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Current Allergy and Asthma Reports
Published in: Current Allergy and Asthma Reports 9/2016

01-09-2016 | Basic and Applied Science (I Lewkowich, Section Editor)

MicroRNAs in Allergic Disease

Authors: Eishika Dissanayake, Yuzaburo Inoue

Published in: Current Allergy and Asthma Reports | Issue 9/2016

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Abstract

Purpose of Review

MicroRNAs (miRNAs) are short, single-stranded, non-coding RNAs that are increasingly being recognized as important epigenetic regulators. They have been implicated in the pathogenesis of many diseases including cancer, cardiovascular diseases, connective tissue diseases, and neuromuscular disorders.

Recent Findings

A few miRNAs have already been recognized as a core set of miRNAs important in allergic inflammation. These include let-7, miR-21, miR-142, and miR-146.

Summary

This review aims to bring together some of the recent findings on how miRNAs regulate allergic inflammation with special focus on asthma, atopic dermatitis, allergic rhinitis, and eosinophilic esophagitis. We will also touch upon extracellular miRNAs and future perspective of this field of study.
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Metadata
Title
MicroRNAs in Allergic Disease
Authors
Eishika Dissanayake
Yuzaburo Inoue
Publication date
01-09-2016
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 9/2016
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-016-0648-z

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