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Open Access 01-04-2014 | ALLERGENS (RK BUSH AND JA WOODFOLK, SECTION EDITORS)

Cross-Reactivity of Peanut Allergens

Authors: Merima Bublin, Heimo Breiteneder

Published in: Current Allergy and Asthma Reports | Issue 4/2014

Abstract

Peanut seeds are currently widely used as source of human food ingredients in the United States of America and in European countries due to their high quality protein and oil content. This article describes the classification and molecular biology of peanut seed allergens with particular reference to their cross-reactivities. Currently, the IUIS allergen nomenclature subcommittee accepts 12 peanut allergens. Two allergens belong to the cupin and four to the prolamin superfamily, and six are distributed among profilins, Bet v 1-like proteins, oleosins, and defensins. Clinical observations frequently report an association of peanut allergy with allergies to legumes, tree nuts, seeds, fruits and pollen. Molecular cross-reactivity has been described between members of the Bet v 1-like proteins, the non-specific lipid transfer proteins, and the profilins. This review also addresses the less well-studied cross-reactivity between cupin and prolamin allergens of peanuts and of other plant food sources and the recently discovered cross-reactivity between peanut allergens of unrelated protein families.

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Title: Cross-Reactivity of Peanut Allergens
Authors: Merima Bublin
Heimo Breiteneder
Publication date: 01-04-2014
Publisher: Springer US
Published in: Current Allergy and Asthma Reports / Issue 4/2014
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI: https://doi.org/10.1007/s11882-014-0426-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Cross-Reactivity of Peanut Allergens

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

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