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Current Bladder Dysfunction Reports

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01-06-2019 | Isoniazid | Inflammatory/Infectious Bladder Disorders (MS Mourad, Section Editor)

Effects and Complications of Intravesical Instillation of Bacillus Calmette-Guerin Therapy

Authors: J. Spencer Keith, Mahmoud I. Khalil, Mohamed H. Kamel, Rodney Davis, Ehab Eltahawy

Published in: Current Bladder Dysfunction Reports | Issue 2/2019

Abstract

Purpose of Review

This review will address the current literature available regarding complications after intravesical Bacillus Calmette-Guerin (BCG) therapy for bladder cancer. Topics include intravesical BCG therapy–related complications, role of BCG therapy in immunosuppression, and future directions in the context of BCG-related complications.

Recent Findings

There are several new reviews and case reports discussing unique complications following intravesical BCG therapy that should raise awareness of possible short-term and long-term effects after using this common treatment modality in bladder cancer patients.

Summary

Since intravesical BCG is a common treatment option for non-muscle invasive bladder cancer and can cause a variety of complications, it is important to recognize this aspect of the patient’s history when evaluating patients who present with symptoms similar to the ones discussed in this review. This will allow for prompt delivery of treatment as well as preventing unnecessary morbidity and mortality.

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Title: Effects and Complications of Intravesical Instillation of Bacillus Calmette-Guerin Therapy
Authors: J. Spencer Keith
Mahmoud I. Khalil
Mohamed H. Kamel
Rodney Davis
Ehab Eltahawy
Publication date: 01-06-2019
Publisher: Springer US
Keyword: Isoniazid
Published in: Current Bladder Dysfunction Reports / Issue 2/2019
Print ISSN: 1931-7212
Electronic ISSN: 1931-7220
DOI: https://doi.org/10.1007/s11884-019-00506-x

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Springer Medicine

Effects and Complications of Intravesical Instillation of Bacillus Calmette-Guerin Therapy

Abstract

Purpose of Review

Recent Findings

Summary

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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