Skip to main content
Top
Published in: General Thoracic and Cardiovascular Surgery 2/2019

01-02-2019 | Current Topics Review Article

Perioperative intervention by oral medicine team in cardiovascular surgery patients

Authors: Masaya Akashi, Nagisa Nanba, Junya Kusumoto, Takahide Komori

Published in: General Thoracic and Cardiovascular Surgery | Issue 2/2019

Login to get access

Abstract

In brief, perioperative oral intervention consists of elimination of odontogenic foci and maintenance of oral hygiene in patients undergoing surgery. The importance of oral intervention before, during, and after medical treatments is well-known, especially in cancer patients, because odontogenic foci such as untreated deep dental caries or periodontitis can cause systemic infection in patients with myelosuppression resulting from chemotherapy. Although perioperative oral intervention is currently recommended for patients with cardiovascular disease, its efficacy in this population has not been established. This article consists of three sections: first, we review the current knowledge about the association between dental disease and cardiovascular disease to show the importance of oral hygiene maintenance and the risks of invasive dental procedures in patients with cardiovascular disease; second, we introduce pertinent, but limited evidence concerning the effect of oral care in preventing postoperative pneumonia; and finally, we present the optimal strategy for perioperative oral intervention in cardiovascular surgery patients.
Literature
1.
go back to reference Elad S, Raber-Durlacher JE, Brennan MT, Saunders DP, Mank AP, Zadik Y, et al. Basic oral care for hematology-oncology patients and hematopoietic stem cell transplantation recipients: a position paper from the joint task force of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT). Support Care Cancer. 2015;23(1):223–36.CrossRefPubMed Elad S, Raber-Durlacher JE, Brennan MT, Saunders DP, Mank AP, Zadik Y, et al. Basic oral care for hematology-oncology patients and hematopoietic stem cell transplantation recipients: a position paper from the joint task force of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT). Support Care Cancer. 2015;23(1):223–36.CrossRefPubMed
2.
go back to reference Kishimoto M, Akashi M, Tsuji K, Kusumoto J, Furudoi S, Shibuya Y, et al. Intensity and duration of neutropenia relates to the development of oral mucositis but not odontogenic infection during chemotherapy for hematological malignancy. PLoS One. 2017;12(7):e0182021.CrossRefPubMedPubMedCentral Kishimoto M, Akashi M, Tsuji K, Kusumoto J, Furudoi S, Shibuya Y, et al. Intensity and duration of neutropenia relates to the development of oral mucositis but not odontogenic infection during chemotherapy for hematological malignancy. PLoS One. 2017;12(7):e0182021.CrossRefPubMedPubMedCentral
3.
go back to reference Akashi M, Shibuya Y, Kusumoto J, Furudoi S, Inui Y, Yakushijin K, et al. Myelosuppression grading of chemotherapies for hematologic malignancies to facilitate communication between medical and dental staff: lessons from two cases experienced odontogenic septicemia. BMC Oral Health. 2013;13:41.CrossRefPubMedPubMedCentral Akashi M, Shibuya Y, Kusumoto J, Furudoi S, Inui Y, Yakushijin K, et al. Myelosuppression grading of chemotherapies for hematologic malignancies to facilitate communication between medical and dental staff: lessons from two cases experienced odontogenic septicemia. BMC Oral Health. 2013;13:41.CrossRefPubMedPubMedCentral
4.
go back to reference McGuire DB, Fulton JS, Park J, Brown CG, Correa ME, Eilers J, et al. Systematic review of basic oral care for the management of oral mucositis in cancer patients. Support Care Cancer. 2013;21(11):3165–77.CrossRefPubMed McGuire DB, Fulton JS, Park J, Brown CG, Correa ME, Eilers J, et al. Systematic review of basic oral care for the management of oral mucositis in cancer patients. Support Care Cancer. 2013;21(11):3165–77.CrossRefPubMed
5.
go back to reference Soutome S, Yanamoto S, Funahara M, Hasegawa T, Komori T, Yamada SI, et al. Effect of perioperative oral care on prevention of postoperative pneumonia associated with esophageal cancer surgery: A multicenter case-control study with propensity score matching analysis. Medicine (Baltimore). 2017;96(33):e7436.CrossRef Soutome S, Yanamoto S, Funahara M, Hasegawa T, Komori T, Yamada SI, et al. Effect of perioperative oral care on prevention of postoperative pneumonia associated with esophageal cancer surgery: A multicenter case-control study with propensity score matching analysis. Medicine (Baltimore). 2017;96(33):e7436.CrossRef
6.
go back to reference Sjögren P, Nilsson E, Forsell M, Johansson O, Hoogstraate J. A systematic review of the preventive effect of oral hygiene on pneumonia and respiratory tract infection in elderly people in hospitals and nursing homes: effect estimates and methodological quality of randomized controlled trials. J Am Geriatr Soc. 2008;56(11):2124–30.CrossRef Sjögren P, Nilsson E, Forsell M, Johansson O, Hoogstraate J. A systematic review of the preventive effect of oral hygiene on pneumonia and respiratory tract infection in elderly people in hospitals and nursing homes: effect estimates and methodological quality of randomized controlled trials. J Am Geriatr Soc. 2008;56(11):2124–30.CrossRef
7.
go back to reference Kaneoka A, Pisegna JM, Miloro KV, Lo M, Saito H, Riquelme LF, et al. Prevention of healthcare-associated pneumonia with oral care in individuals without mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials. Infect Control Hosp Epidemiol. 2015;36(8):899–906.CrossRefPubMed Kaneoka A, Pisegna JM, Miloro KV, Lo M, Saito H, Riquelme LF, et al. Prevention of healthcare-associated pneumonia with oral care in individuals without mechanical ventilation: a systematic review and meta-analysis of randomized controlled trials. Infect Control Hosp Epidemiol. 2015;36(8):899–906.CrossRefPubMed
8.
go back to reference Arpin S. Oral hygiene in elderly people in hospitals and nursing homes. Evid Based Dent. 2009;10(2):46.CrossRefPubMed Arpin S. Oral hygiene in elderly people in hospitals and nursing homes. Evid Based Dent. 2009;10(2):46.CrossRefPubMed
9.
go back to reference Shi Z, Xie H, Wang P, Zhang Q, Wu Y, Chen E, et al. Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev. 2013;(8):CD008367. Shi Z, Xie H, Wang P, Zhang Q, Wu Y, Chen E, et al. Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev. 2013;(8):CD008367.
10.
go back to reference Hua F, Xie H, Worthington HV, Furness S, Zhang Q, Li C. Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev. 2016;10:CD008367.PubMed Hua F, Xie H, Worthington HV, Furness S, Zhang Q, Li C. Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev. 2016;10:CD008367.PubMed
11.
go back to reference Jenkins GW, Holmes A, Colman-Nally J, Mustafa S. What is the role of the oral and maxillofacial department in the preoperative management of patients awaiting cardiac operations? Br J Oral Maxillofac Surg. 2015;53(5):442–5.CrossRefPubMed Jenkins GW, Holmes A, Colman-Nally J, Mustafa S. What is the role of the oral and maxillofacial department in the preoperative management of patients awaiting cardiac operations? Br J Oral Maxillofac Surg. 2015;53(5):442–5.CrossRefPubMed
12.
go back to reference Demmer RT, Desvarieux M. Periodontal infections and cardiovascular disease: the heart of the matter. J Am Dent Assoc. 2006;137:14S–20S (quiz 38S) CrossRef Demmer RT, Desvarieux M. Periodontal infections and cardiovascular disease: the heart of the matter. J Am Dent Assoc. 2006;137:14S–20S (quiz 38S) CrossRef
13.
go back to reference Tonetti MS, Van Dyke TE. working group 1 of the joint EFP/AAP workshop. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013;84(4 Suppl):24–9. Tonetti MS, Van Dyke TE. working group 1 of the joint EFP/AAP workshop. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013;84(4 Suppl):24–9.
14.
go back to reference Beukers NG, van der Heijden GJ, van Wijk AJ, Loos BG. Periodontitis is an independent risk indicator for atherosclerotic cardiovascular diseases among 60,174 participants in a large dental school in the Netherlands. J Epidemiol Community Health. 2017;71(1):37–42.CrossRefPubMed Beukers NG, van der Heijden GJ, van Wijk AJ, Loos BG. Periodontitis is an independent risk indicator for atherosclerotic cardiovascular diseases among 60,174 participants in a large dental school in the Netherlands. J Epidemiol Community Health. 2017;71(1):37–42.CrossRefPubMed
15.
go back to reference Holmlund A, Lampa E, Lind L. Poor response to periodontal treatment may predict future cardiovascular disease. J Dent Res. 2017;96(7):768–73.CrossRefPubMed Holmlund A, Lampa E, Lind L. Poor response to periodontal treatment may predict future cardiovascular disease. J Dent Res. 2017;96(7):768–73.CrossRefPubMed
16.
go back to reference Liljestrand JM, Havulinna AS, Paju S, Männistö S, Salomaa V, Pussinen PJ. Missing teeth predict incident cardiovascular events, diabetes, and death. J Dent Res. 2015;94(8):1055–62.CrossRefPubMed Liljestrand JM, Havulinna AS, Paju S, Männistö S, Salomaa V, Pussinen PJ. Missing teeth predict incident cardiovascular events, diabetes, and death. J Dent Res. 2015;94(8):1055–62.CrossRefPubMed
17.
go back to reference Dietrich T, Walter C, Oluwagbemigun K, Bergmann M, Pischon T, Pischon N, et al. Smoking, smoking cessation, and risk of tooth loss: the EPIC-potsdam study. J Dent Res. 2015;94(10):1369–75.CrossRefPubMed Dietrich T, Walter C, Oluwagbemigun K, Bergmann M, Pischon T, Pischon N, et al. Smoking, smoking cessation, and risk of tooth loss: the EPIC-potsdam study. J Dent Res. 2015;94(10):1369–75.CrossRefPubMed
18.
go back to reference Hanioka T, Ojima M, Tanaka K, Matsuo K, Sato F, Tanaka H. Causal assessment of smoking and tooth loss: a systematic review of observational studies. BMC Public Health. 2011;11:221.CrossRefPubMedPubMedCentral Hanioka T, Ojima M, Tanaka K, Matsuo K, Sato F, Tanaka H. Causal assessment of smoking and tooth loss: a systematic review of observational studies. BMC Public Health. 2011;11:221.CrossRefPubMedPubMedCentral
19.
go back to reference Brook I. The impact of smoking on oral and nasopharyngeal bacterial flora. J Dent Res. 2011;90(6):704–10.CrossRefPubMed Brook I. The impact of smoking on oral and nasopharyngeal bacterial flora. J Dent Res. 2011;90(6):704–10.CrossRefPubMed
20.
go back to reference Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, et al. High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm. Int Heart J. 2014;55(3):268–70.CrossRefPubMed Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, et al. High incidence of periodontitis in Japanese patients with abdominal aortic aneurysm. Int Heart J. 2014;55(3):268–70.CrossRefPubMed
21.
go back to reference Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, et al. Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia. Heart Vessels. 2015;30(4):498–502.CrossRefPubMed Suzuki J, Aoyama N, Aoki M, Tada Y, Wakayama K, Akazawa H, et al. Incidence of periodontitis in Japanese patients with cardiovascular diseases: a comparison between abdominal aortic aneurysm and arrhythmia. Heart Vessels. 2015;30(4):498–502.CrossRefPubMed
22.
go back to reference Ding F, Lyu Y, Han X, Zhang H, Liu D, Hei W, et al. Detection of periodontal pathogens in the patients with aortic aneurysm. Chin Med J. 2014;127(23):4114–8.PubMed Ding F, Lyu Y, Han X, Zhang H, Liu D, Hei W, et al. Detection of periodontal pathogens in the patients with aortic aneurysm. Chin Med J. 2014;127(23):4114–8.PubMed
23.
go back to reference Nakano K, Wada K, Nomura R, Nemoto H, Inaba H, Kojima A, et al. Characterization of aortic aneurysms in cardiovascular disease patients harboring porphyromonas gingivalis. Oral Dis. 2011;17(4):370–8.CrossRefPubMed Nakano K, Wada K, Nomura R, Nemoto H, Inaba H, Kojima A, et al. Characterization of aortic aneurysms in cardiovascular disease patients harboring porphyromonas gingivalis. Oral Dis. 2011;17(4):370–8.CrossRefPubMed
24.
go back to reference Gibson FC 3rd, Yumoto H, Takahashi Y, Chou HH, Genco CA. Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis. J Dent Res. 2006;85(2):106–21.CrossRefPubMed Gibson FC 3rd, Yumoto H, Takahashi Y, Chou HH, Genco CA. Innate immune signaling and Porphyromonas gingivalis-accelerated atherosclerosis. J Dent Res. 2006;85(2):106–21.CrossRefPubMed
25.
go back to reference Hokamura K, Umemura K. Roles of oral bacteria in cardiovascular diseases—from molecular mechanisms to clinical cases: Porphyromonas gingivalis is the important role of intimal hyperplasia in the aorta. J Pharmacol Sci. 2010;113(2):110–4.CrossRefPubMed Hokamura K, Umemura K. Roles of oral bacteria in cardiovascular diseases—from molecular mechanisms to clinical cases: Porphyromonas gingivalis is the important role of intimal hyperplasia in the aorta. J Pharmacol Sci. 2010;113(2):110–4.CrossRefPubMed
26.
go back to reference McCormick MM, Rahimi F, Bobryshev YV, Gaus K, Zreiqat H, Cai H, et al. S100A8 and S100A9 in human arterial wall. Implications for atherogenesis. J Biol Chem. 2005;280(50):41521–9.CrossRefPubMed McCormick MM, Rahimi F, Bobryshev YV, Gaus K, Zreiqat H, Cai H, et al. S100A8 and S100A9 in human arterial wall. Implications for atherogenesis. J Biol Chem. 2005;280(50):41521–9.CrossRefPubMed
27.
go back to reference Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH. Incidence of infective endocarditis in England, 2000-13: a secular trend, interrupted time-series analysis. Lancet. 2015;385(9974):1219–28.CrossRefPubMed Dayer MJ, Jones S, Prendergast B, Baddour LM, Lockhart PB, Thornhill MH. Incidence of infective endocarditis in England, 2000-13: a secular trend, interrupted time-series analysis. Lancet. 2015;385(9974):1219–28.CrossRefPubMed
28.
go back to reference Lockhart PB, Brennan MT, Cook WH, Sasser H, Lovell RD, Skipper ER, et al. Concomitant surgical treatment of dental and valvular heart diseases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(1):71–6.CrossRefPubMed Lockhart PB, Brennan MT, Cook WH, Sasser H, Lovell RD, Skipper ER, et al. Concomitant surgical treatment of dental and valvular heart diseases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107(1):71–6.CrossRefPubMed
29.
go back to reference Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007;116(15):1736–54.CrossRefPubMed Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007;116(15):1736–54.CrossRefPubMed
30.
go back to reference Richey R, Wray D, Stokes T, Guideline Development Group. Prophylaxis against infective endocarditis: summary of NICE guidance. BMJ. 2008;336(7647):770–1.CrossRefPubMedPubMedCentral Richey R, Wray D, Stokes T, Guideline Development Group. Prophylaxis against infective endocarditis: summary of NICE guidance. BMJ. 2008;336(7647):770–1.CrossRefPubMedPubMedCentral
31.
go back to reference Thornhill MH, Dayer M, Lockhart PB, McGurk M, Shanson D, Prendergast B, et al. A change in the NICE guidelines on antibiotic prophylaxis. Br Dent J. 2016;221(3):112–4.CrossRefPubMed Thornhill MH, Dayer M, Lockhart PB, McGurk M, Shanson D, Prendergast B, et al. A change in the NICE guidelines on antibiotic prophylaxis. Br Dent J. 2016;221(3):112–4.CrossRefPubMed
32.
go back to reference Smith MM, Barbara DW, Mauermann WJ, Viozzi CF, Dearani JA, Grim KJ. Morbidity and mortality associated with dental extraction before cardiac operation. Ann Thorac Surg. 2014;97(3):838–44.CrossRefPubMed Smith MM, Barbara DW, Mauermann WJ, Viozzi CF, Dearani JA, Grim KJ. Morbidity and mortality associated with dental extraction before cardiac operation. Ann Thorac Surg. 2014;97(3):838–44.CrossRefPubMed
33.
go back to reference Nakamura Y, Tagusari O, Seike Y, Ito Y, Saito K, Miyamoto R, et al. Prevalence of periodontitis and optimal timing of dental treatment in patients undergoing heart valve surgery. Interact Cardiovasc Thorac Surg. 2011;12(5):696–700.CrossRefPubMed Nakamura Y, Tagusari O, Seike Y, Ito Y, Saito K, Miyamoto R, et al. Prevalence of periodontitis and optimal timing of dental treatment in patients undergoing heart valve surgery. Interact Cardiovasc Thorac Surg. 2011;12(5):696–700.CrossRefPubMed
34.
go back to reference Umino M, Ohwatari T, Shimoyama K, Nagao M. Unexpected atrial fibrillation during tooth extraction in a sedated elderly patient. Anesth Prog. 1994;41(3):77–80.PubMedPubMedCentral Umino M, Ohwatari T, Shimoyama K, Nagao M. Unexpected atrial fibrillation during tooth extraction in a sedated elderly patient. Anesth Prog. 1994;41(3):77–80.PubMedPubMedCentral
35.
go back to reference Peters KA, Triolo PT, Darden DL. Disseminated intravascular coagulopathy: manifestations after a routine dental extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99(4):419–23.CrossRefPubMed Peters KA, Triolo PT, Darden DL. Disseminated intravascular coagulopathy: manifestations after a routine dental extraction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99(4):419–23.CrossRefPubMed
36.
go back to reference Imai T, Michizawa M, Shimizu H, Yura Y, Doi Y. Spontaneous intraoral hemorrhage as manifestation of thoracoabdominal aortic aneurysm-associated disseminated intravascular coagulation: case report and review. J Oral Maxillofac Surg. 2010;68(1):195–200.CrossRefPubMed Imai T, Michizawa M, Shimizu H, Yura Y, Doi Y. Spontaneous intraoral hemorrhage as manifestation of thoracoabdominal aortic aneurysm-associated disseminated intravascular coagulation: case report and review. J Oral Maxillofac Surg. 2010;68(1):195–200.CrossRefPubMed
37.
go back to reference Seto M, Matsuda M, Narihira K, Kikuta T. Oral surgery under local anesthesia with dexmedetomidine sedation in a morbidly obese patient with aortic dissection. J Korean Assoc Oral Maxillofac Surg. 2016;42(2):162–5.CrossRefPubMedPubMedCentral Seto M, Matsuda M, Narihira K, Kikuta T. Oral surgery under local anesthesia with dexmedetomidine sedation in a morbidly obese patient with aortic dissection. J Korean Assoc Oral Maxillofac Surg. 2016;42(2):162–5.CrossRefPubMedPubMedCentral
38.
go back to reference Garcia R. A review of the possible role of oral and dental colonization on the occurrence of health care-associated pneumonia: underappreciated risk and a call for interventions. Am J Infect Control. 2005;33(9):527–41.CrossRefPubMed Garcia R. A review of the possible role of oral and dental colonization on the occurrence of health care-associated pneumonia: underappreciated risk and a call for interventions. Am J Infect Control. 2005;33(9):527–41.CrossRefPubMed
39.
go back to reference Starks B, Harbert C. Aspiration prevention protocol: decreasing postoperative pneumonia in heart surgery patients. Crit Care Nurse. 2011;31(5):38–45.CrossRefPubMed Starks B, Harbert C. Aspiration prevention protocol: decreasing postoperative pneumonia in heart surgery patients. Crit Care Nurse. 2011;31(5):38–45.CrossRefPubMed
40.
go back to reference Bergan EH, Tura BR, Lamas CC. Impact of improvement in preoperative oral health on nosocomial pneumonia in a group of cardiac surgery patients: a single arm prospective intervention study. Intensive Care Med. 2014;40(1):23–31.CrossRefPubMed Bergan EH, Tura BR, Lamas CC. Impact of improvement in preoperative oral health on nosocomial pneumonia in a group of cardiac surgery patients: a single arm prospective intervention study. Intensive Care Med. 2014;40(1):23–31.CrossRefPubMed
41.
go back to reference Allou N, Bronchard R, Guglielminotti J, Dilly MP, Provenchere S, Lucet JC, et al. Risk factors for postoperative pneumonia after cardiac surgery and development of a preoperative risk score*. Crit Care Med. 2014;42(5):1150–6.CrossRefPubMed Allou N, Bronchard R, Guglielminotti J, Dilly MP, Provenchere S, Lucet JC, et al. Risk factors for postoperative pneumonia after cardiac surgery and development of a preoperative risk score*. Crit Care Med. 2014;42(5):1150–6.CrossRefPubMed
42.
go back to reference Strobel RJ, Liang Q, Zhang M, Wu X, Rogers MA, Theurer PF, et al. A preoperative risk model for postoperative pneumonia after coronary artery bypass grafting. Ann Thorac Surg. 2016;102(4):1213–9.CrossRefPubMedPubMedCentral Strobel RJ, Liang Q, Zhang M, Wu X, Rogers MA, Theurer PF, et al. A preoperative risk model for postoperative pneumonia after coronary artery bypass grafting. Ann Thorac Surg. 2016;102(4):1213–9.CrossRefPubMedPubMedCentral
43.
go back to reference Santos M, Braga JU, Gomes RV, Werneck GL. Predictive factors for pneumonia onset after cardiac surgery in Rio de Janeiro, Brazil. Infect Control Hosp Epidemiol. 2007;28(4):382–8.CrossRefPubMed Santos M, Braga JU, Gomes RV, Werneck GL. Predictive factors for pneumonia onset after cardiac surgery in Rio de Janeiro, Brazil. Infect Control Hosp Epidemiol. 2007;28(4):382–8.CrossRefPubMed
44.
go back to reference Miller PD Jr. A classification of marginal tissue recession. Int J Periodontics Restorative Dent. 1985;5(2):8–13.PubMed Miller PD Jr. A classification of marginal tissue recession. Int J Periodontics Restorative Dent. 1985;5(2):8–13.PubMed
45.
46.
go back to reference Klompas M, Speck K, Howell MD, Greene LR, Berenholtz SM. Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis. JAMA Intern Med. 2014;174(5):751–61.CrossRefPubMed Klompas M, Speck K, Howell MD, Greene LR, Berenholtz SM. Reappraisal of routine oral care with chlorhexidine gluconate for patients receiving mechanical ventilation: systematic review and meta-analysis. JAMA Intern Med. 2014;174(5):751–61.CrossRefPubMed
Metadata
Title
Perioperative intervention by oral medicine team in cardiovascular surgery patients
Authors
Masaya Akashi
Nagisa Nanba
Junya Kusumoto
Takahide Komori
Publication date
01-02-2019
Publisher
Springer Singapore
Published in
General Thoracic and Cardiovascular Surgery / Issue 2/2019
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-018-1020-0

Other articles of this Issue 2/2019

General Thoracic and Cardiovascular Surgery 2/2019 Go to the issue