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Published in: General Thoracic and Cardiovascular Surgery 9/2022

29-03-2022 | Original Article

Outcomes of loop technique with ring annuloplasty: a > 10-year experience

Authors: Akimasa Morisaki, Yosuke Takahashi, Hiromichi Fujii, Yoshito Sakon, Takashi Murakami, Toshihiko Shibata

Published in: General Thoracic and Cardiovascular Surgery | Issue 9/2022

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Abstract

Objective

We assessed the long-term outcomes of the loop technique with ring annuloplasty for mitral regurgitation from our > 10-year experience.

Methods

We retrospectively reviewed 362 patients who underwent the loop technique with ring annuloplasty via median sternotomy or right mini-thoracotomy for mitral regurgitation. The median follow-up duration was 4.1 years (interquartile range 2.3–5.8 years).

Results

This study involved 147 women and 215 men (median age, 66.5 years). Mitral regurgitation was caused by Barlow’s disease in 27 patients. Seven patients required reoperations (recurrent regurgitation caused by technical issues, n = 3; progression of degenerative disease, n = 4). The 5- and 10-year cumulative incidences of reoperation considering death as the competing event were 1.4% and 5.4%, respectively. The 5- and 10-year postoperative cumulative incidences of moderate-to-severe recurrent mitral regurgitation were 4.7% and 13.0%, respectively. Residual regurgitation ≥ mild (hazard ratio, 6.99; 95% confidence interval, 1.520–32.12; P = .012) was an independent risk factor for reoperation. The independent risk factors for moderate-to-severe recurrent regurgitation were residual regurgitation ≥ mild (hazard ratio, 9.60; 95% confidence interval, 3.042–30.31; P < .001) and the loop-in-loop technique (hazard ratio, 3.40; 95% confidence interval, 1.058–10.90; P = .040). The median mean pressure gradient was sustained at almost 3.5 mmHg for > 7 years.

Conclusions

The loop technique with ring annuloplasty provided excellent results with good hemodynamics beyond the mid-term. Residual regurgitation ≥ mild and the loop-in-loop technique may not be preferable for durable outcomes.
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Literature
1.
go back to reference Lawrie GM, Earle EA, Earle NR. Feasibility and intermediate term outcome of repair of prolapsing anterior mitral leaflets with artificial chordal replacement in 152 patients. Ann Thorac Surg. 2006;81:849–56.CrossRef Lawrie GM, Earle EA, Earle NR. Feasibility and intermediate term outcome of repair of prolapsing anterior mitral leaflets with artificial chordal replacement in 152 patients. Ann Thorac Surg. 2006;81:849–56.CrossRef
2.
go back to reference David TE, Armstrong S, Ivanov J. Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience. J Thorac Cardiovasc Surg. 2013;145:1563–9.CrossRef David TE, Armstrong S, Ivanov J. Chordal replacement with polytetrafluoroethylene sutures for mitral valve repair: a 25-year experience. J Thorac Cardiovasc Surg. 2013;145:1563–9.CrossRef
3.
go back to reference Hata H, Fujita T, Shimahara Y, Sato S, Ishibashi-Ueda H, Kobayashi J. A 25-year study of chordal replacement with expanded polytetrafluoroethylene in mitral valve repair. Interact Cardiovasc Thorac Surg. 2015;20:463–8.CrossRef Hata H, Fujita T, Shimahara Y, Sato S, Ishibashi-Ueda H, Kobayashi J. A 25-year study of chordal replacement with expanded polytetrafluoroethylene in mitral valve repair. Interact Cardiovasc Thorac Surg. 2015;20:463–8.CrossRef
4.
go back to reference Falk V, Seeburger J, Czesla M, Borger MA, Willige J, Kuntze T, et al. How does the use of polytetrafluoroethylene neochordae for posterior mitral valve prolapse (loop technique) compare with leaflet resection? A prospective randomized trial. J Thorac Cardiovasc Surg. 2008;136:1200–6.CrossRef Falk V, Seeburger J, Czesla M, Borger MA, Willige J, Kuntze T, et al. How does the use of polytetrafluoroethylene neochordae for posterior mitral valve prolapse (loop technique) compare with leaflet resection? A prospective randomized trial. J Thorac Cardiovasc Surg. 2008;136:1200–6.CrossRef
5.
go back to reference Shibata T, Kato Y, Motoki M, Takahashi Y, Morisaki A, Nishimura S, et al. Mitral valve repair with loop technique via median sternotomy in 180 patients. Eur J Cardiothorac Surg. 2015;47:491–6.CrossRef Shibata T, Kato Y, Motoki M, Takahashi Y, Morisaki A, Nishimura S, et al. Mitral valve repair with loop technique via median sternotomy in 180 patients. Eur J Cardiothorac Surg. 2015;47:491–6.CrossRef
6.
go back to reference Borger MA, Kaeding AF, Seeburger J, Melnitchouk S, Hoebartner M, Winkfein M, et al. Minimally invasive mitral valve repair in Barlow’s disease: early and long-term results. J Thorac Cardiovasc Surg. 2014;148:1379–85.CrossRef Borger MA, Kaeding AF, Seeburger J, Melnitchouk S, Hoebartner M, Winkfein M, et al. Minimally invasive mitral valve repair in Barlow’s disease: early and long-term results. J Thorac Cardiovasc Surg. 2014;148:1379–85.CrossRef
7.
go back to reference Murphy DA, Moss E, Binongo J, Miller JS, Macheers SK, Sarin EL, et al. The expanding role of endoscopic robotics in mitral valve surgery: 1,257 consecutive procedures. Ann Thorac Surg. 2015;100:1675–81.CrossRef Murphy DA, Moss E, Binongo J, Miller JS, Macheers SK, Sarin EL, et al. The expanding role of endoscopic robotics in mitral valve surgery: 1,257 consecutive procedures. Ann Thorac Surg. 2015;100:1675–81.CrossRef
8.
go back to reference David TE, David CM, Tsang W, Lafreniere-Roula M, Manlhiot C. Long-term results of mitral valve repair for regurgitation due to leaflet prolapse. J Am Coll Cardiol. 2019;74:1044–53.CrossRef David TE, David CM, Tsang W, Lafreniere-Roula M, Manlhiot C. Long-term results of mitral valve repair for regurgitation due to leaflet prolapse. J Am Coll Cardiol. 2019;74:1044–53.CrossRef
9.
go back to reference Ram E, Schwammenthal E, Cohen H, Kogan A, Peled Y, Sternik L, et al. Outcomes of degenerative mitral valve repair surgery for anterior, posterior, and bileaflet pathology. Ann Thorac Surg. 2020;110:934–42.CrossRef Ram E, Schwammenthal E, Cohen H, Kogan A, Peled Y, Sternik L, et al. Outcomes of degenerative mitral valve repair surgery for anterior, posterior, and bileaflet pathology. Ann Thorac Surg. 2020;110:934–42.CrossRef
10.
go back to reference Motomura N, Miyata H, Tsukihara H, Takamoto S, Japan Cardiovascular Surgery Database Organization. Risk model of thoracic aortic surgery in 4707 cases from a nationwide single-race population through a web-based data entry system: the first report of 30-day and 30-day operative outcome risk models for thoracic aortic surgery. Circulation. 2008;118:153–9.CrossRef Motomura N, Miyata H, Tsukihara H, Takamoto S, Japan Cardiovascular Surgery Database Organization. Risk model of thoracic aortic surgery in 4707 cases from a nationwide single-race population through a web-based data entry system: the first report of 30-day and 30-day operative outcome risk models for thoracic aortic surgery. Circulation. 2008;118:153–9.CrossRef
11.
go back to reference Morisaki A, Takahashi Y, Fujii H, Sakon Y, Murakami T, Shibata T. Loop technique with ink-dot marking test: an alternative strategy to the ink test. J Thorac Cardiovasc Surg Tech. 2020;3:110–21. Morisaki A, Takahashi Y, Fujii H, Sakon Y, Murakami T, Shibata T. Loop technique with ink-dot marking test: an alternative strategy to the ink test. J Thorac Cardiovasc Surg Tech. 2020;3:110–21.
12.
go back to reference Murashita T, Okada Y, Fujiwara H, Kanemitsu H, Fukunaga N, Konishi Y, et al. Mechanism of and risk factors for reoperation after mitral valve repair for degenerative mitral regurgitation. Circ J. 2013;77:2050–5.CrossRef Murashita T, Okada Y, Fujiwara H, Kanemitsu H, Fukunaga N, Konishi Y, et al. Mechanism of and risk factors for reoperation after mitral valve repair for degenerative mitral regurgitation. Circ J. 2013;77:2050–5.CrossRef
13.
go back to reference Imielski B, Malaisrie SC, Pham DT, Kruse J, Andrei AC, Liu M, et al. The impact of intraoperative residual mild regurgitation after repair of degenerative mitral regurgitation. J Thorac Cardiovasc Surg. 2021;161:1215–24.CrossRef Imielski B, Malaisrie SC, Pham DT, Kruse J, Andrei AC, Liu M, et al. The impact of intraoperative residual mild regurgitation after repair of degenerative mitral regurgitation. J Thorac Cardiovasc Surg. 2021;161:1215–24.CrossRef
14.
go back to reference Tatum JM, Bowdish ME, Mack WJ, Quinn AM, Cohen RG, Hackmann AE, et al. Outcomes after mitral valve repair: a single-center 16-year experience. J Thorac Cardiovasc Surg. 2017;154:822-30.e2.CrossRef Tatum JM, Bowdish ME, Mack WJ, Quinn AM, Cohen RG, Hackmann AE, et al. Outcomes after mitral valve repair: a single-center 16-year experience. J Thorac Cardiovasc Surg. 2017;154:822-30.e2.CrossRef
15.
go back to reference Okamoto K, Yozu R, Kudo M. Loop-in-loop technique in mitral valve repair via minithoracotomy. Ann Thorac Surg. 2012;93:1329–30.CrossRef Okamoto K, Yozu R, Kudo M. Loop-in-loop technique in mitral valve repair via minithoracotomy. Ann Thorac Surg. 2012;93:1329–30.CrossRef
16.
go back to reference Alfieri O, Lapenna E. Systolic anterior motion after mitral valve repair: where do we stand in 2015? Eur J Cardiothorac Surg. 2015;48:344–6.CrossRef Alfieri O, Lapenna E. Systolic anterior motion after mitral valve repair: where do we stand in 2015? Eur J Cardiothorac Surg. 2015;48:344–6.CrossRef
17.
go back to reference Varghese R, Itagaki S, Anyanwu AC, Trigo P, Fischer G, Adams DH. Predicting systolic anterior motion after mitral valve reconstruction: using intraoperative transoesophageal echocardiography to identify those at greatest risk. Eur J Cardiothorac Surg. 2014;45:132–7.CrossRef Varghese R, Itagaki S, Anyanwu AC, Trigo P, Fischer G, Adams DH. Predicting systolic anterior motion after mitral valve reconstruction: using intraoperative transoesophageal echocardiography to identify those at greatest risk. Eur J Cardiothorac Surg. 2014;45:132–7.CrossRef
18.
go back to reference Roshanali F, Naderan M, Shoar S, Vedadian A, Sandoughdaran S, Shoar N, et al. Length of second-order chordae as a predictor of systolic anterior motion of the mitral valve. Interact Cardiovasc Thorac Surg. 2016;23:280–5.CrossRef Roshanali F, Naderan M, Shoar S, Vedadian A, Sandoughdaran S, Shoar N, et al. Length of second-order chordae as a predictor of systolic anterior motion of the mitral valve. Interact Cardiovasc Thorac Surg. 2016;23:280–5.CrossRef
19.
go back to reference Lawrie GM, Zoghbi W, Little S, Shah D, Ben-Zekry Z, Earle N, et al. One hundred percent reparability of degenerative mitral regurgitation: intermediate-term results of a dynamic engineered approach. Ann Thorac Surg. 2016;101:576–83.CrossRef Lawrie GM, Zoghbi W, Little S, Shah D, Ben-Zekry Z, Earle N, et al. One hundred percent reparability of degenerative mitral regurgitation: intermediate-term results of a dynamic engineered approach. Ann Thorac Surg. 2016;101:576–83.CrossRef
20.
go back to reference Salvador L, Mirone S, Bianchini R, Regesta T, Patelli F, Minniti G, et al. A 20-year experience with mitral valve repair with artificial chordae in 608 patients. J Thorac Cardiovasc Surg. 2008;135:1280–7.CrossRef Salvador L, Mirone S, Bianchini R, Regesta T, Patelli F, Minniti G, et al. A 20-year experience with mitral valve repair with artificial chordae in 608 patients. J Thorac Cardiovasc Surg. 2008;135:1280–7.CrossRef
21.
go back to reference Jahren SE, Hurni S, Heinisch PP, Winkler B, Obrist D, Carrel T, et al. Transvalvular pressure gradients for different methods of mitral valve repair: only neochordoplasty achieves native valve gradients. Interact Cardiovasc Thorac Surg. 2018;26:248–55.CrossRef Jahren SE, Hurni S, Heinisch PP, Winkler B, Obrist D, Carrel T, et al. Transvalvular pressure gradients for different methods of mitral valve repair: only neochordoplasty achieves native valve gradients. Interact Cardiovasc Thorac Surg. 2018;26:248–55.CrossRef
22.
go back to reference Kitahara H, Murata M, Okamoto K, Kudo M, Yoshitake A, Tsuruta H, et al. Preservation of mobility of the posterior mitral leaflet after mitral valve repair with neochordae using loop technique. Circ J. 2016;80:663–7.CrossRef Kitahara H, Murata M, Okamoto K, Kudo M, Yoshitake A, Tsuruta H, et al. Preservation of mobility of the posterior mitral leaflet after mitral valve repair with neochordae using loop technique. Circ J. 2016;80:663–7.CrossRef
23.
go back to reference Pfannmueller B, Misfeld M, Verevkin A, Garbade J, Holzhey DM, Davierwala P, et al. Loop neochord versus leaflet resection techniques for minimally invasive mitral valve repair: long-term results. Eur J Cardiothorac Surg. 2021;59:180–6.CrossRef Pfannmueller B, Misfeld M, Verevkin A, Garbade J, Holzhey DM, Davierwala P, et al. Loop neochord versus leaflet resection techniques for minimally invasive mitral valve repair: long-term results. Eur J Cardiothorac Surg. 2021;59:180–6.CrossRef
Metadata
Title
Outcomes of loop technique with ring annuloplasty: a > 10-year experience
Authors
Akimasa Morisaki
Yosuke Takahashi
Hiromichi Fujii
Yoshito Sakon
Takashi Murakami
Toshihiko Shibata
Publication date
29-03-2022
Publisher
Springer Nature Singapore
Published in
General Thoracic and Cardiovascular Surgery / Issue 9/2022
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-022-01804-8

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