included in the review: vitamin D, riboflavin, coenzyme Q10, magnesium, butterbur, and polyunsaturated fatty acids. All but three of the studies assessed the role of nutraceuticals in migraine prevention, while three studies evaluated the role of intravenous magnesium for acute migraine management. Overall, the quality and size of the studies were limited.

Summary

Due to low quality evidence and limited studies, no definite conclusions can be drawn on the efficacy of nutraceuticals for the treatment of pediatric migraine. Future studies are warranted in order to establish evidence upon which to define the role of nutraceuticals in this patient population.
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Metadata
Title
The Evidence for the Role of Nutraceuticals in the Management of Pediatric Migraine: a Review
Author
Serena L. Orr
Publication date
01-05-2018
Publisher
Springer US
Published in
Current Pain and Headache Reports / Issue 5/2018
Print ISSN: 1531-3433
Electronic ISSN: 1534-3081
DOI
https://doi.org/10.1007/s11916-018-0692-6

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