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Published in: Current Neurology and Neuroscience Reports 10/2014

01-10-2014 | Neurology of Systemic Disease (J Biller, Section Editor)

Neurologic Manifestations of Gastrointestinal and Liver Diseases

Authors: José M. Ferro, Sofia Oliveira

Published in: Current Neurology and Neuroscience Reports | Issue 10/2014

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Abstract

Hepatic and gastrointestinal disorders can produce a wide spectrum of neurologic complications both affecting the central nervous system (CNS) and the peripheral nervous system. These manifestations range in severity from coma in acute liver failure and acute pancreatitis, to minor cognitive changes in chronic portosystemic encephalopathy and hepatitis C. Cerebrovascular diseases can complicate hepatitis C infection and inflammatory bowel disease. Demyelinating disorders may co-exist with inflammatory bowel disease. Anti-tumor necrosis factor alpha drugs may induce demyelination. Ataxia may occur in malabsorption syndromes and in gluten related disorders. Characteristic movement disorders are key features of acquired hepatocerebral degeneration and of Whipple disease. Multiple types of neuropathy can be found in association with hepatitis, inflammatory bowel disease and gluten related disorders.
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Metadata
Title
Neurologic Manifestations of Gastrointestinal and Liver Diseases
Authors
José M. Ferro
Sofia Oliveira
Publication date
01-10-2014
Publisher
Springer US
Published in
Current Neurology and Neuroscience Reports / Issue 10/2014
Print ISSN: 1528-4042
Electronic ISSN: 1534-6293
DOI
https://doi.org/10.1007/s11910-014-0487-z

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