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Current Pain and Headache Reports

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01-08-2017 | Migraine and Beyond (R Cowan, Section Editor)

Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension

Authors: Peter G. Kranz, Michael D. Malinzak, Timothy J. Amrhein, Linda Gray

Published in: Current Pain and Headache Reports | Issue 8/2017

Abstract

Purpose of Review

The purpose of this study is to provide an update on recent developments in the understanding, diagnosis, and treatment of spontaneous intracranial hypotension (SIH).

Recent Findings

SIH is an important cause of headaches caused by spinal cerebrospinal fluid (CSF) leaks, with an increasingly broad spectrum of clinical presentations and diagnostic findings. A simple conception of the condition as being defined by the presence of low CSF pressure is no longer sufficient or accurate. A number of etiologies for spinal CSF leaks have been identified, including the recent discovery of CSF-venous fistulas, and these various etiologies may require different diagnostic and therapeutic pathways in order to affect a cure.

Summary

Familiarity with the spectrum of presentations and causes of SIH is critical to accurate and timely diagnosis and management. Challenges exist in both diagnosis and treatment, and require understanding of the underlying pathogenesis of the condition in order to appropriately select testing and treatment. Prospective studies are needed going forward in order to inform workup and guide treatment decisions.

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Title: Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension
Authors: Peter G. Kranz
Michael D. Malinzak
Timothy J. Amrhein
Linda Gray
Publication date: 01-08-2017
Publisher: Springer US
Published in: Current Pain and Headache Reports / Issue 8/2017
Print ISSN: 1531-3433
Electronic ISSN: 1534-3081
DOI: https://doi.org/10.1007/s11916-017-0639-3

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Update on the Diagnosis and Treatment of Spontaneous Intracranial Hypotension

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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